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Alprogard (Alprazolam)
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Alprogard

Alprogard is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprogard, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprogard is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Almac, Alpradol, Alprazan, Alzocum, Anxico, Anxitab, Anxorel, Cardilax, Ecsit, Exiten, Fludep, Golprax, Maxorest, Nexlpra, Prazil, Prosanti, Resta, Resto, Samrox, Sowel, Tancalm, Tenfree, Tensyl, Texidep, Tranisol, Zeftra, Zepro, Zolark, Zolipax, Zolran

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Micardis, Vermox, Urispas, Minipress, Nuvigil, Tenormin, Imovane, Progene, Tackodom, Lorday, Auxxil, Dezacor, Meneklin, Clindacyl, Etofree,

Also known as: Alprazolam

Description

Alprogard XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alprogard XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alprogard XR may also be used for other purposes not listed in this medication guide.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprogard XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alprogard XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprogard XR dosage information

Side effects

The most common side effects associated with Alprogard are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of alprazolam in the pediatric population. Safety and efficacy have not been established.

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For the South African context, the community/hospital indicators are a measure of the extent of resource redistribution from hospital to community services and changing patterns of service utilisation over time. By phenol-water extraction an aqueous-phase soluble cellular lipopolysaccharide was isolated from Haemophilus pleuro-pneumoniae serotype 1. Duration of breast feeding and bovine serum albumin antibody levels in type 1 diabetes: a case-control study. Histological examination of the arterial system originating from the aortic adventitia in experimental atherosclerosis. The isolation from spleen tissue of high molecular weight proteins which alter vascular permeability: investigation of their pharmacological properties. Development of competitive PCR for detection of Butyrivibrio fibrisolvens in the rumen. Suicidal ideation of psychiatrically hospitalized adolescents has one-year predictive validity for suicide attempts in girls only. Basing lifetime cost estimates on short-term data overestimated the costs for ICH and underestimated those for IS. Reflex effects from the afferent fibers of the vagus nerve on the blood flow in the skeletal muscle and coronary vessels and cardiac contactility.

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Long-term effectiveness of a quality improvement program for patients with type 2 diabetes in general practice. The specificity and selectively of the targets of the new biologic agents render them less toxic than the oral maintenance drugs and thus could possibly replace those drugs most frequently associated with long-term toxicity such as the corticosteroids and the calcineurin inhibitors. Thus, administration of EtOH might increase the risk for compulsive use of MDMA, an issue that warrants further study. It is widely acknowledged that health information on the Internet is of variable quality and therefore the search and appraisal skills of consumers are important for selecting and assessing this information. Putative quantitative trait loci associated with the probability of contracting infectious bovine keratoconjunctivitis. Primary: incidence of human preembryos with chromosomal abnormalities.

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Fas apoptosis inhibitory molecule contains a novel beta-sandwich in contact with a partially ordered domain. Acetaldehyde increased the phosphorylation of beta-catenin on Tyr-331, Tyr-333, Tyr-654 and Tyr-670. Issues related to the design and interpretation of clinical trials of salvage therapy for invasive mold infection. Recognition of human polymorphonuclear leukocyte receptors for leukotriene B4 by rabbit anti-idiotypic antibodies to a mouse monoclonal antileukotriene B4. The effects of the larger doses of 7-NI (150 and 200 mg/kg) were effectively prevented by the increase of NO and not the ineffective dose of L-arginine. Gastric lipomas were characterized from the clinical viewpoint by dyspeptic disturbances that were not systematized, as well as by bleeding while the ileal and the colic tumours were accompanied by repeated invagination. This step-growth process can be controlled to prepare dimers, oligomers, and polymer-like gold nanoparticle chains by varying the ratio of alkanedithiols to nanoparticles.

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A generalized impairment in calcium handling in vascular smooth muscle,including the calcium influx through the voltage-operated and receptor-operated channels and calcium release from intracellular calcium stores, is involved in vascular hyporeactivity during the late phase of sepsis. As the proteasome plays a crucial role in the control of the inflammatory process and immune cell survival, targeting the proteasome appears as a novel approach for the prevention and treatment of inflammatory autoimmune diseases. Consequently, the proposed solution is of great interest and appears to be very promising, not only because of the numerous potential applications of XRD in materials science, but also the possible expansion of the solution to several other characterization techniques. Echocardiography during both provocative tests showed that the interatrial septum flattened or became convex toward the left atrium. At a mean follow-up of 42 months (range, 12 to 64 months), the mean preoperative Knee Society and function scores had improved from 24 and 34 to 94 and 85, respectively, at follow-up. We plan a cohort study in the general population aged 50 years and over to determine the course and prognosis of hand, hip, knee and foot pain, and the impact of these syndromes on participation levels and health care use. Genes in the deleted region possibly related to the clinical symptoms of our patient include NOTCH3 (MIM600276), causative of the vascular neurodegenerative disorder CADASIL and CASP14 (MIM605848), playing a central role in apoptosis in the inner root sheeth of the hair follicle. A microbiological etiology can be established in practically all cases. By blocking NMDA can i take zyrtec with cold medicine excitation or GABA inhibition, an excess of zinc may alter the excitability of hippocampal circuits, which contribute to the development of seizures. Hidden rheumatoid factor in latex negative test sera of patients with rheumatoid arthritis.

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Then, the changes of body weight, spleen index of mice, the inhibition rates of tumor, and the increase of life span (ILS) were all tested. Proteasome inhibitors had a similar effect to cadmium on the cellular accumulation of ATF5. Pit formation by a wavelength-tunable free electron laser (FEL) irradiation on the gypsum pellet maximized at a wavelength of 3.0 microm, 2 mJ/shot, and pits were not detected in those irradiated at 2.6 or 3.8 microm compared with the maximum at 3.0 microm and diminished at 2.0 or 4.0 microm in the human tooth case. Pneumonia hospitalizations were substantial, especially for the youngest and oldest age groups. It clicks when it is rolled and it squeaks when it is squeezed: what 10-month-old infants learn about object function. 1,2-Bis(N-fluoro-p-toluenesulfonamido)ethane chloroform solvate. Left main coronary artery embolus: unusual presentation mometasone formoterol generic of papillary fibroelastoma of the aortic valve.

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