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Admadol (Tramadol)

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Admadol is a narcotic-like pain relieving oral medicine that is used as a treatment for moderate to severe pain in adults. This medication must be prescribed by a doctor and is available by prescription only.

Other names for this medication:
Acupain, Admadol, Anatram, Armadol, Atdol, Avdol, Axedol, Combitram, Contramal, Cormadol, Cradol, Decotram, Didol, Dolex, Dolotram, Euphodol, Midol, Muzox, Orchidol, Oshdol, Ramax, Stemadol, Taxidol, Tolydol, Topspas, Tradol, Tramache, Tramacon, Tramak, Tramakind, Tramatas, Tramataur, Tramazac, Tranzat, Trofel, Trugesic, Trydol, Unidol

Similar Products:
Seroquel, Neoral, Noroxin, Ilosone, Parlodel, Lanoxin, Biaxin, Rizatriptan, Gentipress, Megestone, Nupam, Fexamin,

Also known as: Tramadol


Admadol ER is an pain medicine similar to an opioid. This medicine is used to treat moderate to severe pain.

The extended-release form of tramadol is for around-the-clock treatment of pain. This form of tramadol is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Admadol: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Admadol is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Admadol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Admadol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how Admadol ER will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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A blinded observer was asked to identify the position of the tube within six breaths using impedance respirometry. Conversely, a clear correlation between neurophysiological pattern and symptoms was not found. Investigations of in vivo methionine racemization in mammalian tissues. In the case of the novel technique herein described, the dura mater is preserved in a new manner. The analyses were replicated in a population of 27,668 Swedish twin pairs, 45-108 years of age.

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To determine the relationship between change in physical activity level and change in directly measured maximal aerobic fitness in severely obese subjects participating in a 1-year lifestyle intervention, and to determine whether change in 6-min walk test (6 MWT) could be used as an indicator of change in aerobic fitness. For every independent source, we are able to determine the electrode potentials evoked by every dipole separately by the projection of independent activation maps back onto the electrode arrays. Rates of adverse events detected by medical record review and clinical incident and general practitioner reporting. Whether enzyme replacement therapy is effective in all stages of Fabry cardiomyopathy during long-term follow-up is unknown. Methylnitrosourea at a dose of 10 mg/kg is teratogenic when applied to pregnant mice on gestational days 2.5, 3.5 or 4.5, but has no such effects on gestational days 0.5 and 1.5.

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Serum Tg--a sensitive marker of thyroid abnormalities and iodine deficiency in epidemiological studies. Previous reports have indicated a small, positive relationship between physical activity and cognition. The shift magnitude is in good agreement with quantum-chemical calculations. As shown by several studies, dialysis-dependent patients are at especially high risk for medication-related problems. Chlamydia trachomatis sigma28 recognizes the fliC promoter of Escherichia coli and responds to heat shock in chlamydiae. Systematic analysis of aphid populations and niches patterns on spring sowing maize was carried out during 1998-1999 in the suburbs of Chongqing. In addition, it is proposed that modulation of the reflex by AVT occurs in part by shortening the duration of the sensory neurone action potential. Aspiration fine needle and cutting biopsy cannula in an experimental comparison. These features define a phenotype that corresponds to the recently described protease-sensitive prionopathy (PSPr).

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This work investigated the effect of HSP90 inhibitors on cultured OPCs. Real-time PCR and immunohistochemistry were used to detect the expression of caveolin-1 in 123 specimens of HCC tissues obtained during operation. The cytokine macrophage migration inhibitory factor (MIF) is produced by neuroendocrine and immune tissues and possesses several features that allow it to be characterized as a neuroendocrine mediator. MF101 also selectively regulates transcription of endogenous genes through ERbeta. The thermal stability at 37 degrees C of several clinically relevant enzymes and isoenzymes was assessed by measuring changes in enzyme activity as a function of time under incubation and reaction conditions. Therefore, the PoO seems to be the pontine micturition inhibitory area. Quantitative analysis of the changes in the nuclear apparatus of thyrocytes in experimental thyroid hyperfunction. Smokeless tobacco and cardiovascular disease in low and middle income countries.

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Elevated serum levels of TARC/CCL17, eotaxin-3/CCL26 and vascular endothelial growth factor in a patient with non-episodic angioedema associated with eosinophilia and granulomatous cutaneous reaction. For many patients, the initial prescription is only the beginning of the prescribing process, with the prescription needing to be repeated, sometimes for the life of the patient. Production of ESBL was investigated by testing resistance against ceftazidime, cefotaxime, ceftriaxone and verified by Double Disk Synergy Test. In contrast, expression of DNrasB slightly delayed the initiation of germination and caused the development of conidiophores in submerged culture. v-Rel-transformed cells exhibit elevated RNA and protein expression of c-Fos, c-Jun and ATF2 and sustained repression of Fra-2. pylori-positive patients were randomized to receive omeprazole, 20 mg b.i.d., clarithromycin 500 mg b.i.d., and either amoxicillin 1 g b.i.d. Angiotensin-converting enzyme inhibitors are widely used in medicine because of their antihypertensive and antifibrogenic effects.

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Protection against cellular stress by 25-hydroxyvitamin D3 in breast epithelial cells. Metabolism of 2-ethyl-2-methylsuccinimide (ethosuximide) in the rat and human. Acetylation modifications are mediated through histone acetyltransferases (HAT) and deacetylases (HDAC), and the balance of these enzymes regulates neuronal homeostasis, maintaining the pre-existing acetyl marks responsible for the global chromatin structure, as well as regulating specific dynamic acetyl marks that respond to changes and facilitate neurons to encode and strengthen long-term events in the brain circuitry (e.g., memory formation). Pregnant women with psoriasis may be at increased risk for adverse pregnancy outcomes due to comorbidities or other health behaviours associated with the disease. Two studies were completed that focused on instrumentation and procedural issues associated with measurement of lingua-palatal contact pressure (LPCP) during speech. Foreign bodies were introduced in the gallbladder of the guinea pig in order to study their effect on the cell proliferative parameters in the gallbladder mucosa. Significant correlations were found between Ang I and Ang II as well as between Ang II and Ang-(1-7) in the different study group distributions. The degree to which these results will translate to the clinical environment remains to be established, but the pattern of subtle elevations in inflammatory cytokines indicated both a mild persistence of responses to PEEK debris, and that intradiscal implant debris will likely result in less inflammation than epidural implant debris. Unless distant metastases or local invasion are present, the diagnosis of malignant pheochromocytoma is challenging.

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To investigate the effects of heliox on peripheral O(2)DEL and utilization during exercise in moderate to severe COPD. Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat. Occurrence of Giardia cysts and Cryptosporidium oocysts in swimming pools in the province of Palermo, Italy. Anopheles persiensis was collected only in the northern Caspian Sea littoral provinces of Gilan and Mazandaran, and it seems likely that this species could be responsible for malaria transmission in this region that was previously attributed to A. CHD status was assessed via standard history and resting electrocardiogram in 41 postmenopausal diabetic and 41 age- and body mass index-matched normoglycaemic women recruited from a community-based cohort. Results were consistent with classical autosomal recessive inheritance in the case of cystinosis and X-linked inheritance for Fabry disease, confirming that this family represents an example of two rare disorders occurring in the same sibship. A further point of difference between novel and group A rotaviruses is their genome profiles, which lack the triplet of segments in the 7-8-9 region of group A rotaviruses. In the present study, an antibody for (di)bromotyrosine in proteins was prepared to investigate the pathogenesis of eosinophil-related diseases such as allergic responses. Probing of the target molecules of Rho-kinase and its function in neuronal cells.

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The Ontario Farm call Surveillance Project (OFSP) was a practitioner-based, syndromic surveillance system for livestock disease. The histopathologic diagnosis on 4 cases was benign fibroepithelial polyps of ureter. Sixty day care centers (DCC) randomly selected from 736 licensed child care facilities in Harris County (Houston), Texas were surveyed for the incidence of diarrhea by periodic visits and weekly telephone calls over two years. The purpose of this study was to compare demographics, resources used, and mortality rates among a subset of trauma patients (blunt versus penetrating) who developed adult respiratory distress syndrome (ARDS) and over two time periods, 8 years apart. The materials and the reagents are also affordable and they are available locally. Four hundred forty-three climbers (273 men, 170 women) from 55 countries participated in 3 separate disciplines totaling 520 climbing days. The management of advanced squamous cell carcinomas of the head and neck has shown disappointing results with surgery and radiation alone.

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Animals fed LT with OVA after the initial OVA prime developed a significantly lower serum IgG and mucosal IgA anti-OVA response than those fed LT with OVA in the initial immunization, indicating that prior exposure to the antigen reduces the effectiveness of LT to influence tolerance and its ability to act as an adjuvant. In model experiments on human genomic DNA, we demonstrated that DSN normalization of double-stranded DNA formed during C0t analysis is effective against abundant repetitive sequences with high sequence identity, while retaining highly divergent repeats and coding regions at base-line levels. Regulated trafficking of neurotransmitter receptors is critical to normal neurodevelopment and neuronal signaling. The necrotic phase preceded apoptosis, although these did show an overlap. The incidence of inguinal hernia is clearly increased in men who have undergone radical retropubic prostatectomy plus pelvic lymph node dissection compared with those who undergo no surgery for prostate cancer. Hematologic and neurologic consultants were initially considered purely hematologic or neurologic diagnoses.

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The histopathology of clinical isolates of Scedosporium apiospermum, Scedosporium boydii, and Scedosporium aurantiacum in immunosuppressed mice was evaluated. A mathematical approach to predict the affinity of estrogen receptors alpha and beta binding to DNA. Surgical management of multiple posttraumatic arteriovenous fistulas of femoral vessels. Data are unavailable in the era of drug-eluting stents, dual antiplatelet therapy, statins, and modern medical therapy. This chapter summarizes the new paradigm for arterial thrombosis. Algorithms are not intended to be final diagnostic answers on any given case. Effect of kallikrein-kinin system on calcium-vitamin D3 metabolism.

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HDLs protect the MIN6 insulinoma cell line against tunicamycin-induced apoptosis without inhibiting ER stress and without restoring ER functionality. Reliability of erector spinae oxygenation and blood volume responses using near-infrared spectroscopy in healthy males. The duration of acute cough in pre-school children presenting to primary care: a prospective cohort study. A data augmentation scheme with latent binary cure indicators is adopted to simplify the Markov chain Monte Carlo implementation. Insulin resistance plays a major aetiological role in the development of fatty liver disease. Following four unsuccessful IVF or IVM cycles, 15 months after the last cryopreservation, six fertilized oocytes were thawed for a scheduled embryo transfer. This study highlights the occurrence of metabolic abnormalities with both stavudine and tenofovir DF treatment. It is likely that the study of the interplay of growth factors, and the molecular basis of pleiotropic effects elicited by growth factors, will help to explain how growth factor-signaling pathways affect gene expression and cell division in normal and transformed states. The diagnostic criteria for nonerosive reflux disease (NERD) and functional heartburn (FH) have been changed.

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Blood stream infections during chemotherapy-induced neutropenia in adult patients with acute myeloid leukemia: treatment cycle matters. Children identified on the basis of language impairment show significant motor comorbidity. These results suggest, apparently for the first time, that high-sugar diets appear to induce mitochondrial dysfunction in adipose tissue, which may be related to greater weight gain and metabolic impairment. Moreover plasma MT-I levels in zinc-deprived rats given endotoxin were only slightly greater than those in untreated rats of normal zinc status. Analysis of the data collected was performed based on diagnosis, cause of extraction of the natural tooth, location, period of implant placement, implant surface, and treatment approach. In addition to stenosis of the porcine valve, formation of thick fibrous neointima plays a major role in the pathogenesis of conduit obstruction.

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The conserved hydrophobic motif at the C-terminal extension of the kinase domain is bound to the N-terminal lobe of the kinase domain, despite being unphosphorylated. Incorrect vector after calibration of surgical instruments for image guidance. These results demonstrated that F12 is a functioning hybrid cell line of the first-order suppressor T cell benicar 40mg tablets subset. Evidence that micronutrient malnutrition increases late onset diseases, such as cancer, is discussed. The RT-PCR assay detected the enterovirus in the groundwater sample collected on 26 September 1998. Each 2-hour transect of the adhesive tape from the trap was examined by immunoblotting and by normal light microscopy to compare antigen particle counts with grass-pollen counts. It is argued that whether LI emerges depends on the behavioral measure used to index conditioning. Chest pain is one of the chief presenting complaints among patients attending Emergency department. Therapy was not what I expected: a preliminary qualitative analysis of concordance between client expectations and experience of cognitive-behavioural therapy. Meanwhile, detoxification of hydrogen peroxide by catalases has been proposed as a way to overcome this host response.

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