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Acneril (Adapalene)

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Acneril is used to treat acne. Acneril is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin. Acneril has the unique ability to inhibit keratinocyte differentiation and decrease keratin deposition.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Sildigra, Moduretic, Silagra, Dostinex, Atarax, Pepmark, Hycoril, Enalagamma, Ralosto, Tetradar, Zeriphylline, Luzarn, Supermet,

Also known as: Adapalene


Acneril is a third-generation topical retinoid primarily used in the treatment of acne. Acneril is a gel used for the treatment of acne (blackheads, whiteheads and pimples) of the face, chest or back. Acneril gel is a clear gel that powers deep inside your pores to control the buildup that leads to acne. It helps prevent the formation of new acne lesions, and can also help get rid of lesions already present. Acneril works under the skin surface to unclog pores and clear up pimples. Acneril is also known as Adapalene, Adapen, Adaferin. Generic name of Acneril is Adapalene.


Follow the directions for using this medicine provided by your doctor. Use Acneril exactly as directed. Acneril is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Acneril. Acneril should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Acneril. Continue using Acneril until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Acneril promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Acneril and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Acneril dosage information

Side effects

The most common side effects associated with Acneril are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Since many giant aneurysms are found inoperable during exploration with application of DHCA, it would change the fate of the patients, and the clinical value of DHCA in such an instance becomes contradictive and disputable. This study was undertaken to evaluate the haemodynamic changes of tracheal extubation or removal of a laryngeal mask airway (LMA) in normotensive and hypertensive patients. Our study suggests that mass spectrometry combined to a strong bioinformatics analysis is a valuable tool for the identification of quali/quantitative differences in the serum proteome of otherwise indistinguishable FAP phenotypes. In this study, we assessed the relationship between asymptomatic bacteriuria and pre-eclampsia. In-depth analysis of interreader agreement and accuracy in categorical assessment of brown adipose tissue in (18)FDG-PET/CT. Effects of valsartan, mycophenolate mofetil and their combined application on TRAIL and nuclear factor-kappaB expression in the kidneys of diabetic rats.

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PicXAA greedily builds up the alignment from sequence regions with high local similarity, thereby yielding an accurate global alignment that effectively captures the local similarities across sequences. Can it be retired from the analysis of case-control association studies?. Association of Community Health Nursing Educators: disaster preparedness white paper for community/public health nursing educators. Simultaneous modulations of stimulus luminance and color at different frequencies were utilized to induce intermodulation frequencies. Mirtazapine effects on alertness and sleep in patients as recorded by interactive telecommunication during treatment with different dosing regimens. The Duo-STIM, a new, programmable and portable neuromuscular stimulation system for drop foot correction and blood flow assist applications is presented. Numbers of programmed death-1 (PD-1) positive T cells have prognostic significance in some types of nodal B-cell lymphomas, but data on PD-1 expression in cutaneous B-cell lymphoma (CBCL) are few. The simulation showed that tight coadaptation of parent and offspring traits only occurred in iteroparous outcomes whereas semelparous outcomes were characterized by weak coadaptation. The incidence of vasospasm detected by TCD was significantly higher in Group II. Low-Level Laser Therapy in Russia: History, Science and Practice.

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Six different monoclonal IgG mouse antibodies to heparin lyase I from Flavobacterium heparinum were prepared. Differential enzymatic reductions governing the differential hypoxia-selective cytotoxicities of phenazine 5,10-dioxides. Lack of CSB expression does not impair Pol I transcription, showing that CSB is not essential for ribosomal transcription. Necrotizing glomerulonephritis in presence of 2 ANCA specificities. Changes in the concentration of a single macromer were shown to provide effective variation of degradation, but with corresponding significant changes in tensile properties. Anonymity can foster discussion on personal characteristics and biases. The presence of oral candidiasis and weight loss were highly predictive of low CD4 counts and these can be considered as markers of HIV disease progression. Our data stress the importance of YSM on BMDTrab and BMDCorti, of age at menarche on BMDCorti and of gynecological age on BMDTrab. The management of nuchal cord with a single loop, suspected before delivery, seems clear: it should not influence the clinical management. Since the radiation risk to staff members is low, a classification of the personnel in the operating room and in the pathology laboratories as occupational radiation exposed workers is not necessary.

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In two cases of chronic schizophrenia complicated by diabetes mellitus, the concomitant use of the neuroleptica and oral antidiabetics was attended by the appearance of symptoms simulative of syndrome malin, i.e. This Review provides an introduction to the biological challenges that siRNA delivery materials aim to overcome, as well as a discussion of the way that the most effective and clinically advanced classes of siRNA delivery systems, including lipid nanoparticles and siRNA conjugates, are designed to surmount these challenges. For dynamic imaging, gadoxetic acid was administrated and data were collected for a period of 5 to 40 minutes after injection. Mesoheme monosulfuric anhydride reacts at three distinct sites in soybean apoleghemoglobin a, at lysine-6, lysine-19 and lysine-57, the last one being the major site of reaction. When the VFA was pure acetic or propionic acid, the proposed PAO (or GAO) model reverted back to the reported acetate or propionate PAO (or GAO) model. A principal goal of microarray studies is to identify the genes showing differential expression under distinct conditions. Discussions with health professionals about the possible impact of treatment adverse effects on employment, good communication with employers, and workplace flexibility may facilitate return to work for this population. The pollution of butyltins and phenyltins in aquatic food and dimethyltin in port wine were prevalent. Four additional canisters were used as controls and discharged simultaneously through the standard actuator. hikaru genki, a CNS-specific gene identified by abnormal locomotion in Drosophila, encodes a novel type of protein.

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B-Vitamin Serum Concentrations Predicting Long-Term Overall and Stroke-Free Survival after Carotid Endarterectomy. Human Navigation: Occipital Place Area Detects Potential Paths in a Scene. The areas of space to which these units responded (their receptive fields) were largely independent of the nature and intensity of the sound stimulus. The purpose of the study was to evaluate the effect of AV junction ablation and pacemaker implantation on quality of life and specific symptoms in patients with paroxysmal atrial fibrillation (AF) not controlled by drugs. It is shown that the temporal delay between the plasma breakdown and the appearance of the instabilities is on the order of 10-100 ms.

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Breeding experiments to combine the X-linked sparse-fur (spf) mutation with the autosomal recessive BALB/cByJ strain: testing the biochemical phenotype of double-mutant mice as a model for ammonia: fatty acyl CoA synergism. This article addresses some of the background to this therapeutic problem and discusses some of the issues ahead. Levels of serum-soluble interleukin-2 receptors (serum sIL-2R) are thought to indicate the activation of immunocompetent cells, mainly lymphocytes. Evaluation of Screening US-detected Breast Masses by Combined Use of Elastography and Color Doppler US with B-Mode US in Women with Dense Breasts: A Multicenter Prospective Study. There is no evidence of insecticide resistance associated with gene amplification in this enzyme class. Biomimetic Molecular Signaling using DNA Walkers on Microparticles. Dermal-like tissue applied by the surgeon elicited no adverse reactions, and was fully integrated and well-vascularized by 1-3 weeks. Adrenalectomy-induced granule cell degeneration in the rat hippocampal dentate gyrus: characterization of an in vivo model of controlled neuronal death. Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome. Microcirculatory measurements were obtained at 5 time points ranging from induction of anesthesia to ICU admission.

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Unlike the AIs, SERMs have a distinct function that does not directly relate to hormone receptors when used in higher pharmacological concentration. These optimal cut-offs differed markedly when only sera from either endemic or epidemic cases were used for cut-off determination. Penfluridol, an oral neuroleptic administered weekly was as efficacious as fluphenazine administered twice daily and appeared to be superior to fluphenazine in improving emotional withdrawal and anergia. Intact viroplasmic centers were isolated from Estigmene acres cells infected with Tipula iridescent virus (TIV) by homogenization, followed by differential and discontinuous sucrose gradient centrifugation. Postoperative blood loss and postoperative respiratory complications might be the factors responsible for delayed extubation in ITx patients. Is It Feasible to Treat Odontoid Fractures via Primary Posterior Reduction and Fixation without Fusion?. Carbonic anhydrases and their interplay with acid/base-coupled membrane transporters. Intelligent cost containment measures must include application of disciplined logic to the decision making process of when to use high-tech, high-cost interventions.

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Adult patients admitted for acute treatment and rehabilitation after traumatic spinal cord injury were recruited. An animal model for the study of Chamomilla in stress and depression: pilot study. To close this gap, we applied an integrative proteomic approach that combines cell fractionation, protein chromatography and quantitative mass spectrometry (MS) to analyze the oligomerization state of thousands of proteins in a single experiment. Umbilical cord blood (UCB) is increasingly being used as a donor source of hematopoietic stem cells (HSCs) to treat blood malignancies. All 32 subjects received 200 mg fluconazole every 24 hours beginning on day 11 and continuing through day 20. Overall, the data indicate that IFNIs play a promoting role in C. In the evaluation of the former our limited data suggested that spinal anesthesia is less preferable than other alternatives in MS. In the present study, the regression approach was tested with tasks (memory scanning and mental rotation) that involved a selective effect and with a task (word superiority effect) that involved a global effect, by the dominant theories.

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We study the linear and nonlinear optical properties of hybrid metallic-dielectric plasmonic gap nanoantennas. Consensus statement: Using laryngeal electromyography for the diagnosis and treatment of vocal cord paralysis. This paper describes the technique, indications and results of investigations in 70 patients suffering from cerebrovascular diseases. Modification of Turnip yellow mosaic virus coat protein and its effect on virion assembly. However, fewer interventions were required by the anaesthetist during the use of TCI compared with MCI. Accordingly, Prx hyperoxidation signals that H2O2 defenses are breached, diverting thioredoxin to repair damage. Complete duplex kidney is often complicated by urinary tract abnormalities such as ectopic ureterocele, VUR, and renal dysplasia, and these complications complicate its diagnosis. Policies and procedures reflecting the innovative character of the new peer review process were developed based on legal/regulatory requirements and desired educational focus of the process. The effects of neuromodulation in a novel obese-prone rat model of detrusor underactivity.

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Although remote ischemic conditioning promises significant benefit to patients with a variety of acute and chronic illnesses, development of automated, clinically applicable devices has been slow. Improved foot position sense as a result of repetitions in older adults. The SWI/SNF tumor suppressor complex: Regulation of promoter nucleosomes and beyond. It was shown that a torsion of 1 or 2 times in the distal ureter does not result in ureteral obstruction. Autoimmune mechanisms in the pathogenesis of neurologic paraneoplastic diseases. A prospective study was carried out in women who underwent laparoscopy within the diagnostic process of primary infertility between January 2005 and January 2007. Four kinds of cellulose derivatives, including two regioselectively substituted cellulose esters (6-O-acetyl-2,3-di-O-benzoyl cellulose and 2,3-di-O-acetyl-6-O-benzoyl cellulose), were synthesized so that the effects of their functional group distribution on their chiral discrimination ability could be examined. Inspection of the sequences upstream of hsp26 has revealed an additional (CT)n element at -347 to -341, adjacent to the distal HSE. Postpartum depression screening in the Neonatal Intensive Care Unit: program development, implementation, and lessons learned. This is the signature of a collective effect which acts to redistribute the fluid spatially.

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In particular, there are wide variations in overall survival (OS), suggesting the existence of subgroups among N2 patients. A combination of two-time window and multiangle analysis makes detailed characterization of particle size distribution and particle aggregation feasible, which was shown using five different iron oxide dispersions. Randomised controlled trial evaluation of Tweet2Quit: a social network quit-smoking intervention. Increased health professionals awareness may improve their attitudes towards PUs prevention. This technique permits separation of molecules differing in the extent of carbohydrate branching. This article reports management of an intracanal separated instrument.

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On the basis of this information, suitable reference genes can be selected for mRNA expression studies in relevant pig tissues. Stereophotogrammetric assessment of the effect of tenoxicam on facial swelling subsequent to third molar surgery. Three minutes of acupressure was effective in decreasing pain intensity in athletes who sustained an acute musculoskeletal sports injury when measured clozaril dosage max on the VAS, but did not change anxiety levels. Achieving a successful reconstruction requires a comprehensive approach, entailing many advanced techniques with an emphasis on preserving function and balancing intricate aesthetic requirements. As a consequence, indigenous peoples are persecuted because of their traditional use of these and other plant-based narcotics and hallucinogens. Response of laryngeal airway resistance to chemoreceptor stimulation: effect of pulmonary afferent denervation. The interaction of anticancer agents with specific molecular targets can be identified by correlating target expression patterns with cytotoxicity patterns. In order to improve dye photostablity, we focused on the effect of singlet oxygen ((1)O2) generated by excited PAI probes on probe degeneration, and developed a triplet-state quencher conjugated dye probe, IC-5-T.

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The intent of this analysis is to assess clinico-pathologic and prognostic characteristics of HCC in patients with minimal liver fibrosis (Ishak stage 1-2) after primary surgical liver resection as compared to patients with moderate to severe fibrosis (Ishak stage 3-6) in order to improve screening and treatment of HCC. Imported malaria infections among Chinese labourers, returned from various countries, poses an increasing challenge to the malaria elimination programme in China. Data on patient demographic characteristics and operative results, including length of stay, blood loss, operative times, and surgical complications were collected. Macerated skin and superficial skin changes due to incontinence are associated with pressure ulcer development. Sixteen profiles were demonstrated, with one profile being predominant in samples from all the countries and species of fish. Further, we evaluate for the first time the functional effects of selective therapeutic stimulation of cardiac lymphangiogenesis post-MI.

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Insulin and leptin effects were blocked by inhibition of their intracellular effector, phosphotidylinositol 3-kinase (PI3K), by wortmannin (10 micromol) 30 min prior to insulin and leptin being given. Almost 1 year later, she presented again with markedly dilatated and reduced right heart function caused by degeneration of both biologic valves. Considering the major influence of Continental pollution and wildfire events, the spatial variability resulted in larger fine particle concentrations and higher ozone levels over the Eastern Mediterranean side in comparison to the Western one. Cerebral angiography (CAG) showed extravasation at the left frontal region. Observation of functional, meaningful activities, via DVD, has been suggested as a technique that may be effective. nov., a sulfur-inhibited thermoacidophilic archaeon belonging to the order Sulfolobales isolated from a terrestrial acidic hot spring. Ascorbic acid production was assayed directly and by way of the HMPS pathway. Trophically important phytoplankton, such as diatoms and chlorophytes exhibited seasonal trends in relative activity. Here, we constructed a T2DM-related competitive endogenous RNA (ceRNA) network (DMCN) to explore biological function of lncRNAs during the development of diabetes mellitus. We present a clinical patient with ongoing recursive angina who underwent multiple nuclear stress tests for a sequence of CAD evaluation in 26 months and demonstrated that SPECT myocardial blood flow quantitation properly guided CAD management to warrant patient outcome.

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Information about the regulation of ROCK might lead to new strategies to develop lead inhibitor compounds to modulate cardiac remodeling. Fifty patients of obstructive sleep apnea (OSA), moderate to severe cases, were randomized neurontin 100 mg into two groups of intervention: 95-percentile pressure derived from APAP titration and an optimal pressure derived from manual titration. The evolution is very variable and this is extremely disturbing for patients and their caregivers. This study evaluated maternal C-reactive protein (CRP) as a predictor of microbial invasion of the amniotic cavity (MIAC) and histological chorioamnionitis (HCA) in women with preterm prelabor rupture of the membranes (PPROM) before and after 32 weeks of gestation. Suppression of tinnitus by band noise masker--a study of 600 cases. Dietary diversity decreases the risk of cognitive decline among elderly Japanese.

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Also, more partnerships between scientists and policy makers will be required to implement these designs in light of trade-offs between scientific rigor and political realities. Diagnostic sensitivity of Tc-99m HYNIC PSMA SPECT/CT in prostate carcinoma: A comparative analysis with Ga-68 PSMA PET/CT. Role of binaural intermittent speech audiometry in differential diagnosis of neurosensory hearing disorders. A case of childhood enteric fever complicated by transient dysautonomia and cerebellitis is reported. To evaluate and compare the effectiveness of various disinfectants on Candida albicans (C.albicans) and Staphylococcus aureus (Staph.aureus) inoculated on acrylic denture base resin and effect of disinfectants on flexural strength of denture base resin. Pigeons (Columba livia) with bilateral ablation of the postero-dorsolateral neostriatum and the overlying corticoid were compared with unoperated control subjects in homing from both familiar and unfamiliar sites. One hundred thirty Alaska Natives and 115 Alaska nonnatives who underwent forensic autopsy between February 1989 and December 1993. Rikkunshito is a traditional Japanese medicine used to treat a variety of gastrointestinal symptoms.

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Comparisons were made between a group of runners who had sustained at least one overuse running injury and a group of runners who had been injury free throughout their running careers. Delayed-choice test of quantum complementarity with interfering single photons. A genetic analysis of variants of the human immunodeficiency virus type 1 (HIV-1) circulating among drug abusers in Moscow and Moscow Province. This study confirms and extends the preliminary study whereby increasing the dose of human umbilical cord blood cells we were able to substantially further increase the survival of SOD1 mice. Freshly isolated, human peripheral blood T (PBT) cells are resistant to induction of apoptosis. Fruit flies on the front line: the translational impact of Drosophila.

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The AMv projections were also examined, and the results of this investigation outline important paths that can influence hippocampal circuitry and raise new ideas for anterior thalamic-hippocampal paths involved in emotional learning. Considering the strong evolutionary conservation of early ommatidial development, homology of photoreceptor cells of distantly related insects is proposed to be inferred from their ontogenetic origin. Results from measurements with single aperture extraction systems are shown. Kaplan-Meier curves and multivariate Cox regression were used to assess the association between GTR and survival. Does surgical resection of pulmonary metastases of head and neck cancer improve survival?. It is apparent that granulocytopenia may frequently occur in patients receiving prolonged, high dose, intravenous cephalothin for the treatment of bacterial endocarditis. We used data from the baseline of a Dutch longitudinal study, relating to a population of 2,462 respondents, ages 25-74. Lamin A reassembly at the end of mitosis is regulated by its SUMO-interacting motif.

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Initially, this distinction at the neuro-physiological level has been related to the distinction between cognitive processes associated with strategic/endogenous vs. This paper describes the identification of proteins which undergo variable expression. Searching genomes for sequences with the potential to form intrastrand triple helices. Metaphase karyotypes of 6 species of the Hyrcanus Species Group of the subgenus Anopheles show constitutive heterochromatin variation in X and Y chromosomes. In spite of promising scientific progress, vaccines and therapeutic drugs are not expected to have any major impact on the global development of the pandemic during the 1990s. Total Ankle Replacement has been quite limited used currently and ankle arthrodesis is still the treatment of choice for most disabling arthritic disease of the ankle because of the generally poor long term results of ankle replacement.

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Here we report a cell type-specific TBP-related factor (TRF) that can form a stable TRF/IIA/IIB TATA DNA complex and substitute for TBP in directing RNA polymerase II transcription in vitro. Aim of this study was to report the experience on mega-prostheses implanted around the knee in tumor and revision surgery to analyze: the most frequent used current systems, the problems of stems fixation, extensor mechanism reconstructions in proximal tibia resections and the preservation of growth of the lower extremity in children. To inhibit and suppress paradoxical activation in mutant RAS cancer cells completely, it is important for RAF inhibitors to exhibit potent inhibitory activities against RAF isoforms. In contrast, remarkably high intracellular ROS levels were observed in granulocyte-monocyte progenitor cells. Determinants of the amplitude of the aortic component of the second heart sound in aortic stenosis. This study suggested that growth factor loaded stent modified by HA and heparin provided the advantage to rapid and tight restoration of endothelium. We report 18 patients who presented prior to age 20 years with epilepsy or fixed neurologic deficits.

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Indeed, the yeast model biosystem offers important advantages in the understanding of basic cellular and molecular processes. The present results are in the average of previously published results, but they have been obtained from a large single-centre cohort of patients with important reductions in the daily dose of antiparkinsonian drugs. We therefore investigated the energy metabolism and body temperature in anorectic and cachectic rats bearing the Yoshida sarcoma (TB), in comparison with pair-fed (PF) and ad-libitum fed (AL) control rats. In addition, the three-dimensional stress distribution of the abutment was analyzed by the finite element method when the magnetic attachment was removed. Likewise, little is known on gut pectinolytic bacteria and their enzyme systems. Biomarkers relevant to atacicept effects in systemic lupus erythematosus patients. Antibody-induced and cytoskeleton-mediated redistribution and shedding of viral glycoproteins, expressed on pseudorabies virus-infected cells. In this study, we present meta-analysis from published studies that have independently investigated the presence of bacteria within atherosclerotic plaque samples in coronary artery disease patients.

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