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Aldbest (Montelukast)
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Aldbest

Aldbest is an inexpensive drug used to treat asthma. It is also used to treat allergies. It is slightly more popular than comparable drugs. It is available in generic and brand versions. Generic Aldbest is covered by most Medicare and insurance plans.

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Also known as: Montelukast

Description

Aldbest (montelukast) is a leukotriene (loo-koe-TRY-een) inhibitor. Leukotrienes are chemicals your body releases when you breathe in an allergen (such as pollen). These chemicals cause swelling in your lungs and tightening of the muscles around your airways, which can result in asthma symptoms.

Aldbest is used to prevent asthma attacks in adults and children as young as 12 months old. Aldbest is also used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs) in adults and children who are at least 6 years old.

Aldbest is also used to treat symptoms of year-round (perennial) allergies in adults and children who are at least 6 months old. It is also used to treat symptoms of seasonal allergies in adults and children who are at least 2 years old.

Aldbest is used for allergies, only after other treatments have failed.

If you already take Aldbest to prevent asthma or allergy symptoms, do not use an extra dose to treat exercise-induced bronchoconstriction.

Dosage

Usual Adult Dose of Aldbest for Allergic Rhinitis:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose of Aldbest for Asthma -- Maintenance:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose for Bronchospasm Prophylaxis:

-10 mg orally once a day at least 2 hours before exercise Comments: -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB)

Usual Pediatric Dose of Aldbest for Asthma -- Maintenance:

Less than 12 months: Not approved. 12 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet or one sachet oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Doses should be taken in the evening. -Efficacy has been demonstrated for asthma when this drug was administered in the evening without regard to time of food ingestion. Use: Prophylaxis and chronic treatment of asthma in pediatric patients 12 months of age and older

Usual Pediatric Dose of Aldbest for Allergic Rhinitis:

Seasonal Allergic Rhinitis: Less than 2 years: Not approved. 2 to 5 years: -4 mg chewable tablet or one sachet of 4 mg oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Perennial Allergic Rhinitis: Less than 6 months: Not approved. 6 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet orally once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -The time of administration may be individualized to suit patient needs. Uses: -Relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older -Relief of symptoms of perennial allergic rhinitis in patients 6 months of age and older

Usual Pediatric Dose for Bronchospasm Prophylaxis:

Less than 6 years: Not approved. 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Dose should be taken at least 2 hours before exercise. -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older

Detailed Aldbest dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aldbest are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take the Aldbest if you are allergic to Montelukast or any of the other ingredients of this medicine. Do not use the tablets to treat an acute asthma attack, including Status Asthmaticus. Do not use the drug if you suffer from severe kidney failure. Do not combine the medication with drugs which induce the CYP450 enzyme system (phenobarbital and rifampin), as they may decrease the effects of Montelukast. Do not use the medication if you have a phenylketonuria, as Aldbest contains phenylalanine. Do not take the medication tablets during pregnancy or while breastfeeding without consulting your doctor. Avoid drinking alcohol while taking Aldbest tablets, as it may cause excessive drowsiness. Do not give this medicine to children less than 2 years of age.

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The in vitro drug interaction potential of dietary supplements containing multiple herbal components. In cells with reduced levels of endogenous ARAP2, FAs and SFs could be restored with wild-type recombinant ARAP2 but not mutants lacking ArfGAP or Rho-binding activity. In vitro proguanil activation to cycloguanil is mediated by CYP2C19 and CYP3A4 in adult Chinese liver microsomes. Developmental PCB exposure is associated with immunotoxic effects on serum coreg to metoprolol conversion dose concentrations of specific antibodies against diphtheria and tetanus vaccinations. In addition, their automation and haemoglobin quantification allows a threshold for colonoscopy to be selected that can be accommodated within individual health care systems. Differentiated staging in the determination of regional lymph node involvement in breast cancer.

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The results demonstrate the poor reproducibility among experts of the pathological diagnosis of primary liver carcinomas with fibrous stroma in patients who did not have cirrhosis, and highlight that the systematic use of immunohistochemistry may improve the diagnostic accuracy. To determine whether similar regulatory mechanisms operate in the ancient gymnosperm Ginkgo biloba, we measured Lhcb mRNA levels in seedlings in response to different light conditions. The results suggest that in obese children nutritional-behavior interventions may reduce the liver fat. Two major routes for membrane lipid transport are recognized: vesicular trafficking and lipid transfer at zones of close contact between membranes. It has been previously shown that sera from chagasic patients have an antibody specific for beta adrenoceptors, independently of other tissue-reactive antibodies as the EVI (endocardium, blood vessels, interstitium) system, and it is highly specific to other heart diseases. Successful treatment depends on a thorough evaluation and understanding of this dentofacial deformity. Inhibition was observed exclusively for proteins translocating into or across the inner membrane but not for proteins residing in the outer membrane or the intermembrane space.

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