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Acyclovir is an antiviral medication that stops a protein (an enzyme called DNA polymerase) in the herpes simplex virus (HSV) and varicella-zoster virus (VZV). Without this enzyme, the virus can't make copies of itself.

Other names for this medication:
Accrivir, Acirax, Acivir, Aclovir, Acvirax, Acyclovir, Acylab, Alovir, Axovir, Cevirin, Civir, Cloviderm, Clovirax, Cycloex, Cyclopiz, Docvir, Herperax, Herporax, Herpovir, Herzovir, Kayvir, Lovir, Lyrovir, Nisivir, Ocurax, Ocuvir, Okavir, Ophtrhovir, Optiviral, Oveer, Ridoherp, Rivol, Rovir, Setuvir, Trikase, Virclo, Virex, Viroderm, Virucid, Vivorax, Zoylex

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Acyclovir (acyclovir) is an antiviral drug. Acyclovir slows the growth and spread of the herpes virus in the body.

Acyclovir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox.

Acyclovir will not cure herpes, but it can lessen the symptoms of the infection.


Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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SGI1-K, a variant of the SGI1 genomic island carrying a mercury resistance region, in Salmonella enterica serovar Kentucky. The synthetic ciguatoxin CTX3C has been shown to activate tetrodotoxin (TTX)-sensitive sodium channels (Na(v)1.2, Na(v)1.4, and Na(v)1.5) by accelerating activation kinetics and shifting the activation curve toward hyperpolarization (Yamaoka, K., Inoue, M., Miyahara, H., Miyazaki, K., and Hirama, M. Method for analyzing the compliance of quantitative characters of organisms with the hypothesis of dynamic genomic parental imprinting is developed. Poly I:C and CpG-ODN, but not imiquimod, induced significant levels of RANTES at different time-points post-treatment. The impact of air pollution on hospital admission for respiratory and cardiovascular diseases in an oil and gas-rich country. To explore early diagnosis and treatment of laryngeal burn, in order to prevent laryngeal obstruction, define the prevention of laryngemphraxis, and elect optimal time of treatment and appropriate treatment. Plants were the main source for human drugs until the beginning of the nineteenth century when plant-derived pharmaceuticals were partly supplanted by drugs produced by the industrial methods of chemical synthesis.

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Flash-induced proton release in Rhodopseudomonas sphaeroides spheroplasts. Concomitant malignancy was the major determinant of visceral artery aneurysms, both in-hospital death and survival. Racemic MDEA and its single enantiomers were incubated using heterologously expressed human P450s, and the corresponding metabolites dihydroxyethylamphetamine and methylenedioxyamphetamine were determined by gas chromatography-mass spectrometry after chiral derivatization with S-heptafluorobutyrylprolyl chloride. Influence of noise stimulation on reaction time in color perception. This study evaluated the fate of free-muscle transfer over long follow-up periods in pediatric patients. These findings underscore the need for HIV interventions among drug users that incorporate sexual risk reduction. Only a typical semiconductor laser is required as the conversion unit, where no pump or probe laser is necessary. The objective of this study was to investigate determinants of mesothelioma latency, paying particular attention to indicators of intensity of asbestos exposure such as occupation, sex, and presence of asbestosis. Di-iso-butyl phthalate (DiBP), a special plasticizer, is used what class of drug is diovan as a substitute for di(n-butyl) phthalate (DBP). The activation of mTORC1 is specific to Rheb, because other G-proteins such as KRas, RalA/B, and Cdc42 did not activate mTORC1.

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LMWH once a day had better adherence than UFH 2 or 3 times daily. In vegetative plants of Lolium multiflorum removal of the two youngest emerging leaves resulted in increased expansion of basal tiller buds. S100B levels of infants antenatally treated with GCs differed in a dose-dependent manner. An altered rotational axis resulted in significantly greater translation of the lateral compartment in the single-bundle compared with double-bundle reconstruction. The accuracy of CT and MR in the staging of renal cell carcinoma and the role of positron emission tomography (PET) scanning is outlined and finally the surveillance of patients who have had curative treatment of renal cell carcinoma is briefly addressed.

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Type and duration of exogenous hormone use affects breast cancer histology. Adenomatoid tumor is a rare neoplasm that should be added in the differential diagnosis of anterior mediastinal masses. PCR amplicons were cloned and 50 clones were randomly selected and sequenced. Additionally, we found that exposures related to poor water and socioeconomic status are more influential in the risk of infection with S. Furthermore, the ECdnT cells in this physiological context activate fibroblasts through the secretion of TGFbeta1, which, in turn, is activated by cathepsin B.

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To effectively stimulate the residual neurons in the spiral ganglion, the electrodes should be kept close to the inner wall of scale tympani. To investigate the potential of exogenously expressed CTLA4-FasL in inducing transplantation tolerance using rat cardiac graft model and its related mechanisms. The patient received postoperative radiotherapy and hormonal therapy. A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction. Because decisions regarding single vs bilateral lung transplant procedures and the need for cardiopulmonary bypass are often made based on pulmonary artery systolic pressures, we sought to examine the relationship between estimated and measured pulmonary artery systolic pressures using echocardiogram and catheterization, respectively. Supplementary Material is available online at ( Phospholipase C of an oral strain of Propionibacterium acnes purification and partial characterization. To explore the safety of performing chest percussion for patients at high risk for intracranial hypertension. Their binding to specific cell membrane receptors allows for noninvasive assessment of regional receptor proteomics in vivo. To obtain chloroplast delivery of the 43-kDa 5-enolpyruvyl 3-phosphoshikimate (EPSP) synthase of Salmonella typhimurium, we constructed fusion proteins between the bacterial EPSP synthase and the ribulose bisphosphate carboxylase small subunit.

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Cytologic studies during hormonal therapy of prostatic carcinoma. Particles are preferentially entrained into this recirculation zone, presenting the possibility of platelet activation, aggregation, and tetracycline tablets price initiation of thrombi. To correct for differences in damage inflicted on the cultivars, we developed a method to compare the attractiveness of the blends, based on the assumption that a larger amount of spider mite damage leads to higher attraction of P persimilis. Despite the asymmetrical postures seen with CD, no comparison of interhemispheric differences of pallidal local field potential (LFP) activity has been reported. Extracellular matrix specificity for the differentiation of capillary endothelial cells. Biochemical characterization of ochratoxin A-producing strains of the genus Penicillium. Technical note: preliminary communication a tridigital dynamic orthosis for tetraplegic patients. These results suggest that in the alpha 2(I) collagen promoter nuclear factor 1 and a CCAAT binding factor bind to separate sites, despite analogies in their recognition sequences.

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