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Alpam (Alprazolam)

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Alpam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alltop, Alpanol, Alpra, Alpraquil, Alprasert, Alprocontin, Alpronit, Alprozam, Alzex, Alzoax, Alzopax, Ansilumirm, Anxilam, Copax, Depflu, Destres, Dipra, Elzopam, Endolam, Exprex, Finezol, Flunix, Hipose, Isorest, Morecalm, Nexlpra, Normatine, Notence, Plaxid, Plxna, Prozolam, Pyrex, Restam, Rivcam, Rozin, Setex, Somnarest, Sozox, Tancalm, Tenschem, Visram, Xycalm, Zallpam, Zolorest, Zomark, Zotam

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Temovate, Naprosyn, Levaquin, Zyprexa, Uroxatral, Zetia, Tofranil, Obeta, Propanz, Wymox, Excita, Stabilanol, Relfen, Minegyl,

Also known as: Alprazolam


Alpam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alpam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alpam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alpam or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alpam. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpam XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alpam for medical reasons, the best way to avoid a Alpam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alpam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alpam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alpam is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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Subjective ratings of credibility following brief exposure to desensitization and pseudotherapy. Upregulation of STS expression plays an important role in tumor progression of human breast cancer and is considered to be responsible for estrogen production in tumor and surrounding tissues. Tracheal resection associated with slide tracheoplasty for long-segment congenital tracheal stenosis involving the carina. The objective of this study was to determine in ambulatory pediatric setting impact of IRDT on the management of febrile children during an epidemic, especially on other diagnostic testing performed, antibiotic and antiviral treatments. In what is the function of albendazole tablet the mean time, many if not most renal transplant recipients should be treated with HMG-CoA reductase inhibitors starting early posttransplant to prevent cardiovascular disease complications. An electronic literature search was performed of the Medline, Embase and Cochrane library databases along with the PubMed US national library from January 1950 to December 2012 to identify relevant articles. The successful management of congenital laryngeal web with endoscopic lysis and topical mitomycin-C. Richner-Hanhart syndrome (tyrosinaemia-II) (report of four cases without ocular involvement). Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-kappaB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility.

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Efficacy of adjuvant immunochemotherapy with polysaccharide K for patients with curative resections of gastric cancer. Truncated initiation factor eIF4G lacking an eIF4E binding site can support capped mRNA translation. Bemiparin prophylaxis, started 6 h after surgery and given for 5-6 weeks after total hip or knee replacement, was associated with low rates of VTE, major bleeding and other adverse events in normal clinical practice. Design and performance of a universal sheathless capillary electrophoresis to mass spectrometry interface using a periactin max dose split-flow technique. A country-wide survey of HAV antibody positivity and selected risk factors was conducted among 18-69 year olds identified by random digit dialing, in samples proportional to regional populations. In addition, batch-wise reinterpretation of previous typing data can be performed either using the NCBI web site or by locally using downloaded allele-reactivity lists. Further, how she has gone from a state of hopelessness in the early days to a reconstructed identity, associated with a new insight during the 2 years after the accident through a complex and dynamic process of change. Major advances have been made in the understanding of the pathophysiology of this disease, and causative genetic defects have been recently identified for two conditions-polysaccharide storage myopathy of quarter horses, paints, warm bloods, and draft breeds. We demonstrated the usefulness of diffusion-weighted imaging with a high b-factor to detect renal cancer presenting with peritoneal metastasis in a patient with ACDK.

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Letter: Uptake of 35S-heparin by lymphocytes from cystic-fibrosis patients. Effects on angiotensin-converting enzyme inhibition on renal hemodynamics in renal artery stenosis. Additionally, the accumulation profiles of the intermediate metabolites of esculeoside A biosynthesis in ripening mutant fruits suggest that a glycosylation step in the putative pathway from alpha-tomatine to esculeoside A depends on ethylene. Unintentional childhood injuries in the United States: key findings from the CDC childhood injury report. The predominant lineage infecting turkeys is genetically related to the American TAstV2, but genetic variability within this lineage was demonstrated. Monosodium urate monohydrate crystals drive the disease and identification of these crystals is required for certain diagnosis. Thus, the results will be both a help for the adolescents within the study and for others in the future given that the trial will lead to a positive adalat 5 mg kapseln finding. However, even if Principal Component Analysis was used, the reflection of horny was not able to be removed completely.

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