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Addos (Nifedipine)
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Addos

Addos is used to treat hypertension (high blood pressure) and angina (chest pain). Addos is in a class of drugs called calcium channel blockers. Addos relaxes (widens) your blood vessels (veins and arteries), which makes it easier for the heart to pump and reduces its workload.

Other names for this medication:
Anpect, Aprical, Atenerate, Bresben, Calcheck, Cardalin, Cardicon, Carditas, Casanmil, Cisday, Duranifin, Fenamon, Jutadilat, Macorel, Nifangin, Nifecor, Nifedalat, Nifedel, Nifedical, Nifedip, Nifedipin, Nifedipino, Nifedipinum, Nifehexal, Xepalat

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Persantine, Ceclor, Ceftin, Furadantin, Rulide, Cordarone, Paxil, Differin, Acalm, Plaunazide, Benmax, Anoworm, Amitrol, Clindaval, Glycurb,

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Addos XL. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Addos dosage information

Side effects

The most common side effects associated with Addos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Primary diagnosis of foot-and-mouth disease by reverse transcription polymerase chain reaction. The combgap locus encodes a zinc-finger protein that regulates cubitus interruptus during limb development in Drosophila melanogaster. Behavioral and acoustical characteristics of the reproductive gathering of beluga whales (Delphinapterus leucas) in the vicinity of Myagostrov, Golyi Sosnovets, and Roganka Islands (Onega Bay, the White Sea). Cell surface carbohydrates such as N-acetyl-lactosamine have been postulated to mediate sorting and selective fasciculation of discrete axon subpopulations during development of the olfactory pathway. The strips of mucosa removed from the dome to produce denuded strips were also analysed by immunofluorescence using antibodies specific for vimentin and alpha-smooth muscle actin (alpha-SMA). The purpose of this review was to examine latest research findings on biomechanics of soccer kick performance and identify weaknesses of present research which deserve further attention in the future. Analyses of the stereochemistry of the 260-261 bond seen to be cleaved in this precursor structure and of the 263-264 peptide bond have suggested factors that may govern the autocatalytic mechanism. Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.

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Furthermore, we showed that the Lc-transgenic cotton plants are resistant to cotton bollworm. Diagnosis of HIV-Associated Oral Lesions in Relation to Early versus Delayed Antiretroviral Therapy: Results from the CIPRA HT001 Trial. We examined patterns of trait similarity (assortative mating) in married couples in four cultures, using both self-reports and spouse ratings on versions of the Revised NEO Personality Inventory. The digestion process of the sugar alcohol isomalt in the intestinal tract of the pig. Thus, crotamine can be regarded as a cell-penetrating peptide that, additionally, has been shown to be able of delivering some biologically active molecules into various cells.

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It is concluded that operative cholangiography is an excellent technique that will demonstrate most common bile duct stones. Distal-less induces elemental color patterns in Junonia butterfly wings. Histological and immunohistochemical results showed that the spleen and diaphragm metastases derived from thyroid follicular carcinoma. However, whether ERK plays an essential role or is implicated in all major components of cardiac hypertrophy remains controversial. The vomeronasal organ is absent, but nasopalatine ducts are present. While ChEBI is supported by a web service for programmatic access and a number of download files, it does not have an API library to facilitate the use of ChEBI and its data in cheminformatics software. Anecdotal accounts of sensory hypersensitivity in individuals with autism spectrum conditions (ASC) have been noted since the first reports of the condition. Intramedullary nails had been widely used in the treatment of long-bone fractures because of less interference of fractures and center bearing biomechanical advantage. Of 48 patients, 15 were male and 33 were female, aged 90-99 years (mean, 94.1 years).

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Pooled data collected from large studies are also presented for reference. The reovirus fusion-associated small transmembrane (FAST) proteins comprise a unique family of viral membrane fusion proteins dedicated to inducing cell-cell fusion. It is necessary for the detoxification of xenobiotics and endogenous compounds (catecholamines, steroids, bile acids), for the synthesis of structural components of membranes and tissues (sulfated glycosaminoglycans), and for the biologic activity of endogenous compounds (heparin and cholecystokinin). Cranial epidural abscesses are unusual in neurosurgical practice. Vascular smooth muscle cell synthetic capacity and viability is inhibited by lipophilic agents, whereas a hydrophilic agent does not interfere with this reparative response. Statistically significant increase of CEA-like substance in gastric juice was found in advanced atrophic gastritis (P less than 0.01), early gastric cancer (P less than 0.05) and advanced gastric cancer (P less than 0.01) as compared with normal subjects.

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Second harmonic generation reveals collagen fibril remodeling in fibroblast-populated collagen gels. Here, we summarized the latest advances made by high throughput approaches in profiling epigenetic modifications and chromatin conformations, with an emphasis on genome-wide analysis of histone modifications and their implications in pluripotency nature of embryonic stem cells. To study the effect of pretreatment with apoptotic donor spleen cells on spleen lymphocyte function of recipient rats undergoing islet transplantation to explore new approaches to prolong islet graft survival. This activity is dependent on cysteine 37 in the effector loop of Cdc42 but is not dependent on cell growth. In women not using oral contraception the largest ovary increased in volume from the start of the cycle to day 19, thereafter the volume declined. Rosuvastatin is a synthetic, hydrophilic, potent and highly efficacious statin. These decreases in hormone levels are due to serum iodine blocking the thyroid uptake of iodine and subsequent decrease of hormone synthesis. Effect of ultrafiltration process on physico-chemical, rheological, microstructure and thermal properties of syrups from male and female date palm saps. Additionally, functional predictions revealed that tissue-specific lncRNAs adjacent to protein-coding genes might play important regulatory roles in the development of floral organ and root in mulberry.

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Salivary cortisol was sampled in the home colony and during extended social separation. In the current study we show that bone marrow stroma (BMS) induces Jagged1 expression in bone metastatic prostate cancer PC3 cells and that this enhanced expression is mechanistically linked to the promotion of cell migration. Data for warfarin management after GIB should be applied with caution to direct oral anticoagulants (DOACs) because of the quicker onset and experimental nature of reversal agents. These mechanistic insights may lead to critical risk assessment and intervention in human patients. In addition, individual equations to predict METs from counts were developed from the walking data and applied to the other activities to compare the relationships between counts and energy cost. Sequence alignments of tospovirus species of serogroup I to IV revealed a stretch of 24 amino acids at the C terminus of the non-structural protein NSs with a highly conserved sequence. For example, a fourfold drop in MIC was recorded for Saccharomyces cerevisiae in MHB compared with the same organism tested in YDB. Thus, of the four measures studied, only the degraded stimulus backward masking appeared to be a specific indicator of paranoid schizophrenia.

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It is proven that variation in socioeconomic factors result in discrepancies in the use of such services. Dimensions, maximal growth sites, and optimization in the dielectric breakdown model. Refocusing and prioritizing HIV programmes in conflict and post-conflict settings: funding recommendations. Epidermis, gut epithelium, gall bladder, blood cells, spleen, thyroid gland, salivary glands, and smooth muscle cells were FA1 negative. Faecal immunochemical tests to triage patients with lower abdominal symptoms for suspected colorectal cancer referrals in primary care: a systematic review and cost-effectiveness analysis. The significance of multiple sites of relay between the efferents of the shell and the afferents of the core of the Acb at different levels of the neuraxis may be related to the functional specificity of each relay site. The purpose of this study was to assess serotonergic function in patients with major depression para que es neurontin 600 mg or mania using sumatriptan, a novel 5-HT1D receptor agonist, as a pharmacological probe in a neuroendocrine challenge paradigm. Furthermore, alterations of neuronal, endothelial, and inducible nitric oxide synthetase (nNOS, eNOS, and iNOS, respectively) were observed to correlate them with epileptogenesis.

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More generally, our study demonstrates that the combined use of optogenetics and fMRI provides a powerful new tool for evaluating computational methods designed to estimate causal interactions between distributed brain regions. After 26 weeks the protocol group showed more reduction in pain intensity than the guideline group, but this difference was absent after 52 weeks. Most ultrastructural alterations occurred between 2 and 4 hours of warm storage and there were further changes in some cells after short periods of reperfusion. The purpose of this study was to assess the influence of the depth of the intercondylar groove on patellar kinematics. Association between Toxoplasma gondii types and outcomes of human infection: A meta-analysis. Although study participants appeared to be well adjusted to spinal aygestin dose to stop bleeding cord injury, those who sustained their injury at an older age and more recently reported more negative experiences. Longitudinal analysis using generalized estimating equations was used to identify correlates of MMTP participation over time. Results were extrapolated to yield daily and yearly values of total neck motion, and that attributed to the C5-C6 level for comparison to ASTM standard F2423-05. Myocardial infarction in young vs old male rats: pathophysiologic changes.

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In contrast to the transient but strong stimulation of Ras typical of autocrine factors, activation of Ras by HBx protein was found to be constitutive but moderate. Validation procedures included assessment of discriminant and construct validity. Preliminary results of experiments with gene knock out mice which lack either alpha beta T cells or gamma delta T cells or both suggest that gamma delta T cells do not function as helper cells in humoral immune responses but may complement alpha beta T cells in the defense against various microorganisms. Results indicated that P-FU could increase the cytotoxicity of 5-FU in Hela, HepG(2) and 5-FU resistant HepG(2) cells, while it decreases the cytotoxicity of 5-FU in A549 and CT-26. This result might be explained by the higher rate of endovascular completion in the FET group.

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A model of obturation hematogenous pyelonephritis was reproduced in rats by infecting them with Pseudomonas aeruginosa. We examined whether X radiation induces a particular deletion in the mitochondrial DNA (mtDNA) of the cells of two human squamous cell carcinoma lines with different sensitivity to radiation and in a radiosensitive ataxia telangiectasia (AT) cell acticin line. The concentration of metabolic substances of the OCD group compared to the healthy control group was analyzed using two sample t-test. Results suggest that acute rehabilitation staff may need training in communicating with patients with declarative memory impairments. These conceptual models are amenable to (more or less direct) implementation on different computing platforms. Effects of combined application of culture supernatant of human umbilical cord mesenchymal stem cells and ciprofloxacin on Staphylococcus aureus in vitro. Altered expression of the Claudin (CLDN) superfamily of tight junction proteins has been reported in breast cancer.

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Acute passive vibration reduces arterial stiffness and aortic wave reflection in stroke survivors. After replacing chlorpromazine (75 mg/day) with risperidone (4 mg/day), she began to exhibit retrocollis. Test-retest characteristics of a group of attempted suicide patients. The neurocristopathies encompass genetic disorders targeting some structures originating from the neural crest development. Indeed, these vesicles can affect recipient cells by carrying and delivering complex cargos of biomolecules (including proteins, lipids and nucleic acids), protected from enzymatic degradation in the environment. 5 zithromax suspension -hydroxyindoleacetic acid (5-HIAA) levels in the cerebrospinal fluid of hydrocephalic children before and after ventricular shunting procedure.

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Milk-based formulas containing either 7.4 or 12.7 mg/L iron support normal growth and iron status of healthy, term, normally fed infants during the first year and both are well tolerated and accepted. Identification of a C-glucuronide of delta6- tetrahydrocannabinol as a mouse liver conjugate in vivo. Virion-associated RNA might be incorporated specifically or without selection during the virion assembly. Theoretically, the effect is illustrated through time dependent quantum mechanical calculations. N-acetyltransferases are the enzymes present in the cells of most mammal species.

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