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Alprasert (Alprazolam)

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Alprasert is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprasert, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprasert is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alpaz, Alpkair, Alprac, Alprasan, Alprasert, Alpron, Alproz, Alzex, Alzolam, Alzom, Aryalam, Balzam, Cardilax, Dizeral, Notens, Omelam, Pacyl, Propnix, Restyl, Rezolam, Stresnil, Tenlax, Trazopin, Welnorm, Xycalm, Zedel, Zeprax

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Nizoral, Avelox, Ticlid, Flagyl, Abhigra, Zebeta, Aygestin, Zyvox, Ilosone, Zantac, Norfen, Monit, Pentasa, Chloramphenicol, Abzole, Alpanol, Oxpine, Pregnol,

Also known as: Alprazolam


Alprasert (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

Alprasert is used to treat anxiety disorders and anxiety caused by depression.

Alprasert is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase Alprasert on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprasert dosage information

Side effects

The most common side effects associated with Alprasert are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alprasert if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alprasert is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alprasert while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alprasert is not approved for use by anyone younger than 18 years old.

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Prediction of protein structural classes by recurrence quantification analysis based on chaos game representation. Behavioral observations reflected on consultation requests from primary medical-surgical services: are they predictive of delirium diagnosis and outcomes?. After verifying the performance of this technique, we carried out measurements to determine the landscapes of streptavidin-biotin interactions. Taken together, these data suggest autocrine Notch signaling, enhanced in response to tissue- or inflammatory-derived signals, influences eosinophil activity and longevity, which may ultimately contribute to the development of tissue eosinophilia and exacerbation or remediation of eosinophil effector functions. Serum fibronectin is elevated during normobaric and hyperbaric oxygen exposure in rats. We generated a knockin mouse that carries a mutation orthologous to the TRIC coding mutation linked to DFNB49 hearing loss in humans. The theoretical foundation of the instrument was based on a hypothesised theory of cognitive moral development in professional ethics, which was integrated into a selection of scenarios experienced in practice by pharmacists in NSW, Australia. Patient safety is a management issue, in view of the fact that clinical risk management has become an important part of hospital management. Patterned monolayers of neutral and charged functionalized manganese arene complexes on a highly ordered pyrolytic graphite surface. The aim of this study was to evaluate the complication rate of diagnostic carotid angiography performed by interventional cardiologists and compare it to previously published data.

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The cutoff frequencies were markedly high, considerably higher than the average firing rates. Three-dimensional 3-T TOF MR imaging of the LSAs in patients with insuloopercular gliomas can help to maximize the extent of resection without neurological complications, preserve the LSAs during surgery, and assist in patient selection. Antibodies to Epstein-Barr virus (EBV) antigens in sera of American Burkitt lymphoma patients. Topological and organizational properties of the products of house-keeping and tissue-specific genes in protein-protein interaction networks. In interphase cells, BICD2 mainly localizes to the Golgi complex and has properties of a peripheral coat protein, yet it also co-localizes with dynactin at microtubule plus ends. Smoking-associated increments in mean plasma norepinephrine and epinephrine as well as in heart rate and arterial pressure were demonstrated. Delivery of medication in aerosol form to the pediatric population is an important therapeutic module. Radiological assessment and functional evaluation confirmed significant improvement.

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The microcirculation within the EOMs tends to be impaired during the progress of disease, and the MR imaging pattern gives a semiquantitative measurement of the microcirculatory impairment of the EOMs during the edematous phase of the disease. Acetylsalicylic acid (aspirin) and the naturally occurring phytochemical salicylic acid had no effect on CYP activity. The ontogenetic patterns of cAMP specific binding in the papillary cytosolic fraction were different: the early increase in cAMP binding was protracted in the cortisol-treated rats, and no peak appeared at the age of 25 days. Perceiver effects as projective tests: what your perceptions of others say about you. The case report describes a woman with recurrent disease in subsequent pregnancies during the later stages of pregnancy. the objective of present paper was to study the amplitude-integrated EEG (aEEG) in hypoxic ischemic (HI) animal models and to test the reliability of aEEG method when used to monitor cerebral injuries. The system consists of two color cameras and two additional b/w cameras used for segmentation in the near-IR spectrum. Now protein binding can be mapped in a truly genome-wide manner with extremely high resolution.

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Opioid enhancement of perforant path transmission: effect of an enkephalin analog on inhibition and facilitation in the dentate gyrus. Cell lysates were analyzed for steroidogenic acute regulatory (StAR) and cholesterol side-chain-cleavage (P450scc) enzyme protein levels. Activity of beta-glucuronidase and cathepsin-D were studied in brain, spinal cord and sciatic nerves of rats at 24 h or 10 days after daily i.p. The origin of the TTR deposited in the peripheral nervous system is unknown. Action potentials were elicited by injections or infusions of acetylcholine, 5-hydroxytryptamine, bradykinin, phenyldiguanide, adrenaline and various other compounds. Measuring cognition in a geriatric outpatient clinic: Rasch analysis of the Montreal Cognitive Assessment. Physiological and behavioural processes in early maternal deprivation. The performance of the method, with special emphasis on the analysis of data with non-normal distribution of random effects, was studied using Monte Carlo (MC) simulations. Interestingly, disease stabilization or objective response resulted in comparable overall survival. Only 15 studies, relating to six different interventions, met the review criteria and most of these studies were not designed specifically to assess the impact of partnership working on public health outcomes.

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High-resolution DNA-binding specificity analysis of yeast transcription factors. Although randomized controlled trials (RCTs) are the gold standard for assessing efficacy of a drug intervention, because they are conducted in a highly selected group of patients, they do not necessarily reflect normal customary or optimized patient care. Phonological neighbourhood spread facilitates lexical decisions. Cost analysis and sociomedical aspects of the conservative and surgical treatment of hip osteoarthritis. To target the cytotoxicity of effector cells to CEA-expressing tumor cells, we employed recombinant DNA techniques to fuse recombinant human interleukin-2 (rhIL-2) to a single chain variable fragment (scFv) antibody derived from F11-39. After combined precapillary vasodilatation and non-selective beta-adrenoceptor blockade, the increase in blood pressure during stimulation with noise was not prevented. One recent method is the enactment of cost containment measures based on clinical practice guidelines (CPGs) that provide financial or administrative sanctions.

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Effects of preparatory procedures on the venom from a rattlesnake (Crotalus molossus molossus), as determined by isoelectric focusing. The observations suggest that an antigenic spectrum within a single related group exists for BVDV strains, rather than distinct serotypes. Data demonstrated that in vitro screening of cuttings represents a valuable way of assessing the ability of different poplar clones to take up, tolerate and survive metal stress. Indeed, the incorporation of such compounds has become more prevalent and is a growing trend in transdermal drug delivery. Diketopiperazines produced by endophytic fungi found in association with two Asteraceae species. FDG PET uptake as a predictor of pain response in palliative radiation therapy in patients with bone metastasis.

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The results of a clinical experiment that was carried out on a cadaver support the theoretical model derived and the miniature, bone-attached, robotic concept. Endothelial overproduction of reactive oxygen species, such as superoxide anions produced by NAD(P)H oxidase, induces endothelial dysfunction. The seemingly better DOTS implementation and treatment outcomes by the PPM must be evaluated further through cost effectiveness and efficiency studies. Papaverine-induced pial artery vasodilation was unchanged by fluid percussion brain injury and phenylephrine. Through a simple change of variable, we transform the Michaelis-Menten-type ratio-dependent model to a better studied Gause-type predator-prey system. Management poses challenges to the anesthesiologist, particularly in pregnancy. Our findings provide the first computational evidence for a significant role of long-range regulatory interactions due to telomere looping. Gastroesophageal reflux disease (GERD) has a negative impact on health-related quality of life (HRQoL). There were no significant differences in the amounts of phospholipid phosphorous between gramicidin pretreated and untreated skin. Do US ambient air lead levels have a significant impact on childhood blood lead levels: results of a national study.

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Ten patients did not use corticosteroids and 13 patients received postoperatively 400 mg hydrocortisone intravenously for 4 to 5 days followed by 90 mg prednisone per os thereafter. One hundred consecutive long-term estrogen and testosterone hormone implant users were assessed as to their knowledge of recent studies regarding risks of long-term HRT and whether they wished to discontinue lamisil treat yeast infection hormones. Translational inhibition is the primary event for gene silencing. Intraclass correlation coefficients (ICC) were used to estimate reliability. Irrespective of their type, the mode of transmission may be autosomal dominant or recessive, or X-linked.

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The adrenals are common metastatic sites for lung cancers as well as a number of other primary cancers. Cell counting kit-8 and flow cytometry were used for analyzing apoptosis in cells in vitro. Nitrate tolerance as a possible cause of multidrug-resistant coronary artery spasm. The association between obesity and asthma is well known but there is few information that relates metabolic syndrome with asthma. Here we describe a previously unreported X-linked brain malformation syndrome caused by mutations of CASK. Patency was restored to the access circuit by placing a new stent through the struts of the folded one. Other models of care are developing in the setting of managed care health plans that employ CKD disease management programs, either developed internally or in partnership with renal disease management companies. River ecology is a vital field in limnological research, and several new theories and methods have been developed and used in the study of lotic systems. Self-harm induced somatic admission after discharge from psychiatric hospital - a prospective cohort study. Effects of isoflavones from red clover (Trifolium pratense) on skin changes induced by ovariectomy in rats.

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Insulin also increased the affinity of the VTG receptor for its ligand. Characterization, risk stratification and the hypertension control rate at hospital-based clinics: a survey of 25,336 hypertensives in Beijing, Shanghai and Guangzhou. To better understand the incidence of thromboembolic disease in postoperative spinal patients, and to establish a starting point for defining appropriate postoperative prophylaxis protocols. In a third operation, performed with sodium fluorescein dying, the fistula was closed. From 2003 to 2008 we examined the HPV, cytology, and diagnostic results from almost one million cervical cancer screenings done on women aged 30 and older who were members in Kaiser Permanente Northern zithromax 500mg pills California, a large health maintenance organization that introduced cotesting in 2003.

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Univariate and multivariate analyses were used to evaluate the impact of EGFR and c-erbB-2 on DFS and PRFS. We report the observation of a 63-year-old patient who had a coronary angiography via the right femoral artery after a myocardial infarction. Combination with other techniques to better assess the fetal state. The influence of his investigations on the researches of other scientists in the field of quantum biophysics was shown. For the literature components, Mimosa provides paper status tracking and scoring of papers for annotation through a freely available machine learning approach, which is based on word correlation. Here we describe a tris(phosphine)borane-supported iron complex that catalyses the reduction of N2 to NH3 under mild conditions, and in which more than 40 per cent of the proton and cost of amiloride reducing equivalents are delivered to N2.

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Generalized idiopathic benign acanthosis nigricans in childhood. A reproducible pattern of increased ISS and lower GCS characterized by high severity, lateral crashes in children was noted. Evaluation of neurological complications in pediatric liver transplant recipients: MRI versus CT. During the first 5 days after acute lung injury onset, limitations were significantly more common in medical ICUs than surgical ICUs. Immunohistochemistry, RT-PCR, and direct sequencing were performed. The present article review actual concepts and data related to the psychological problems secondary to cancer, its evolution and treatment. Detection of overreporting of psychopathology on the Personality Assessment Inventory: a meta-analytic review. An 80 mV voltage influence led to a para que es minocycline 100 mg significant decrease in the expression of surface molecules CD 3, 11a/18, 3/69, 3/95, 19/69 and 19/95, and 200 and 300 mV voltages significantly decreased the expression of surface molecules CD 3, 19, 11a/18, 3/95 and 19/95 and significantly increased CD 19/69 expression.

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This estimation is usually performed in the Fourier domain by either successive or simultaneous estimation of the amplitude and phase of the Fourier transform (FT) of the PSE This paper addresses the problem of recovering the FT-phase of the PSF, which is an important reconstruction problem by itself. MTT assay was used to determine the multidrug resistance (MDR) of hepG2/ADM and BEL-7402/5-FU cells. Long-term effectiveness and safety of triple versus dual antiplatelet therapy after percutaneous coronary intervention for unprotected left main coronary artery disease. The differential expression of COX-1 and COX-2 in these neoplasms suggests that COX-2 rather than COX-1 may play a role in adenoma formation and/or growth in cases of SAP and FAP in humans. Development of hand preference in the Colorado Adoption Project. This paper examines why this kinematic pattern maximizes jump height in humans, given the design of the human musculoskeletal system. Comparative efficacy of besifloxacin and other fluoroquinolones in a prophylaxis model of penicillin-resistant Streptococcus pneumoniae rabbit endophthalmitis. To further understand this interaction, we used Reinforcement Learning models to test several distinct processing hypotheses. in each case Haemonchus contortus was the only species of nematode involved. To identify the optical coherence tomography (OCT) findings in patients with age-related macular degeneration (ARMD) treated with photodynamic therapy (PDT).

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Therefore, a careful assessment of the thyroid gland is necessary for patients undergoing LDCT for lung cancer screening. On the stability of chymotrypsin inhibitor 2 in a 10 M urea solution. As such, the size of a hapten should be an important determinant of its pharmacokinetics in animals harboring antibodies that recognize the hapten. Negative regulation of wnt11 expression by Jnk signaling during zebrafish gastrulation. In 1996, a new method, termed the yeast three-hybrid system, dedicated to selection of RNA binding proteins using a hybrid RNA molecule as bait was described. Chlorate and nitrate reduction pathways are separately induced in the perchlorate-respiring bacterium Dechlorosoma sp. Patients were asked to complete a questionnaire on clinical and sociodemographic parameters, and osteoporosis risk factors. Residents performing phacoemulsification surgery achieved a low overall rate of major complications.

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The results indicate that extensive chromosome fusions underlie the sharp decrease in the diploid number in the stone curlew. Future research is required to document the characteristics of FTV and epidemiological evidence is required to link exposure with injury. Modified BSA and pulse oximetry during swallowing, whether alone or in combination, showed inadequate sensitivity, specificity, and predictive values for detection of aspiration compared with videofluoroscopy in stroke patients. Serum creatinine, urea, and protein level changes in hydatidiform mole. Detection of dengue cell-surface antigens by peroxidase-labeled antibodies and immune cytolysis. Erythropoietin has recently been found to have cytoprotective effects in the central nervous system (CNS) and retina. The strategy considered herein features an iodocyclofunctionalization/hydrogen-transfer reaction sequence for the elaboration of propionate motifs. C(fraction)/C(sed) ratios ranged from 0.45 to 5.9 (median 1.5) without consistent differences among congener groups or consistent correlations against the number of chlorine atoms. To compare the prevalence of low apolipoprotein A1 levels and elevated apolipoprotein B, plasma fibrinogen, lipoprotein(a), homocysteine, and C-reactive protein levels by estimated glomerular filtration rate (GFR). Hyperparathyroidism during pregnancy: dangerous association for the mother and her infant.

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