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Alendix (Alendronate)

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Alendix is used to treat and prevent osteoporosis (a condition in which the bones become thin and weak and break easily) in women who have undergone menopause and to treat osteoporosis in men.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Omnicef, Avelox, Caverta, Minocin, Lunesta, Cleocin, Magnabiotic, Tenoric, Gastrodom, Soflene, Methocarbamol, Shinun, Nebivas, Zisper,

Also known as: Alendronate


Generic Alendix is a drug which helps to fight with postmenopausal osteoporosis, steroid-induced osteoporosis, Pagets disease of bone. Generic Alendix is a medicine which belongs to the group of medicines called bisphosphonates. Alendix is also known as Alendronic acid, Alendronate sodium, Ostofos. Generic Alendix works by preventing bone breakdown and increasing bone density (thickness). Generic name of Generic Alendix is Alendronate. Brand name of Generic Alendix is Alendix.


Take Alendix exactly as prescribed by your doctor. Alendix is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Alendix first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Alendix tablet. Swallow the tablet whole.

For at least 30 minutes after taking Alendix:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Alendix. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Alendix is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Alendix is often given for only 3 to 5 years.

Detailed Alendix dosage information


If you overdose Generic Alendix and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Alendix overdosage: heartburn, stomach pain, diarrhea, numbness, tingling, tight muscles in your face, irritability, unusual thoughts or behavior, nausea, muscle cramps, convulsions.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alendix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Alendix if you are allergic to Generic Alendix components. Be very careful with Generic Alendix if you are pregnant or planning to have a baby, or you are nursing mother. Generic Alendix can harm a baby. Be careful with Generic Alendix if you suffer from or have a history of low blood calcium (hypocalcemia), a vitamin D deficiency, kidney disease, an ulcer in your stomach or esophagus. Be careful with Generic Alendix if you are taking aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Naprosyn, Aleve); cancer chemotherapy; or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Do not stop take it suddenly.

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It is shown that the observed Vogel-Fulcher-Tammann (VFT) dependence of the dc conductivity can be traced back to a similar temperature dependence of the mobility while for the number density an Arrhenius-type thermal activation is found. The Mitochondrial Protein Atlas: A Database of Experimentally Verified Information on the Human Mitochondrial Proteome. Moreover, FCS values of the right hippocampus and the left temporal pole were positively correlated with the cognitive performance in aMCI. Persistent Rule-Following in the Face of Reversed Reinforcement Contingencies: The Differential Impact of Direct Versus Derived Rules. In this study, we describe the color Doppler imaging findings in carotid body tumors and vagal body tumors.

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Future research should focus on the role of wrist movements and compensatory movements in the development of MSCs in individuals with FPHAs. Refractory chronic spontaneous urticaria associated with CD4 lymphocytopenia in a patient with thymoma. Through announcement of their case the authors want to call the attention to the importance of the DNA-Cytophotometry and to their possible future additional role in the diagnostics of the GCT and in the prediction of their biological behaviour. The female patient with only one lower limb (the other already amputated) now goes about smilingly selling her wares. The 198-amino-acid in-frame insertion in the gyrA gene of Mycobacterium xenopi is the smallest known naturally occurring active protein splicing element (intein).

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This study confirms that there is no standard for application of a girth and saddle in the Thoroughbred racing industry and the range of tensions applied was large. The presence of splenic vein thrombosis is sometimes very difficult to diagnose. Genome-wide gene expression studies and in silico analyses were carried out to predict miRNA regulation and investigate the functional significance and clinical utility of the novel oncogenic pathways regulated by these miRNAs in prostate cancer (PCa). Hck, a member of the Src-family of protein tyrosine kinases, is expressed primarily in hematopoietic cells of the myeloid and B-lymphocyte lineages. Garlic Organosulfur Compounds Reduce Inflammation and Oxidative Stress during Dengue Virus Infection. A study of water quality parameters (temperature, conductivity, total dissolved solid, dissolved oxygen, pH and water hardness) in Ampang Hilir Lake was conducted in January, April, July and October 2010. We report findings from a pilot data collection study within a programme of quality assurance, improvement and development across all five homeopathic hospitals in the UK National Health Service (NHS). The effect of level of intake on calcium and phosphorus metabolism in college women.

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To investigate current preferences and opinions on the diagnosis, treatment and rehabilitation of patients with anterior cruciate ligament (ACL) injury in Croatia. It is possible that plasma from subjects with an anticardiolipin antibody (ACA) without an LA could also affect the INR. DPP IV has been implicated in hepatocyte-extracellular matrix interactions, fibroblast activation and proliferation and in T-cell activation. This article summarizes key findings and discussions from the meeting on modelling needs related to HSV burden, costs, and vaccine impact, essential data needs to carry out those models, and important model components and parameters. The prevalence of risk factors in those who enter the prevention programme is high, which places great demands for treatment and follow up.

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The presence of PEO-PPO on the surface of the nanoparticles and its interaction with the CS was identified by X-ray photoelectron spectroscopy (XPS). Environmental regulation of virulence factors in Bordetella species. capsulatus RNAP/sigma70) was purified and characterized using two classical sigma70 type promoters, the bacteriophage T7A1 and the RNA I promoters. Determination of brazilein in rat plasma after intravenous administration by HPLC. Treatment and diagnostic measures should be taken in CRD patients to reduce the severity of periprocedural complications. Nociceptin/orphanin FQ (NC), the endogenous ligand of the opioid receptor-like1 (ORL1) receptor, has been reported to stimulate feeding in rats. Monitoring mangrove forests after aquaculture abandonment using time series of very high spatial resolution satellite images: A case study from the Perancak estuary, Bali, Indonesia. A group of 8 pediatric cardiologists formulated candidate QMs in the areas of history, physical examination, and testing. Although the use of extended criteria donors has shown great potential, it remains unregulated. With the scanning electron microscope we have examined normal cochlear sensory epithelium of the guinea pig and cat and that damaged by noise.

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These Jidoka rules can support executive FBs in performing different Jidoka functions. Twenty-four consecutive patients underwent heavily T2-weighted (hT2W) MR cisternography (MRC), hT2W 3-dimensional (3D) fluid-attenuated inversion recovery (FLAIR) with inversion time of 2250 ms (positive perilymph image, PPI), and hT2W-3D-IR with inversion time of 2050 ms (positive endolymph image, PEI) 4 hours after intravenous administration of single-dose gadolinium-based contrast material (IV-SD-GBCM). The acoustic environment of the bottlenose dolphin often consists of noise where energy across frequency regions is coherently modulated in time (e.g., ambient noise from snapping shrimp). A retrospective study was made of 16 children with 21-hydroxylase-deficient congenital adrenal hyperplasia of the salt-losing variety, who were treated with fludrocortisone and prednisone and were in good health during the period under review. The median age at the time of diagnosis was 45 years with the most common presenting symptom being hemoptysis (7 of 15 patients). Redox-dependent conformational changes are common structural features of cytochrome c from various species. Temporal and spatial control of the adenovirus proteinase by both a peptide and the viral DNA. Our data provide new information on the prevalence of mycobacterial infection among wild boars in Northern Sardinia and suggest that a more effective program should be developed to monitor mycobacterial infections in the wild animal population. Though her serum-free T3 was 17.8 pmol/L and free T4 was 60.2 pmol/L, TSH was as high as 10.7 mU/L.

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Influence of hepatic load from far-off dry period to early postpartum period on the first postpartum ovulation and accompanying subsequent fertility in dairy cows. Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy. A unified energy functional for a joint segmentation and registration is proposed based on the assumption that the statistical properties of dynamic intensity curves within a region of interest are homogeneous. Fourteen patients with an average age of 34.1 years at operation (range, 12-65) with post-traumatic bony defects of the tibia were selected for reconstruction with vascularised fibular graft combined with Ilizarov external fixation. Design of UWB monopole antenna with dual notched bands using one modified electromagnetic-bandgap structure. Coexistent multiple myeloma or increased bone marrow plasma cells define equally high-risk populations in patients with immunoglobulin light chain amyloidosis. Chronic granuloma following wound contamination by beryllium silicate. In this patient with sickle cell disease, although clinical examination was normal and FA did not show any capillary dropout, the SD-OCT showed inner retinal thinning temporal to the fovea. Seven of these families share a splice-site mutation in exon 1 of endoglin. q8h, decreased the toxicity and allowed for protracted administration of the combination.

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The impact of copper-catalyzed cross-coupling reactions in natural product synthesis will be overviewed in this article with an emphasis on the evolution of strategies due to copper catalysis, mostly by comparison with alternative tactics and their relative efficiencies. Single-fulcrum laparoscopic cholecystectomy in uncomplicated gallbladder diseases: a retrospective comparative analysis with conventional laparoscopic cholecystectomy. Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys. Plus-strand strong-stop DNA, which is found base-paired to near full-length minus-strand DNA in infected cells, is believed to be synthesized before the second template switch. Differences in age trends of infection were detected among settings. Reconstruction of an extraordinary extinct primate from Madagascar.

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In total, 78,400 self-administered anonymous questionnaires were distributed to college students in seven cities in China to determine the age at which Chinese college students first engage in sexual activity, and the association between AFSI and knowledge, attitudes and practices (KAP) regarding reproductive health and unplanned pregnancy. A series of aliphatic side-chain analogues of pseudomycin was synthesized and evaluated during the course of our side-chain SAR effort. Express photolithographic DNA microarray synthesis with optimized chemistry and high-efficiency photolabile groups. Catheter ablation of atrial fibrillation with box isolation of fibrotic areas: Lessons on fibrosis distribution and extent, clinical characteristics, and their impact on long-term outcome. In conclusion, clinical application of sairei-to could be an effective measure to prevent the occurrence of OME and also the recurrence of the disease, especially OME-prone individuals.

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In the last decade, event-related potential and functional magnetic resonance imaging studies were very useful in temporal and spatial localization of brain processes involved in the recognition of emotional facial expressions. Time-compressed spoken word primes crossmodally enhance processing of semantically congruent visual targets. To examine the impact of inflammation, insulin-like growth factor (IGF-1) and its regulating binding protein (IGFBP-1) on lean body mass (LBM) in patients with rheumatoid arthritis (RA). The numbers of both of M1 and M2 macrophages in the tongues of mice treated with 4-nitroquinoline-1-oxide (4NQO) were significantly lower compared with those of normal tongues. As predicted, the slope of the semilogarithmic plots were related to the disintegration decay constant for tablet erosion in the basket. The retinal photoreceptors of the tiger salamander (Ambystoma tigrinum) have been studied by light and electron microscopy in both light- and dark-adaptation. Further study on the regulation of miRNAs by metformin could result in novel therapeutic strategies for recurrent or drug-esistant cancer, and as part of combinatorial approaches with conventional anticancer therapies. Several lines of evidence have demonstrated the potential biomedical applications of fumaric acid (FA) and its ester derivatives against many human disease conditions. In two-way MLRs ONX-0914 inhibited cell proliferation more than CEP-18770. Moreover, nursing courses need to ensure that socialisation issues are addressed to assist in the eradication of oppressive practices.

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Venom-induced inactivation appeared to require few, if any, serum cofactors, because, with the possible exception of C2, functionally pure components, as well as those in sera, were readily inactivated. Root-bearing axes preserved in growth position exhibit evidence of positive gravitropism, whereas the lateral roots extend horizontally. The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons. In particular, the Collaboratorium represents a novel distribution method that could increase the reproducibility and reusability of results from similar large, multi-omic studies. Hippo signaling serves to limit organ size and suppress malignancies, and has been implicated in tissue regeneration following injury. The most common cause of cognitive dysfunction in children is Down syndrome (DS). Genistein supplementation improves insulin resistance and inflammatory state in non-alcoholic fatty liver patients: A randomized, controlled trial. NDMA was the most abundant N-nitrosamine, while NDPhA was firstly identified in human. Factors affecting the clearance and biodistribution of polymeric nanoparticles. Exogenous Application of Citric Acid Ameliorates the Adverse Effect of Heat Stress in Tall Fescue (Lolium arundinaceum).

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The easy-handling Langlois reagent, as well as N-halophthalimide and N-trifluoromethylthiosaccharin, is used in this method. To investigate the ultrasonographic (US) features of anaplastic thyroid cancer (ATC) and the diagnostic performance of US-guided fine needle aspiration theolair biopsy (FNAB) therein. The available evidence indicates that enteroclysis is superior to the follow-through for detecting and demonstrating morphological abnormalities in the intestine. Total treatment could thus involve endodontic, orthodontic, periodontic, and restorative procedures. This secondary analysis used data from the HIV Cost and Services Utilization Study. CBM may offer novel approaches for high speed dynamic phase corrections in optical systems and find applications in sensing and navigation. Primary central nervous system lymphoma presenting with multiple myeloma-like clinical picture. This study aimed to explore the concordance between definitions of sarcopenia and frailty in a clinically relevant population of geriatric outpatients.

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Dermatofibrosarcoma protuberans presenting as a subcutaneous mass: a clinicopathological study of 15 cases with exclusive or near-exclusive subcutaneous involvement. The LOM was stained with lissamine green (Odyssey Medical, TN) for evaluation. Hence, total human clearance and relative contributions of elimination pathways were successfully predicted by the presented method using solely hepatocyte and microsome in vitro data. Increase in migraine diagnoses and guideline-concordant treatment in veterans, 2004-2012. In addition, to elucidate each intracellular mechanisms, we examined the effects of an inhibitor of cAMP-dependent protein kinase, an inhibitor of particulate guanylate cyclase, and an inhibitor of soluble guanylate cyclase on the adrenomedullin- or guanylin-induced relaxation of the caecal circular smooth muscle cells. GVHR can also be acquired in utero by maternal cells crossing the placenta, but the fetal target organs are unknown. Circulating cytokines may promote myocardial dysfunction (stunning) after ischemia. Pulmonary Infections in the Elderly Lead to Impaired Neutrophil Targeting, Which Is Improved by Simvastatin.

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The purpose of this study was to investigate the incidence of esophagojejunal anastomotic leakage (EJAL) after total gastrectomy. The clinical significance of the expression of costimulatory molecule PD-L1 in nasopharyngeal carcinoma. Hierarchical self-assembly of nematic colloidal superstructures. However within a specialist centre the accuracy of successful prenatal detection can be significantly improved. The implication of the relaxation-induced frequency shift of the lines (dynamic frequency shift) for the accurate measurement of residual dipolar couplings in field-oriented systems has been discussed. Development of a disaggregation-induced emission probe for the detection of RecA inteins from Mycobacterium tuberculosis.

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We compared several activation markers and parameters of biological activity of DNA- and mRNA-transfected DCs in vitro and in vivo. After curettage and bone grafting, giant cell tumor of bone may transform to malignancies within a few years or even decades after surgery. Cells from human melanoma lines (A-07, D-12, R-18, and U-25) transplanted to BALB/c nu/nu mice were used as tumor models. After intracerebral inoculation of mice with a 10 per cent suspension (approximately 2000 LD(50)) of the Lansing strain of poliomyelitis virus, the neurontin scheduled drug infectivity titer in the brain decreased for approximately 6 hours. A phase variance mask is then employed to segment meaningful Doppler flow signals from noisy phase background. This rare presentation warrants a thorough investigation to identify the source of infection. Anatomic and functional hypoplastic left heart syndrome and its surgical Norwood and Fontan treatment. Long-term regular dental attendance and periodontal disease in the 1998 adult dental health survey.

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Nutritional status at admission of children with cancer in Malawi. A bipartite C-terminal domain of TAg binds to p53 and thereby disrupts the ability of p53 to act as a sequence-specific transcription factor. Congenital pediatric kidney disease included polycystic kidney disease, hypoplasia, dysplasia, dysgenesis, agenesis and familial nephropathy. Role of bacterial cytotoxins penicillin allergy and omnicef in hemolytic uremic syndrome and thrombotic thrombocytopenic purpura. Arterial tonometry is a non-invasive technique for continuous registration of arterial pressure waveforms. Status epilepticus, particularly non-convulsive status epilepticus (NCSE), is a frequent complication in patients with altered renal function receiving treatment with intravenous cefepime. In addition, two specific features of plant frataxins were evidenced: their ability to form dimers and their tendency to undergo conformational change under oxygen exposure. However, LS should be diagnosed and performed by a surgeon skilled in proctologic surgery. Acute liver insufficiency is a rare complication of anorexia nervosa. The presented results show that APT imaging is sensitive to HIFU-induced changes in tumor tissue and may thus serve as a new biomarker for monitoring the response of tumor tissue to HIFU treatment.

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Account for Clinical Heterogeneity in Assessment of Catheter-based Renal Denervation among Resistant Hypertension Patients: Subgroup Meta-analysis. This study showed that the action of nicardipine is modified by different inhalational anaesthetic agents. L-arginine reduces liver and biliary tract damage after liver transplantation from non-heart-beating donor pigs. Collectively, the results show how Co(salophen) and p-hydroquinone operate synergistically to mediate O2 reduction and generate the reactive p-benzoquinone co-catalyst. In FTD, metabolic and morphologic changes occur in the bilateral frontal lobe and temporal lobe with a limited asymmetry whereas there was considerable discordance in the AD group. Melanosomes reduced the proliferation of SV-HEKs in a dose-dependent manner, but did not induce differentiation. When an ovarian tumour is found in a young woman a frozen-section examination must be carried out to make the diagnosis and perhaps avoid oophorectomy, particularly when untwisting a torsion can lead to resorption of the edema. An adjustment to the 1997 estimate for new prostate cancer cases.

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The most frequently reported own capability was self-motivation. A retrospective quasi-experimental study of a transitional housing program for patients with severe and persistent mental illness. One to 6 days before surgery, the patients underwent an endoscopic transpapillary pancreatic stent (7 Fr., 3 cm) placement. The marked correlation between ATO-induced mitotic arrest and apoptosis indicates that the induction of apoptosis by ATO was highly dependent on the functional activation of the spindle checkpoint in cancer cells lacking normal p53 function. Interrogation of human cancer gene expression data revealed that high TNC expression correlates with worse prognosis for lung adenocarcinoma, and that a three-gene expression signature comprising TNC, S100A10, and S100A11 is a robust predictor of patient survival independent of age, sex, smoking history, and mutational load. Results of this study demonstrated that ESWT is effective in promoting spinal fusion in rabbits. Altered composition of high density lipoproteins in women with the polycystic ovary syndrome. Moreover, we discuss studies concerning anticancer properties of presented synthetic antioxidants and their application in several angiogenesis-related diseases. Players with present or past DOM shoulder pain demonstrated greater laxity in their DOM dorsal capsule, tightening of their DOM inferior capsule, and lower SS compared with those without shoulder pain.

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