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Alzero (Montelukast)
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Alzero

Alzero is an inexpensive drug used to treat asthma. It is also used to treat allergies. It is slightly more popular than comparable drugs. It is available in generic and brand versions. Generic Alzero is covered by most Medicare and insurance plans.

Other names for this medication:
Allrite, Alvergy, Alvizy, Alzero, Ancer, Breathezy, Centiluk, Coekastle, Deriphyllin, Ferodr, Fexokast, Histakind, Imont, Jotair, Leezet, Lelet, Levodel, Levoler, Levotra, Lewlet, Luvle, Maast, Monhale, Montair, Montelast, Montelukast, Montemac, Montral, Nexofex, Odimont, Pulmokast, Reakst, Renea, Rivoce, Romlist, Sigcet, Symkast, Tastymont, Telekast, Trimontemac, Tykast, Ventair, Ventyl, Xyvent

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Also known as: Montelukast

Description

Alzero tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.

Dosage

Usual Adult Dose of Alzero for Allergic Rhinitis:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose of Alzero for Asthma -- Maintenance:

-10 mg orally once a day Comments: -For asthma, efficacy has been demonstrated when this drug was administered in the EVENING without regard to time of food ingestion. -For allergic rhinitis, efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -Patients with both asthma and allergic rhinitis should take only one dose daily in the evening. Uses: -Prophylaxis and chronic treatment of asthma -Relief of symptoms of seasonal allergic rhinitis and perennial allergic rhinitis

Usual Adult Dose for Bronchospasm Prophylaxis:

-10 mg orally once a day at least 2 hours before exercise Comments: -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB)

Usual Pediatric Dose of Alzero for Asthma -- Maintenance:

Less than 12 months: Not approved. 12 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet or one sachet oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Doses should be taken in the evening. -Efficacy has been demonstrated for asthma when this drug was administered in the evening without regard to time of food ingestion. Use: Prophylaxis and chronic treatment of asthma in pediatric patients 12 months of age and older

Usual Pediatric Dose of Alzero for Allergic Rhinitis:

Seasonal Allergic Rhinitis: Less than 2 years: Not approved. 2 to 5 years: -4 mg chewable tablet or one sachet of 4 mg oral granules once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Perennial Allergic Rhinitis: Less than 6 months: Not approved. 6 to 23 months: -One sachet of 4 mg oral granules once a day 2 to 5 years: -4 mg chewable tablet orally once a day 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Efficacy has been demonstrated for asthma when this drug was administered in the MORNING or EVENING without regard to time of food ingestion. -The time of administration may be individualized to suit patient needs. Uses: -Relief of symptoms of seasonal allergic rhinitis in patients 2 years of age and older -Relief of symptoms of perennial allergic rhinitis in patients 6 months of age and older

Usual Pediatric Dose for Bronchospasm Prophylaxis:

Less than 6 years: Not approved. 6 to 14 years: -5 mg chewable tablet orally once a day 15 years or older: -10 mg tablet orally once a day Comments: -Dose should be taken at least 2 hours before exercise. -An additional dose should not be taken within 24 hours of a previous dose. -Patients already taking this drug daily for another indication (including chronic asthma) should not take an additional dose to prevent EIB. -A rescue short-acting beta-agonist should be available at all times. -Daily administration for the chronic treatment of asthma has not been established to prevent acute episodes of EIB. Use: Prevention of exercise-induced bronchoconstriction (EIB) in patients 6 years of age and older

Detailed Alzero dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Alzero are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Alzero if you are allergic to its components or to aspirin. Do not take Alzero if you use Alzero while you are pregnant or have nurseling. You should not use Alzero for exercise-induced bronchoconstriction if you already take Alzero to prevent symptoms of allergy or asthma. Try to be careful using Alzero if you take phenobarbital (such as Solfoton, Luminal), rifampin (such as Rifamate, Rifadin, Rimactane, Rifater). It can be dangerous to use Alzero if you suffer from or have a history of phenylketonuria, liver disease. Avoid any activities such as driving or operating machinery while taking Alzero. It can be dangerous to stop Alzero taking suddenly.

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In this sense it represents an upper limit when compared with in situ data (assuming the calibration constant is adequately chosen). This method improves the estimates of missing values by exploiting the cluster information such as cluster centroids and all available non-missing values in each iteration. Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older women. The data are provided about high efficacy of heparin therapy with low doses in combination with fresh-frozen plasma transfusions for thrombohemorrhagic complications in this patient group. Patients with asymptomatic bacteriuria may be treated with catheter removal only, and do not necessarily require antibiotic therapy.

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The enhanced cell division and expansion in the silique mesocarp layer, and increased lateral vascular bundle development imply FWF has roles also in modulating silique growth post-fertilization. Action selection processes such as those that underlie decisions about which hand to use for upcoming actions are fundamental to adaptive motor behavior. Overexpression of either Trisk 95 or Trisk 51 alters the muscle fiber morphology, while leaving unchanged the expression of the ryanodine receptor, the dihydropyridine receptor, and calsequestrin. Kinetics of alveolar macrophagic reactions was quantitatively studied at the endoalveolar and parietoalveolar levels after challenge by a single intratracheal administration of several agents, such as mineral dusts, antigenic particles, hormones and drugs. Cerium vanadate nanorod arrays from ionic chelator-mediated self-assembly. We numerically demonstrate multiplexing and demultiplexing of two distinct chaotic optical signals with strongly overlapped spectra, which are generated by mutually coupled external-cavity semiconductor lasers. As such, they are involved in a number of essential and diverse cellular processes, including division, molecular transport, and the maintenance of structural integrity in the face of mechanical stress. We also demonstrated that Smad1 and ALK1 were highly expressed in human diabetic nephropathy. Here we identify extracellular signal-regulated kinase as the major kinase responsible for TLR-dependent Bim phosphorylation.

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The ability of the antibody to precipitate the transferase was not altered by destroying the secondary structure of the enzyme. Farnesyl phosphates are endogenous ligands of lysophosphatidic acid receptors: inhibition of LPA GPCR and activation of PPARs. This comparative study is levaquin dose in elderly conducted through classifying the protein sequences of five superfamily classes, downloaded from a public domain database. 2-Nitroanisole (2-NA) is an important industrial pollutant and a potent bladder carcinogen for rodents. Heparin-binding protein 44, an antagonist of the LDL receptor family, also suppressed the cell-mediated LDL oxidation in a dose-dependent manner. The presence of D allele in I/D polymorphism of angiotensin converting enzyme gene is associated with progressive deterioration of renal function in congenital uropathies.

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