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Alzopam (Alprazolam)

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Alzopam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alzopam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alzopam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alamflu, Alltop, Almac, Alpaz, Alpram, Alprasert, Alprawin, Alprazan, Alprine, Altin, Alzam, Alzomax, Alzorix, Anxiflu, Anxofit, Anxyl, Balmusa, Betapax, Depwell, Dipra, Dizeral, Elflu, Eurolam, Fledore, Fludep, Hiprazole, Onapract, Optizole, Pronext, Rozin, Silam, Sinzolam, Somnirest, Sowel, Sozox, Tranax, Trustin

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alzopam dosage information


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alzopam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alzopam XR dosage information

Side effects

The most common side effects associated with Alzopam are:

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Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of alprazolam in the elderly. However, elderly patients are more likely to have unwanted effects (eg, severe drowsiness, dizziness, confusion, clumsiness, or unsteadiness) and kidney, liver, or lung problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

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Stable integration of the manA gene into the genome of pearl millet was confirmed by PCR and Southern blot analysis. We genotyped the two polymorphisms in a case-control study of 500 breast cancer patients and 799 age-matched cancer-free controls using the TaqMan method. Assessment of two tests of thyroid function: serum protein bound iodine and radioiodine tracer test. A comparative study on urinary purine derivative excretion of yak (Bos grunniens), cattle (Bos taurus), and crossbred (Bos taurus x Bos grunniens) in the Qinghai-Tibetan plateau, China. Ten of the 14 clinics run by practising GPs attracted more referrals from within their practices than from outside. We employed gene transfection and small interfering RNA to demonstrate that increased delta-catenin expression promoted, whereas its knockdown suppressed prostate cancer cell viability. Additionally, vesicles have promise in the clinical arenas of disease biomarkers, tissue restoration and control of neoplastic cell growth. K252a, an indrocarbazole derivative, causes the membrane of myoblasts to enter a fusion-capable state.

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We present a case of a 61-year-old female patient with ectopic corticotropin (ACTH) syndrome, hypopituitarism, and catecholamine excess due to a paraganglioma at the inferior pole of the left kidney. Our results offer structural and mechanistic insights into PrtH and its homologs, and help classification of this protease family. Professional groups, such as IFAPP (International Federation of Pharmaceutical Physicians and Pharmaceutical Medicine), are expected to produce the defined core competencies to orient the discipline and the academic programs for the development of future competent professionals and to advance the profession. We studied 448 children born in Mexico City from 1997 through 2000, using a longitudinal study to investigate neurotoxic effects of early-life manganese exposure. The pattern of results was consistent with the attentional hypothesis. Several polymorphisms in the IL-4 receptor alpha (IL4RA) gene have been associated with asthma and atopy, but with variable success in different populations. Understanding how CSCs form and how they contribute to the pathology of breast cancer will greatly aid the pursuit of novel therapies targeted at eliminating these cells. In vitro release of tetracycline hydrochloride from alpha-TCP cement.

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Candida endophthalmitis was noted in patients with a history of gastrointestinal surgery, hyperalimentation, or diabetes mellitus, whereas aspergillosis was present in patients who had undergone organ transplantation or cardiac surgery. However, more research is warranted to clarify the incidence of vaccine-preventable infections, harmful effects of vaccination, and the influence of any immunomodulating agents on vaccination efficacy. Visual illusions and plate design: the effects of plate rim widths and rim coloring on perceived food portion size. Negative effects were driven by cancer or its treatment, including physical and psychological effects. However, therapy with a combination regimen that included bortezomib, cyclophosphamide and dexamethasone resulted in complete and durable remission of multiple myeloma and IgA pemphigus. Population-level effects of spinosad and Bacillus thuringiensis israelensis in Daphnia pulex and Daphnia magna: comparison of laboratory and field microcosm exposure conditions. gingivalis which is known to be upregulated under H2O2 induced stress. Proceedings of the anatomical society of great britain and ireland, july 1967. In selected patients, a knee arthrodesis is a well-recognized salvage procedure. Effectiveness of management of diabetic ketoacidosis in the emergency department of a general hospital in Greece.

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Protective effect of supercritical fluid rosemary extract, Rosmarinus officinalis, on antioxidants of major organs of aged rats. Spectrometric oil analysis is an important method to study the running state of power-shift steering transmission (PSST). Genetic compensation, which is consistent with the normal phenotype of the father, was shown through quantitative-expression analyses of genes located within the genetic region associated with the DiGeorge syndrome. AKR/cum and C57BL/6J mice were exposed, in inhalation chambers, to 0.25 ppm NO2 for 7 wk and 0.35 ppm NO2 for 12 wk, respectively. Her-2/neu and urokinase-type plasminogen activator and its inhibitor in breast cancer.

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The magnitude of ventricular hypertrophy in response to afterloading was determined by wall stress, with wall thickness. The cultured primary stem cells were fibroblast-like and showed active proliferation. The co-expression of Rep with either AC4 or C4, expressed from overlapping open reading frames, triggers systemic necrosis in infected-tissues, but AC4 or C4 alone is neither an inducer nor enhancer of the HR-like phenotype. Ether lipid generating enzyme AGPS alters the balance of structural and signaling lipids to fuel cancer pathogenicity. Evolution and heterogeneity of multiple serotypes of Dengue virus in Pakistan, 2006-2011. The survey contained questions about departmental demographics, opinions regarding imaging for patients with cancer, PET/CT utilization, and utilization of the Response Evaluation Criteria in Solid Tumors (RECIST) system in therapy protocols that use imaging as a therapeutic end point. Ex vivo expansion or gene modification of EPCs could be the strategies for the next generation cell therapy to overcome these issues.

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We evaluated the results of reamed and locked intramedullary nailing for tibial diaphysis fractures. The T : LH ratio showed a progressive increase unrelated to rhCG dose or ND suppression, whereas both rhCG and ND suppression minimally increased T : E ratio. The glenoid bare area is a variably visible and eccentric landmark on the glenoid and thus should not be used as the sole reference point to measure glenoid bone loss. Doxazosin provided a safe alternative to phenoxybenzamine in the three cases described, with some advantages that the authors summarize. The results also indicated that an object whose orientation was parallel to its motion path strengthened the spatiotemporal integration of local motion signals along a straight motion path, resulting in the perception of streaming. The methods depend on the favorable match of bimolecular collision rates at micromolar concentrations to nitroxide spin-lattice relaxation probabilities. To study the drug-guiding mechanism of Achyranthes bidentata from Sanmiao pill in arthritic rats. Whether any antibiotic coverage, particularly broad-spectrum coverage, reduces monitor-related infections remains unproved, and exposure to antibiotics may affect the susceptibility patterns of pathogens producing subsequent infectious complications. Algae were obtained from the Nonvascular Plant Laboratory collection, in the Facultad Experimental de Ciencias, Universidad del Zulia, Venezuela.

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The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin. These findings demonstrate that Wnt2 expression and signaling is a common target of antidepressants and that increased Wnt2 is sufficient to produce antidepressant effects. Detection of low-level mosaicism by array CGH in routine diagnostic specimens. The RT-PCR results showed that tissue distribution of HQT was in accordance with the pattern of CGA content. Thermometry testing of two different waterbolus geometries demonstrated that uniform circulation and temperature control can be maintained throughout large, complex bolus shapes.

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Biomedical Engineering education has become very popular in the past two decades. The effect of ethionine on the energy-producing metabolism in the rat pancreas. Up until now, the mechanism of action of 26RFa in the hypothalamic control of food intake remains unknown. Although cardiac taurine is only a small fraction of the taurine in the rest of the body in all animals studied, the concentration of taurine in the heart is similar to that in the rest of the body (40-45 nmole/mg freeze-dried wt) in embryos through Day 14.5 of gestation. Azelnidipine inhibits aldosterone synthesis and secretion in human adrenocortical cell line NCI-H295R.

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The presence of WPW only in the term infants may account for differences in the clinical course between preterm and term infants. The main points in the discussion on the possibility of application of epidemiological methods to evaluation of health promotion programmes are mentioned. Supporting the proposed definition of normovolemia, non-fasting, supine, healthy subjects are provided with a preload to the heart that does not limit SV suggesting that the upper flat part of the Frank-Starling relationship is reached. DNA binding by adriamycin, melphalan, cis-dichloro-diammineplatinum (II) and nornitrogen mustard assessed by restriction enzyme block. The process of shared development and local experimentation resulted in EQ-5D, a generic measure of health status that provides a simple descriptive profile and a single index value that can be used in the clinical and economic evaluation of health care and in population health surveys. Ecological study of effect of breast feeding on infant mortality in Latin America. The protocol is designed to allow for delivery of predictable electrical field stimuli to cells, monitoring environmental parameters, and assessment of cell and tissue responses. We examined the experience of 10 distinct cohorts of new users of diclofenac, naproxen, ibuprofen, piroxicam, other NSAIDS, meloxicam, celecoxib, etoricoxib, rofecoxib and valdecoxib.

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During 1984 and 1985, six Rift Valley Fever virus strains (RVF) were isolated in Central African Republic, among them five from human samples. Weight, body composition (bioelectric impedance analysis), adrenal and gonadal hormones, and sexual functioning (questionnaire) were measured. On the other hand, there are large differences in the incidence between populations, which support hypotheses about the life style, especially of diet, as a risk factor for breast cancer. A proteomic study on cell cycle progression of endothelium exposed to tumor conditioned medium and the possible role of cyclin D1/E. A 6-year-old boy developed symptoms of rapidly progressive paraplegia, associated with bowel and urinary dysfunction, but without sensory loss.

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Mucoidy was restored in the kinB algB double mutant by expression of wt AlgB or phosphorylation-defective AlgB.D59N, indicating that phosphorylation of AlgB was not required for alginate overproduction when kinB was inactivated. Efficient Rh(I)-catalyzed direct arylation and alkenylation of arene C-H bonds via decarbonylation of benzoic and cinnamic anhydrides. MD provided similar or slightly better clinical outcomes with less complication as compared to DV. For this treatment, biological as well as synthetic materials are available. This shows that our ability to correctly interpret trajectory data is extremely sensitive to the geometry and timing of the experiment, the degree of motility bias and the number of experimental replicates. This provides a novel perspective for analysis of the pathophysiology of cerebral ischemia. A retrospective evaluation was performed on BM specimens from eight autopsied patients from Botucatu University Hospital with PCM-related BMN. Using data for serotonergic (5-HTTLPR, MAO-A) and dopaminergic (DARPP-32) genes as examples, we show that systems-level connectivity networks under genetic control can be identified. The results showed that local processing primed subordinate object discriminations when the objects were visually similar. Several splicing factors, including SAM68, have pro-oncogenic functions, and their increased expression often correlates with human cancer development and progression.

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EI could prevent neuronal ischemic injury by inhibiting activation of PKC. Sepiolite, a member of the fibrous mineral group of clays, is relatively free of surface ferric iron and does not accelerate significantly the oxidative degradation of hydrocortisone. The human epidemiology indicates an inverse correlation between high fiber consumption and lower colon cancer rates. Reductions in the incidence of nitrofen-induced diaphragmatic hernia by vitamin A and retinoic acid. Review of the pertinent literature showed no documentation of AV malformation in the maxillary sinus, and therefore we present the case of a 43-year-old white man with a history of blunt trauma to the paranasal region, whose differential diagnosis included a vascular lesion. In seven patients the first heart sound was loud preoperatively and was associated with delayed mitral valve closure. Sucrose density gradient centrifugation and immunostaining of caveolin-1 revealed that p122 was localized in caveolin-enriched membrane domains mainly via its GAP domain. Idiopathic osteoporosis of the femoral head is a condition that mimics osteonecrosis of the femoral head and can be a challenge in diagnosis during the latter stages of pregnancy.

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These visual cues display information of proximity, contact and effort between virtual objects when the user manipulates a part inside a digital mock-up. Ying-Yang flap technique for correction of male nipple hypertrophy: a case report and a review of the English-language literature. Planning adenotonsillectomy in children with obstructive sleep apnea: the role of overnight oximetry. The tumor specimens were checked for estrogen receptor (ER), progestrone receptor (PR), and HER2 status by immunohistochemical stain. Lack of endogenous modulation and reduced decay of prolonged heat pain in older adults. As costs continue to outpace reimbursements, hospital administrators and clinicians face increasing pressure to justify new capital purchases.

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The unusual aspect of this malfunction was the finding of disc dislodgment despite the absence of pathology in the disc itself. Pml and TAp73 interacting at nuclear body mediate imatinib-induced p53-independent apoptosis of chronic myeloid leukemia cells. The simulated muscular paralysis time curves, calculated for various modes of NMBA administration (loading injection and multiple injections or continuous infusion) are comparable to those observed clinically. We have recently established a new method for bone marrow transplantation (BMT) in mice: bone marrow cells are directly injected into the intra-bone marrow (IBM) cavity. Association between long working hours and sleep problems in white-collar workers. To investigate if the pull-out strengths after cyclic uniplanar loading of cervical pedicle screws are superior to lateral mass screws. The WT-MCF-7 cells showed abundant expression of caveolin-1 which potentiated oestrogen-receptor (ERalpha) signalling and promoted cell growth despite caveolin-1 mediating inhibition of ERK signalling. It has been many years now since the introduction of nerve transfers for repair of traumatic brachial plexus lesions and more recently, we have seen its application in the field of obstetric brachial plexus palsy. Age groups were compared on: Pavlovian fear conditioning and extinction, anxiety-like behavior and exploratory locomotion (using elevated plus-maze and novel open field), and depression-related behavior (via forced swim test).

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The technique allegra 120 mg dosis adultos of rapid PRINS could be used to detect chromosomes in frozen section tissues, and the chromosomal abnormalities would be helpful in diagnosis of NPC. Podocytes play a key role in the maintenance of the glomerular filtration barrier. To study the safety and efficacy of continuous intratympanic dexamethasone-phosphate (Dex-P) for severe to profound sudden idiopathic sensorineural hearing (ISSHL) or sudden idiopathic anacusis after failure of systemic therapy. One strategy for incorporating the perceptions is community-based participatory research. Beta 2-adrenergic receptor supercoupling with desensitization on isoproterenol exposure. High-density marker imputation accuracy in sixteen French cattle breeds. Lipid and fatty acid contents of the cells were also determined. Human body surface area (BSA) is the preferred denominator for physiological indices of body metabolism and for drug dosages.

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Campylobacter jejuni and Campylobacter coli strains were isolated from feces of dairy cattle at farms with no known problem due to campylobacteria. All MAbs detect fecal antigens starting the second to third week post infection (wpi), although it was less clear with MAbs 4B1 and 4B2, while circulating antigens were detected from third to fourth wpi. The arrays were designed for the screening of high-surface-area supported electrocatalysts. Isolation of kidney antigen in the blood and urine of recipients in kidney transplantation. A new molecular thermodynamic model is developed for multicomponent Ising lattice based on a generalized nonrandom factor from binary system. So far, monoclonal antibodies, immune conjugates, tyrosine kinase inhibitors, immunomodulatory agents, and other therapies have been tested in the phase 2 or phase 3 setting for the treatment of metastatic melanoma. The following organelles were examined: 1) mitochondria, 2) Golgi apparatus, 3) endoplasmic reticulum, and 4) free polysomes. Neurophysiological study of a group of workers exposed to industrial heptane in a rubber shoe factory. Proceedings of the anatomical society of great britain and ireland, april 1967.

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During infusion of iodoantipyrine, radioactivity in an external femoral arteriovenous loop is monitored by a scintillation detector. Hemianopsias in cortical and subcortical lesions of the visual system: what is the difference?. The content and frequency of the routine dental examination are discussed in relation to theolair 250 mg the individual risk prediction as relevant aspects of quality of dental care in the Netherlands. Data of crop seeds with regard to four seed traits and four yield traits based on the modified diallel crosses in Upland cotton (Gossypium hirsutum L.) were used as an example for demonstrating the proposed methodology. LMW-INH inhibited C3 convertase formation in fluid phase, on sheep erythrocytes and on zymosan particles. Enamel and dentin discolouration were verified using microscopy and transmission spectroscopy. Professional judgment or ill-concealed contempt for the patient?. In this article the cerebrovascular physiological control is reviewed in relationship with possible EDRF actions. Building and teaching bioethics in francophone countries: at the crossroads of disciplines and practices, April 7 to 9, 2011, Belgium.

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Varicella pneumonia with immune thrombocytopenic purpura: a patient with multiple complications. With best distance correction near visual acuity in MIOL was statistically significant better than in all 4 MONO categories. Details on drug photoreactivity will also be helpful in order to minimize side-effects and/or optimize drug targeting by developing photoresponsive drug delivery systems. A systematically selected representative sample of 455 70-year-old ambulatory individuals was prospectively followed for 12 years. Glasgow Coma Scale severity scores and the duration of altered consciousness were related to performance on several major neuropsychological functions. Accurate preprocessing of digital data is crucial for measurement accuracy, especially when subtle structures such as trabecular bone are investigated. Quantitative histochemical measurement of GABA-transaminase: method for evaluation of intracerebral can i take tetracycline while breastfeeding lesions produced by excitotoxic agents. The structural factors that have the most pronounced effect on A and E(a) are considered, and the presence of rings is shown to influence these values strongly. compartmental modeling when two accessible pools are available in kinetic experiments. Furthermore, a significant correlation between childhood obesity and the presence of hypertension, spinal deformities and foot deformities were also observed.

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Further research is necessary in order to elucidate the effects of different antipsychotic agents on antioxidant enzymes and lipid peroxidation or possible interventions at the oxidative stress level in schizophrenic patients. Autopsy studies show the uniquely high prevalence rates of small, indolent tumors in men dying of other causes. Decision support for governing boards of integrated delivery networks: explicating versus eliciting knowledge. Given the significant but complex association of comorbid medical conditions with depressive symptoms in aged persons, clinicians should exercise care to address their physical and mental health needs within a common therapeutic context. There were no obvious differences in the total amount of antibiotics dispensed over the years that could be related to influenza activity, but a coincidental relationship between the peaks of diagnosed influenza cases and the peaks of antibiotic utilization was indicated, especially for older age groups.

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However, the behaviour problem scores in children with cardiac disease are significantly lower than in healthy children. Cell proliferation activity was analyzed using cell counting kit-8 (CCK-8), cell cycle was detected by flow cytometry, and the protein expression of cyclin D1, p21 and Bcl-2 was detected by Western blot analysis. Three-dimensional computed tomography analysis and anteversion study after periacetabular osteotomy of pelvis in children. A priori comparisons and Analysis of Variance resulted in the finding that persons with MS who were employed tended to rate their levels of QOL nearly one third of a standard deviation higher than their unemployed counterparts. Liver metastasis of a mucinous colonic carcinoma mimicking a haemangioma in T2-weighted sequences. Hermansky-Pudlak adipex 75 mg syndrome and Chediak-Higashi syndrome: disorders of vesicle formation and trafficking. (4) The adverse effects of temozolomide include gastrointestinal disorders (nausea, vomiting, constipation), headache, and haematological disorders. Viewed collectively, these observations indicate that in vivo exposure to nicotine or to tobacco smoke augment PMN superoxide anion generation and chemotactic responses to selected stimuli and thus implicate such adverse actions of smoking on PMN function in certain pathologies associated with excessive tobacco smoke exposure.

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