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Alpostin (Alprostadil)

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Alpostin is a medication used in the management and treatment of erectile dysfunction in males and for temporary patency of ductus arteriosus in newborns with congenital heart diseases before surgical intervention. It is in the prostaglandin analog class of medications.

Other names for this medication:
Alpostin, Caverject, Edex, Muse, Prostin, Vitaros

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Also known as: Alprostadil


This medication is used to treat male sexual function problems (erectile dysfunction). It works by helping the blood flow into the penis to achieve and maintain an erection. This medication is not for use in women or children.


A healthcare provider will give your first dose and teach you how to properly use the medication by yourself.

Follow all directions on your prescription label and read all medication guides. Use the medicine exactly as directed.

Alpostin is used only when needed. An erection should occur within 5 to 20 minutes and last up to 60 minutes.

Alpostin injection is injected into the side of the penis.

Alprostatil transurethral pellet is a very small suppository to be inserted into the opening of the penis (the urethra).

Do not use more than 2 pellets in one day. Do not use more than 3 injections per week. Wait at least 24 hours between each injection.

Ask your doctor or pharmacist if you don't understand how to use the injection.

Prepare an injection only when you are ready to give it. Call your pharmacist if the medicine looks cloudy, has changed colors, or has particles in it.

Do not reuse a needle or syringe. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. Keep out of the reach of children and pets.

Call your doctor if a needle breaks while you are injecting Alpostin. If you can grasp the broken end, remove the needle right away.

Your doctor should check you every 3 months to be sure Alpostin is not causing harmful effects on your penis.

Storing Alpostin:

Keep pellets in their original foil pouch in the refrigerator. You may store a pouch at cool room temperature for up to 14 days. Protect from freezing or extreme heat. Do not store in a closed automobile or in luggage while traveling. Store Alpostin injection vials at cool room temperature. The 40-microgram strength should be used within 3 months or before the expiration date on the label. After mixing a Caverject injection, keep it at room temperature and use within 24 hours.

Detailed Alpostin dosage information


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately. The overdose of the medication may be followed by feeling light-headed, fainting, having a painful or prolonged erection lasting 4 hours or longer.


Side effects

The most common side effects associated with Alpostin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to Alpostin or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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