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Adipex (Phentermine)

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Adipex is a medication used together with diet and exercise to treat obesity. It is taken by mouth for up to a few weeks at a time, after which the beneficial effects no longer occur. It is also available as the combination phentermine/topiramate.

Other names for this medication:
Lomaira, Phentermine, Suprenza

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Also known as: Phentermine


Phentermine is used as part of a short-term plan, along with a low calorie diet, for weight reduction. It is used in obese patients who have not been able to lose weight with diet and exercise alone. Phentermine belongs to the group of medicines known as appetite suppressants.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain phentermine. It may not be specific to Adipex. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If you take too much of this medicine, it may become habit-forming (causing mental or physical dependence).

This medicine is available in four forms: capsules, disintegrating tablets, extended-release capsules, and tablets. Carefully follow the dosing instructions for the form you are using.

Swallow the extended-release capsule whole. Do not crush, break, or chew it.

Take the disintegrating tablet with or without food. Make sure your hands are dry before touching the tablet. Place the tablet on the top of your tongue right after removing it from the bottle. It should melt quickly. After the tablet has melted, swallow or take a sip of water.

Swallow the tablet whole. Do not crush, break, or chew it.

Carefully follow your doctor's instructions for a reduced-calorie diet plan and regular exercise. Talk with your doctor before starting an exercise program.

To avoid trouble with sleeping, take the last dose of the day about 4 to 6 hours before bedtime, unless your doctor tells you otherwise.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of obesity: For oral dosage form (capsules): Adults and children 17 years of age and older—15 to 30 milligrams (mg) once a day, taken at approximately 2 hours after breakfast. Children 16 years of age and younger—Use is not recommended. For oral dosage form (disintegrating tablets): Adults and children 17 years of age and older—One tablet once a day, taken in the morning. Children 16 years of age and younger—Use is not recommended. For oral dosage form (extended-release capsules): Adults and children 16 years of age and older—One capsule once a day, taken before breakfast or 10 to 14 hours before sleeping. Children 15 years of age and younger—Use is not recommended. For oral dosage form (tablets): Adults and children 17 years of age and older— Lomaira™: One tablet three times a day, taken 30 minutes before meals. Phentermine: 18.75 to 37.5 milligrams (mg) once a day, taken before breakfast or 1 to 2 hours after breakfast. Children 16 years of age and younger—Use is not recommended.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, diarrhea, stomach cramps, sweating, blurred vision, drooling, and weak or shallow breathing.

Worsening muscle weakness, or no change in your myasthenia gravis symptoms, may also be signs of overdose.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Adipex-P dosage information

Side effects

The most common side effects associated with Adipex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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Expression of Bcl-2 family proteins in thyrocytes from young patients with immune and nonimmune thyroid diseases. Phosphorylation by neuronal cdc2-like protein kinase promotes dimerization of Tau protein in vitro. E2F1 and E2F7), and consequently to have a better understanding of their role in cell cycle processes. The aim of the study was to successfully design, formulate and evaluate self-nanoemulsifying drug delivery system (SNEDDS) of poorly aqueous soluble drug viz. It was possible to observe a fraction of variance associated in different ways with water. We investigated the production of soluble mono- and bivalent single chain antibodies (scFv) in eukaryotic cells and describe a cassette vector system for mammalian and baculovirus expression which is compatible with an established vector system for bacterial expression and phage display selection of scFvs. Sixty women with urinary incontinence were treated by the Burch colposuspension operation and bladder neck plication.

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This is a single-center retrospective cohort study including all consecutive patients who were hospitalized for severe sepsis or septic shock between March 2006 and September 2014 and who underwent coronary angiography in the intensive care unit to identify AMI. Two predictors (ProA-SVM and ProA-RF) using selected features are built for predicting peptide aggregation propensity and identifying aggregation prone regions in proteins. Therefore, MNT can be applied for the early detection of oral carcinoma in the human being. Tuberculosis in poorly controlled type 2 diabetes: altered cytokine expression in peripheral white blood cells. In addition, pretreatment with the protein kinase C inhibitor 1-(5-isoquinoline sulfonyl)-2-methylpiperazine prevented the ATP-mediated inhibition. Development of curly hair has been infrequently described in association with BRAF inhibitors in clinical trials, and usually affects patients between 6 and 24 weeks of therapy. A century of genetic analysis has revealed that multiple mechanisms control the distribution of meiotic crossover events. The objective of this study was to explore the prevalence and correlates of self-reported sitting time in adults across and within the 28 European Union Member States.

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Therefore, the spontaneous emission can be solved by conventional Weisskopf-Wigner approximate theory, which yields a pure exponentially decaying behavior with a rate proportional to the LDOS. Long-term care for older Americans: the institutionalization of senescence. A 38-year-old woman with metastatic malignant struma ovarii, including massive liver metastases and retroperitoneal lymphadenopathy, underwent ovarian resection and retroperitoneal lymph nodes excision, partial hepatectomy, and radiofrequency ablation for liver metastases. The aim of this study was to identify pathways of the efferents of the shell of the Acb to influence the outflow of the core of the Acb. Brain morphology, dopamine, and eye-tracking abnormalities in first-episode schizophrenia. We aimed to investigate if decreased portal vein (PV) velocity is associated with future PVT. Effect of hyperbaric oxygen therapy combined with autologous platelet concentrate applied in rabbit fibula fraction healing. The thromboplastic potency of different morphological parts of rabbit brain.

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Synthesis of Cyclic Imides (Methylphtalimides, Carboxylic Acid Phtalimides and Itaconimides) and Evaluation of their Antifungal Potential. It causes transient atrioventricular nodal block and thus ends paroxysmal supraventricular tachycardias that involve the atrioventricular node. The goal of this study was to review our series of percutaneous nephrolithotomy (PNL) to evaluate the success rates and present the key technical points to achieve a successful outcome. Incidence of chronic hepatitis after epidemic of infectious hepatitis. A total of 239 dogs were included and randomly allocated in a 1:1 ratio to receive either robenacoxib or placebo. A high proportion of participants presented indicators of social disadvantage and other risk factors previously associated with depression worldwide.

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The administration of human menopausal gonadotrophin (HMG) followed by human chorionic gonadotrophin (HCG) stimulated the development of various numbers of follicles in patients treated for infertility. It focuses on capacities and preconditions for principle-based reflection and action by arguing that moral perception and certain emotional qualities are prerequisites for moral judgment and action. Phosphorylation of RB by CDKs neutralizes its cell cycle inhibitory properties, allowing progression of G1 to S phase. We have not only developed a new approach to map global Cys-redoxomic regulation in vivo, but also provided new evidences implicating Cys-redox modifications of key molecules in NO-mediated ischemic cardioprotection. Nevertheless, the following patterns can be identified: In general, both the incidence and prevalence of OA of the hip and knee increase with age. Ischemic contractures of lower extremities in children and adults. No other urological or extra-urological congenital defects were found.

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The role of scientific societies in addressing the threats of emerging infections: summary of roundtable discussion. Immunohistochemical analysis and in situ hybridization showed that both ECP40 and its transcripts were preferentially localized in the peripheral cells of the clusters of embryogenic cells. The combination of clinical utility and quality improvement tools facilitates delivery of quality ADHD care and reduces several of the obstacles to implementing AAP-recommended practice behaviors. The elucidation of the mechanism of subcellular targeting of GAD may be relevant to understanding its role as an autoantigen. Prolonged therapeutic hypothermia is more effective in attenuating brain apoptosis in a Swine cardiac arrest model. When region-specific results were combined, no statewide association was apparent.

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The evaluation of auditory function in homozygous sickle cell disease. Among these, abiotic environmental factors and biotic processes are often favoured. Mdx mice exhibited thickening of colonic smooth muscle layers and delayed stress-induced defecation. Although the questions are domain-specific, they are asked by non-professionals, making the question classification task more challenging. The effects of study-test lags of between 0 and 32 items on conscious (C) and automatic (A) memory processes in a running word-completion task were investigated with event-related potentials (ERPs).

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Research sample comprised 40 clinically treated hyperuricemic patients of both sexes, different ages, classified into several subgroups according to the disease diagnoses. The reduction in EELV in stage R sleep was associated with lower mean oxygen saturation but was not associated with greater sleep-disordered breathing. This simple approach promises to resolve the technical difficulties in targeting DNA sequences with PNA. Mental stress provokes myocardial ischemia in many patients with stable coronary artery disease (CAD). The eubacterial CADs are found in metalloproteases, while CAD-containing proteins in the archaebacterial and eukaryotic lineages appear to have diversified by a series of gene duplication events that lead to the establishment of different functional AAA proteins, including proteasomal regulatory, NSF/Sec, and Pas proteins. Most articles are case reports or are data from adult and pediatric registries. Evaluation of the AxSYM homocysteine assay and comparison with the IMx homocysteine assay.

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Results of serological investigation and of provocation challenge indicated a hypersensitivity pneumonitis due to allergens of Micropolyspora faeni. The effectiveness of the UVB at 296 nm and UVC at 266 nm irradiations was quantified by counting colony-forming units. A Systematic Review of the Prognostic Role of Hematologic Scoring Systems in Patients With Renal Cell Carcinoma Undergoing Nephrectomy With Curative Intent. Crossover events are associated with DNA sequence motifs, together with an open chromatin signature (hypomethylated CpGs, low nucleosome occupancy or specific histone modifications). To observe the effect of electro-acupuncture (EA) on dendritic spine and ephrin-A5 and to investigate the action of EA on neural plasticity after acute cerebral ischemic infarction. P.A.S.Port insertion is a safe outpatient procedure and is an alternative for permanent venous access. The deposition of alternating layers of sulfonated polyaniline and cyt c was carried out by adsorption from the corresponding solutions on a cyt c monolayer electrode.

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The N-heptad repeat (N-HR) of gp41 is the site of action of two classes of inhibitors. After rapid thawing and serial dilution to remove DMSO, individual islets were prepared with AO/PI stains for imaging on the LSCM. For example, although Au has been previously measured in plant samples, there has been doubt as to whether it was truly absorbed rather than merely adsorbed on the plant surface as aeolian contamination. This review has been conducted according to the PRISMA statements. The objective of this study was to evaluate physical activity (PA) levels in adults and their association with sex, age, and education level across categories of body mass index (BMI). These results were then compared with the results that were obtained by quantifying apoptosis in 6 first-trimester placental samples with transmission electron microscopy. Several important aspects of the drug discovery process, including target identification, mechanism of action determination and biomarker identification as well as drug repositioning, require complete understanding of the effects of drugs on protein phosphorylation in relevant biological systems. The objective of the study was to analyze the effects of iv lipid and heparin infusion on circulating androgen levels in healthy women. After 1 hour of CPB and 1 hour of spontaneous reperfusion, horseradish peroxidase was injected intravenously and circulated for 15 minutes. The morpholinyl and piperidyl amides react 2.5 times more rapidly with factor Xa.

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In these patients, no other acute side effects of pentamidine were observed. At necropsy degenerative changes were most prominent in the neurons of the red nuclei, brain stem structures which modulate motor function. A cross- sectional study was undertaken with data collected through standardised procedures from consenting athletes under 21 years of age. Many how many mg of zyrtec can you take while pregnant young Australian women are failing to meet key nutrient targets as nationally recommended. R6 and R7 alleles of potato conferring race-specific resistance to Phytophthora infestans (Mont.) de Bary identified genetic loci clustering with the R3 locus on chromosome XI. A chamber attached to the SEM for fracturing and coating frozen biological samples. Elimination efforts should be intensified among women of Yoruba ethnicity.

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Here, we explore the effects of nanoscaling on the memory-storage capability of self-assembled Ge2Sb2Te5 nanowires, an important phase-change material. Hematological and biochemical dynamics in patients with cancer of the uterine cervix studied from the standpoint of the liver function tests. The current map is the most saturated map for black gram to date and will provide a useful tool for identification of QTLs and for marker-assisted selection of agronomically important characters in black gram. Our method is thought to be useful for accurately evaluating intratumoral gene expressions. The formal conditions of the treatment were comparable in both groups. For the lagged cells, the largest response increase occurred for the initial part of the visual response. Cytochrome P450s (CYPs), UDP-glucuronosyltransferases (UGTs) and sulfotransferases (SULTs) are the most important enzymes for metabolic clearance. Human reproductive cloning provides the possibility of genetically related children for persons for whom present technologies are ineffective.

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Since this is a fairly unexplored research field, more research is needed to explore the role of macroeconomic conditions for various health outcomes, long-term implications and gender differences. All providers reported that they do not optimally use integrative therapies for children with SCD. The effect of the therapy was assessed and the problems with it analyzed by interviews with the subjects and the results of International Index of Erectile Function (IIEF) before and after the treatment. We hypothesized that the results of spirometry between smokers of the two races are equivalent if reference equations and lower limits of normal appropriate for each race are used. Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15. Data on the comparative efficacy of fulvestrant and other endocrine treatments are inconsistent. The authors summarise different guidelines, experiences, indications and problems in hemotherapy concerning bleeding complications.

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Morphometric analysis showed that kidney weight, glomerular volume and glomerular capillary radius were lower in nifedipine treated rats than in the other two groups, indicating that the CEB, but not enalapril, inhibited the hypertrophic response to ablation of renal mass. In contrast, the increment in blood flow associated with pentagastrin-stimulated acid secretion was significantly greater in the gastric mucosa than in the extramural artery. However, little is known about the prevalence of GERD in dialysis patients. It was discovered in a 29-year-old female who complained of a painful swelling in the right generic zantac recall 2020 frontal region. A differentiation model was established by pooling all valuable parameters together.

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Genes known to be coordinatively regulated in response to growth arrest and DNA damage, GADD45 and GADD153, were induced compared to the housekeeping gene beta-ACTIN by equitoxic doses of hydrogen peroxide and mercaptosuccinate. Acute abdomen caused by torsion of the pedicle in a wandering spleen. To investigate the relative value of the use of open-ended and structured questionnaires in the determination of the most appropriate management of patients in a busy audiological rehabilitation clinic. Few studies have focused on the prognostic role of VUC in non-muscle-invasive bladder cancer (NMIBC). Neuropsychological rehabilitation in the treatment of schizophrenia. The copper vapor laser is a useful addition to the family of lasers that are used for cutaneous conditions. LOSITAN: a workbench to detect molecular adaptation based on a Fst-outlier method. Compared to the controls, obese juveniles had a significantly decreased ratio between high molecular weight (HMW) and total adiponectin whereas the LMW/total adiponectin ratio was increased. Three of the 4 systematic reviews used rigorous appraisal methods. beta cell function and insulin sensitivity were calculated from the fasting plasma glucose and insulin concentrations with homeostasis model assessment.

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The mRNA and protein expression level of tight junction components with IL-8 under different concentration and duration was examined by RT-PCR and Western blot, respectively. Developing Techniques and Strategies for the Management of Cancer Pain. Between February 2004 and October 2005, premature CAD patients, defined as those younger than 50 years of age, who were treated with DES in our medical center were all retrospectively enrolled. A total of 300 participants were studied during a 3-year period in an attempt to partially replicate and further expand a previous study conducted in Greece among CHD patients, which indicated a strong association between certain dimensions of Emotional Intelligence and the incidence of CHD. Doppler tissue imaging was performed in 12 left ventricular (LV) segments in 24 children with DCM and 19 controls. Renal function should be closely monitored, especially in patients who exhibit decreasing eGFR, DM, and the use of diuretics. All notifications of HA ILI outbreaks between July 2001 and June 2015 were included. WS is caused by inherited recessive mutations in the WRN gene, which encodes a helicase considered a caretaker of the genome.

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Endothelin receptors stimulate both phospholipase C and phospholipase D activities in different cell lines. 16S ribosomal deoxyribonucleic acid (rDNA)-based denaturing gradient gel electrophoresis (DGGE) and terminal restriction fragment length polymorphism (T-RFLP) molecular fingerprinting methods were used to track the succession of microbial communities in summer and winter composting cycles. It prompted the development of nonablative lasers and non-laser systems, which stimulate dermal neocollagenesis without epidermal disruption, and therefore, produce less adverse effects with little or no healing time. We examined the associations of fetal blood flow redistribution with birth outcomes, and repeatedly measured fetal and childhood growth and fat mass measures. Moreover, prolonged IL-1beta or TNF-alpha treatment activated double-stranded RNA-activated protein vantin antibiotic dosage kinase (PKR). It might be a very practical method for the treatment of these surgical complications in hospitals where advanced treatment modalities are not available. Differences in preterm delivery rates and outcomes in Jews and Bedouins in Southern Israel. Because one of all optical pathways to induce Fano effect refers to the generation of quantum entangled states, It is shown that the concurrence of quantum entanglement can be obtained by observation for Fano effect. The prevalence of HHT in the Leeward Islands of the Netherlands Antilles is possibly the highest of any geographical location.

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Physical capacity of patients with tuberculous spondylitis and neurological disorders which had started in childhood. This air-licking is attenuated by experimental manipulations which reduce the evaporative cooling of the tongue and mouth produced by the airstream. Sales tax data for 15 cities with smoke-free restaurant ordinances, 5 cities and 2 counties with smoke-free bar ordinances, and matched comparison locations were analyzed by multiple regression, including time and a dummy variable for the ordinance. This paper reports the occurrence of bilateral hemianopia in a 16 year old male who was having unusual seizures accompanied by severe migrainous headaches and loss of singulair medicine make you sleepy vision while watching a television programme and while playing with the computer. In several species, recently inseminated females exposed to a strange male will lose developing embryos. Together these results stress the importance of Fgf signaling in the adult brain and establish the basis to study its function in zebrafish, in particular in relation to adult neurogenesis. When serum samples are preincubated with buffer a loss of activity was observed in 4 out of the 6 AMP buffers. The investigation revealed target segments of osteoarticular apparatus (jaw, vertebral spine, shoulders, elbows, hands and fingers, lower limbs) electively subjected to overuse, as well as muscle contracture of trapezoids and hyperkeratosis of fingers and clavicle.

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The morphological differences among Paranthropus, Australopithecus, and African early Homo as studied here are small and evolutionarily less significant compared to the differences between the earlier and later homin taxa. Biosynthesis of (plus)-protolichesterinic acid in Cetraria islandica. Effects of carboxymethylcellulose (CMC)-based artificial saliva in patients with xerostomia. While insect wings are widely recognised as multi-functional, recent work showed that this extends to extensive bactericidal activity brought about by cell deformation and lysis on the wing nanotopology. It is uncertain how these postnatal phenomena, which suggest an interrelationship with cardiopulmonary adaptation, are brought about. An efficient numerical solution based on the classical alternating direction minimization method (ADMM) is tailored to solve the proposed model. This report presents one particular model of action of interleukin-6, that can open new insights for a deeper understanding of the relationships between interleukin-6 and different ion channels into the fibroblast.

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