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Alprasan (Alprazolam)

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Alprasan is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprasan, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprasan is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alcicalm, Aldep, Alfix, Alparazole, Alprasert, Alprotame, Alprowon, Alrif, Alzam, Alzonex, Anilam, Anxicalm, Anxofit, Anxorel, Censir, Depflu, Elflu, Enxolam, Eurolam, Himzolam, Imprax, Manzolam, Mebaspa, Mebrin, Mediprex, Morecalm, Notens, Prolam, Pyrex, Samprex, Selamb, Tenil, Tenolam, Tensfree, Tensyn, Zepro, Zolax, Zoldac, Zolran, Zolyde

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Also known as: Alprazolam


Alprasan XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprasan XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprasan XR may also be used for other purposes not listed in this medication guide.


Take Alprasan exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use Alprasan in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.

Alprasan may be habit-forming. Never share Alprasan with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Do not crush, chew, or break a Alprasan extended-release tablet. Swallow the tablet whole. Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms. Do not stop using Alprasan suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.


If you have been prescribed Alprasan for medical reasons, the best way to avoid a Alprasan overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprasan consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprasan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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In addition, it was found that a high percentage of T lymphocytes from both peripheral blood and synovial tissue of rheumatoid patients bound anti-HLA-DR antibodies. The diversity of the results shows that various types of experimental infections should be used when testing an antibiotic. Antiserum to BAdV-6 did not neutralize the deer adenovirus but antiserum to BAdV-7 and GAdV-1 neutralized the deer adenovirus. Cooperation among workers and their seeming altruism result from strict policing by nestmates. We reviewed the usefulness of platelet scintigraphy, in which autologous platelets labeled with indium-111-oxine reveal thrombotic activity, for evaluating deep vein thrombosis (DVT). Uncertainty in MR tracer kinetic parameters and water exchange rates estimated from T1-weighted dynamic contrast enhanced MRI. Subclinical diabetic neuropathy: a common complication in Saudi diabetics.

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Continuing research and development are resulting in the production of new technologies and products, giving clinicians even more choices in designing and fabricating metal-ceramic restorations. A transversal study on antibodies against selected pathogens in dromedary camels in the Canary Islands, Spain. Unlike previous multispectral I-DT methods, the proposed method does not require a nondispersive assumption. Only licensed origins can initiate replication, and the cytoplasm interacts with the nucleus to inhibit new licensing during S phase. All these patients had a baseline BMD measurement by DEXA scans in the region of the lumbar vertebrae before treatment and the T-score was computed. Although cell movement was induced up to seven segments proximal from the level of amputation, cells located within two segments from the wound provided the main contribution to the blastema. We assessed park use in Recife, Brazil, and differences in physical activity and occupation rates in public parks with and without the Academia da Cidade Program (ACP), which provides cost-free, supervised physical activity classes. We present evidence that down-regulation of Cdk1 activates Wee1 and Myt1 kinases and inhibits Cdc25 phosphatase during the M to G1 transition. The tumor was illuminated with a 632.8-nm diffuse beam from a helium-neon laser.

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A 45-year-old man presented with gradual dyspnea, abdominal distension, and pedal edema of six-month history. Children with a low MPH dose before medication switch had a higher chance of being in the patient cluster with a strong treatment response after switching medication. Here, we describe a machine-learning approach to the prediction of levels of oxidative stress in human subjects. Staining of F-actin with nitrobenzoxadiazole (NBD)-phallacidin demonstrated that LatB significantly impaired F-actin stress fiber formation. Although specialists have traditionally rendered this therapeutic procedure, in simple cases there is seldom need for extensive surgical procedures and therefore there is a clear need to introduce these studies in modern dental curricula. There was no significant difference in TVC among the groups on Day 2. The parameters evaluated included the following: fecal fat excretion, coefficient of fat absorption, daily caloric intake, percent of diet as fats, proteins and carbohydrates, increase in height and weight, frequency and consistency of stools, palatability of the preparation, and patient compliance.

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Tests concerning the strength of fixation with different types of implants have been carried out on prepared models. Using Medicaid prescription data for amoxicillin/clavulanate, metformin, and omeprazole, we calculated the savings that could have been realized if generic drugs had been available and fully substituted at their lowest cost when IP protection first expired (an average delay of twenty-six months). We set out to establish a more accurate prevalence estimate for CD using a novel serogenetic approach. SELDI-TOF analysis with CM10 or IMAC30 (but not Q10) protein chips detected a protein peak at m/z approximately 8570 released by both C57BL6 and hybrid embryos. Study reveals progressive decreased activity of the enzyme in all the animal groups with increasing the duration of the dose except two days treated animals. Major developmental events in early Xenopus embryogenesis coincide with changes in the length and composition of the cell cycle.

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Prognostic informativity some indexes of immune response in severe shockogenic combined thoracoabdominal trauma was studied. These include better recognition of critically ill patients at risk of cardiac arrest, improved quality of cardiopulmonary resuscitation, defibrillation strategies, which minimize pre- and post-shock pauses and development of post-resuscitation care bundles. Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. Canalicular secretion of bile acids is stimulated by tauroursodesoxycholate (TUDC). Blockade of opioid receptors improved significantly glucose tolerance and glucose-induced insulin secretion in uremic patients and suppressed nearly completely glucagon secretion response during the second phase of a glucose tolerance test.

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Ultrastructural changes in the spermatogonia and spermatocytes of Poecilia reticulata during spermatogenesis. We demonstrated that SOD1 IC induced a Fcgamma receptor (FcgammaR)-dependent intracellular delivery of the antioxidant enzyme in IFN-gamma activated murine macrophages (the J774 AI cell line). Percutaneous antegrade ureteric stent removal using a rigid alligator forceps. In order to compare the catalytic properties of the two enzymes in the isolated and in the multi-enzymatic approach, two other single enzyme bioreactors based on trypsin and chymotrypsin were prepared following the same immobilization protocol. Ventricular assist devices are an important component in the arsenal of therapies to support the failing heart. Although no SNP-depeding formation of the DNA-protein complex was evident, future investigations could reveal differential molecular mechanisms of cellular regulation. An intermittent sinusoidal pattern resolved, in one fetus, with sonographic evidence of delayed but complete absorption of transfused red blood cells.

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Analysis of pesticides in water using silica gel column clean-up. We have designed and obtained the first in vivo validation of a neural probe with monolithically integrated electrodes and waveguide. The role of the medial frontal cortex in cognition continues to generate both interest and controversy. Open procedures in this series had a complication rate equal to or lower than published rates in endoscopic brow-lift series. Biochemical and mood responses predictive of stressful diving performance.

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It is possible to predict the development of postoperative hydrocephalus in patients with spina bifida by measuring cranial ventricular dimensions using preoperative ultrasound. Oral toxicity of the cyanobacterial toxin cylindrospermopsin in mice: long-term exposure to low doses. We derived explicit expressions for the basic reproduction number and the elimination threshold. SOAR and the polybasic STIM1 domains gate and regulate Orai channels. The degree of thigmomorphogenesis was either independent of light climate or stimulated by spectral shading. The relevance of well-analyzed drug-resistance mechanisms, e.g., intracellular/extracellular transport and induction of certain enzyme systems, is reviewed. A patient with familial amyloid polyneuropathy and congestive heart failure underwent myocardial imaging using technetium-99m pyrophosphate. The purpose of the present study was to detect bacterial strains and antibiotic susceptibility in chronic tonsillitis patients with IgA nephropathy (IgAN) and without nephritis, in order to provide evidence for clinical therapy and pathogenesis of IgAN. Effect of curcuma on radiation-induced apoptosis in human cancer cells. Mosquitoes of the mangrove forests of India: part 7--an overview.

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Control of the dominant and nondominant hand: exploitation and taming of nonmuscular forces. To study the difference at the protein expression level of the embryos of haploid and diploid in development, we extracted the total proteins of both the gynogenetic haploid and diploid embryos of goldfish in the same eye formation stage. This study investigated the removal of N-nitrosodimethylamine (NDMA) by an adsorption mechanism using commercially available activated carbons and surface-modified activated carbons. Awareness of the extent and nature of published research involving HIT interventions used in this way is currently lacking. To investigate the susceptibility, to a range of different biocides, of Pseudomonas aeruginosa strains variously deficient in N-acyl homoserine lactone systems, grown either as planktonic or biofilm populations. Predictable changes in blood biochemistry and coagulation occur following major hepatic resection and alterations from the expected path indicate a complicated course.

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On the ninth day all mice in groups B, C and D were orally inoculated by 1 x 10(6) oocysts amaryl 4 mg of C. All peptides were able to penetrate into monolayers made with negatively charged phospholipids, but only two interacted weakly with neutral lipids. The considered research areas are by no means disjointed, because they share common theoretical and methodological features. During the first hour of interaction with target cells the numerical density of the GA decreased and there was no increase during the rest of the observation period, whereas in the control lymphocytes the density of GA increased from the second to the third hour of interaction with target cells. Group I received postoperative intranasal steroid and group II received postoperative intranasal saline spray.

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Proceedings: Sensitivity of transmitter substances and synaptic formation in cultured neurons. We would recommend further studies with larger samples and possibly including placebo controls. Consequently, the development of more specific countermeasures is of high priority for the preparedness of many nations. Presbyterian Healthcare Services in Albuquerque has been building such a system since 1999, beginning by automating pharmacy operations to support bar-coded medication administration. The average Cd concentrations reached 36.9 and 141 mg kg(-1) in Solanum nigrum leaves and Lobelia chinensis shoots, respectively.

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Dental tissues contain regular microscopic structures believed to result from periodic variations in the secretion of matrix by enamel- and dentine-forming cells. We had identified some genes which could be the molecular marker during the carcinogenesis and the development of the NPC. l-glutamine (Gln) is an energy source for gastrointestinal (GI) epithelia and can stimulate glucagon-like peptide 1 (GLP-1) release from isolated enteroendocrine L-cells. Rapid changes in the healthcare sector and human resource shortages have had an impact on the stability of global work environments, making maintaining professionalism a challenge. The ethical framework for this approach has been accepted in rehabilitation literature, but this is the first demonstration that relevant patient populations agree with this approach.

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Laparoscopic excision of choledochal cyst and Roux-en-Y hepaticojejunostomy in symptomatic neonates. Antioxidant and neuroprotective effects of Scrophularia striata extract against oxidative stress-induced neurotoxicity. A cell-free assay for detecting HDL that is dysfunctional in preventing the formation of or inactivating oxidized phospholipids. High-dose versus standard-dose PPI in triple therapy for Helicobacter pylori eradication. It has been found that in the presence of a functionally active and endogenous or added rho factor, only a limited number of the viral genes (A, B, and D) are expressed effectively, whereas the expression of genes, F, G, and H, which encode capsid proteins, is strongly inhibited. In contrast, none of the cyclotides had high activity against S. Green fluorescent protein (GFP) and its many variants are probably the most widely used proteins in medical and biological research, having been extensively engineered to act as markers of gene expression and protein localization, indicators of protein-protein interactions and biosensors. trachomatis in an enzyme-linked immunosorbent assay, microimmunofluorescent test and complement fixation test.

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The natural radionuclide contents of limestone and gypsum samples used as building raw materials in Turkey were measured by means of gamma spectrometer system with HPGe detector. It is uncertain whether the hyperglycemia per se is a cause of adverse clinical outcomes or whether the incidence of adverse outcomes can pyridium 200 mg cost be reduced by treatment. Ginseng populations that were harvested responsibly (i.e., planting seeds from harvested individuals) had higher growth rates than those that were harvested irresponsibly. Phosphorylation within a specific domain of the phosphoprotein of vesicular stomatitis virus regulates transcription in vitro. To date, there is no strategy for the prevention of early neonatal sepsis due to ampicillin-resistant E.

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Changes in sodium concentration profiles accompanying transmembrane water flow permitted calculation of the activation energies: 14 kcal/mol for protein-free lipid bilayers and 4 kcal/mol for lipid bilayers containing AqpZ. Among the patients with a visible bare area, the position was measured, and when eccentrically located, an apparent bone loss or gain was calculated. Hyperphagic short stature and Prader--Willi syndrome: a comparison of behavioural phenotypes, genotypes and indices of stress. It is not known whether these newer devices have improved outcomes, and particularly in compensated workers. Affinity determination of ricinus communis agglutinin ligands identified from combinatorial O- and S-,N-glycopeptide libraries. and supplied with salicylate, Chlorella sorokiniana had the highest removal rate (19 mg l(-1) h(-1)), followed by the wild Bolivian strain (18 mg l(-1) h(-1)) and Chlorella vulgaris (14 mg l(-1) h(-1)). A logical elaboration of this idea leads to a dynamical neural architecture that oscillates between two fundamental network states, one driven by external input, and the other by recurrent synaptic drive in the absence of sensory input. This paper demonstrates how to build systematically a discrete model, which reflects provably the qualitative biological behaviour without any knowledge of kinetic parameters. We have further used this information and that collected from other sources to compare the response of these three mite species to pesticides. In this study, risperidone appeared superior to pimozide for tic suppression but was associated with greater weight gain.

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To compare the number and type of nevirapine (NVP) resistance mutations detected in Ugandan women with subtype A vs. Also ineffective were lesions of the granular components of the visual Wulst, which receive the ascending thalamofugal fibers. Using audio-recordings from breastfeeding workshops antenatal classes, the data were analysed using a qualitative, discursive methodology based in part on the premises outlined by Potter and Wetherell (1987) and Edwards and Potter (1992, 2001). By fitting the conductance changes in the molecular junction using a simple model for inelastic transport, it is possible to estimate the phonon damping rates in the molecule. Podporozniy Sayano-Shushenskaya hydroelectric power station in August 2009. For this reason, the current review focuses more on the histological outcomes regarding liver fibrosis in patients who have not attained viral response to therapy (non-responders) or who already have biopsy defined cirrhosis. Human creatine kinase: isolation and sequence analysis of cDNA clones for the B subunit, development of subunit specific probes and determination of gene copy number. The hypothesis of fetal origins of adult disease has during the last decades received interest as an explanation of chronic, e.g. WITHDRAWN: Transient unidirectional acoustic streaming in annular resonators. Immunohistochemical localization of IGF-I, IGF-II and MSTN proteins during development of triploid sea bass (Dicentrarchus labrax).

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The Aurora kinase complex, also called the chromosomal passenger complex (CPC), is essential for faithful chromosome segregation and completion of cell division. At all other test sites, a significant decrease in elasticity parameters (Ue, Ur, Ua/Uf, Ur/Uf) and an increase in viscoelasticity parameters (Uv, Uv/Ue) of the skin were observed. Local fibrinolysis was not performed in combination with the above procedure. To determine whether the ratio of hepatocyte growth factor (HGF) to transforming growth factor beta1 (TGFbeta1) in systemic lupus erythematosus (SLE) nephritis could be a prognostic factor for response to therapy with cyclophosphamide (CYC) and steroids at 6 months, and to examine whether the molecular ratio of HGF to TGFbeta1 correlates with the activity index (AI) and chronicity index (CI) and has predictive value for remission at the sixth month. All MARCH proteins located to subcellular membranes, and several MARCH proteins reduced surface levels of known substrates of the viral K3 family. Dynamics of gut mucosal and systemic Th1/Th2 cytokine responses in interferon-gamma and interleukin-12p40 knock out mice during primary and challenge Cryptosporidium parvum infection. Challenges faced include a dearth of skilled workforce, inadequate health systems infrastructure, and lack of political will. Use of continuous wave Doppler ultrasound velocimetry to assess the severity of coarctation of the aorta by measurement of aortic flow velocities. The effects of a GABA(A) agonist in the rostral ventral medulla on sleep and breathing in newborn piglets. Dendritic cells (DC) are instrumental in orchestrating an appropriately polarized Th cell response to pathogens.

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All five carcinomas showed hybridization with HPV-11, four strongly reactive, and one also weakly hybridized with HPV-16. Pretreatment with THP was made 10 min before cocaine or MAP injection. Synthesis of some novel 4-arylidene pyrazoles as potential antimicrobial agents. Religiosity was measured using the Value on Religion Scale (Jessor and Jessor, 1977), and problem alcohol use was measured using the Composite International Diagnostic Interview-Substance Abuse Module (Cottler et al., 1989). Stable aqueous what class of antibiotics is keflex solutions of Fe-SWCNTs or Gd-SWCNTs were made using the biocompatible amphiphilic polymer N-(carbonyl-methoxypolyethyleneglycol 2000)-1,2-distearoylsn-glycero-3- phosphoethanolamine (PEG-DSPE). These integration models could be further developed through a focus on the common need of primary care and public health to address the health implications of the ever-present risk of emerging infectious diseases in Canada. Import of proteins from the cytosol into mitochondria is a key step in organelle biogenesis.

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When oocytes within preovulatory follicles were preincubated in the presence of FK for 2-10 hr, they matured normally after additional incubation for 10-20 hr in plain culture medium. Failure to have protocols in place for delivery of enteral nutrition (EN) through the perioperative period should not lead to inappropriate use of parenteral nutrition (PN) as a default therapy, because in many circumstances, standard therapy with no specialized nutrition support may be associated with better outcome. Quantitative RT-PCR identified AKR1C3 as the predominant AKR1C isoform expressed in acute myeloid leukemia (AML). glucophage xr 500 generic Necrotizing cellulitis complicating varicella in two children given nonsteroidal anti-inflammatory drugs. The general form of the dendritic tree is radiant and poorly branching. Pathophysiologically important is the development of inflammatory hyperaemia in the area of trophic ulcers, which is prognostically favourable for their healing. Effect of Zhongfeng Naodeping Granule on hippocampal excitatory amino acid and neuron of stroke-prone spontaneously hypertensive rats with hemorrhagic apoplexy. The patient with sixth nerve palsy had 5 PD of residual esotropia. The transient increase in c-fos and wee1 kinase genes is likely to be responsible for preventing premature mitosis while the cells remain in the G(1)/S phase of the cell cycle.

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