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Beyond potency and selectivity, ADME/PK and the toxicological profile of the compound play a significant role in its evaluation as a candidate for development. The possibility that the presence of this fragile site is linked to mental retardation is discussed. The neural mechanisms underlying this memory involve changes at the reciprocal dendrodendritic synapses between glutamatergic mitral cells and gamma-aminobutyric acid (GABA)-ergic granule cells in the accessory olfactory bulb (AOB). Neuroimaging of six neurosyphilis cases mimicking viral encephalitis. It is now clear that chronic lymphocytic leukemia is a relatively proliferative disorder that requires the help of its microenvironment to be maintained and to progress. Isotretinoin is known to be the treatment of choice for severe acne. Some formae speciales are not primarily vascular pathogens but cause foot- and rootrot or bulbrot. Dentists are in a unique position to advise smokers to quit by providing effective counseling on the various aspects of tobacco-induced diseases.
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