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Ambusyn (Alprazolam)

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Ambusyn is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Ambusyn, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Ambusyn is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alltop, Alpam, Alprasert, Alprastan, Alprazolam, Alprowon, Alrif, Alsert, Altin, Alzolite, Ambulax, Anilam, Anxigon, Anxofit, Elflu, Fledore, Imprax, Isorest, Nucalm, Pecalm, Plxna, Proprazolam, Resta, Resto, Rezolam, Selamb

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Casodex, Bactrim, Feldene, Lexapro, Viagra, Vantin, Mellaril, Uroxatral, Ditropan, Alfusin, Albenzole, Befine, Elpam, Zanaflex, Avizin,

Also known as: Alprazolam


Ambusyn is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Ambusyn is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Ambusyn if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Ambusyn or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Ambusyn. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Ambusyn. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Ambusyn XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Ambusyn XR dosage information

Side effects

The most common side effects associated with Ambusyn are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Ambusyn from your body, which may affect how Ambusyn works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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WSN based mobile u-healthcare system with ECG, blood pressure measurement function. Subcellular localization of transiently expressed fluorescent fusion proteins. GFP expression was monitored in frozen testes sections by fluorescence microscopy. To evaluate the apical microleakage of Thermafil obturations after three different post space preparation techniques. This complex is greatly diminished in the nine non-myocyte cell types, where a different complex predominates. A primer set for the assay was designed on the basis of the sequences between the 17AA and KTS regions of WT1mRNA. Serum retinol-binding protein 4 is inversely correlated with disease severity of chronic hepatitis C.

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CuI-catalyzed coupling reaction of beta-amino acids or esters with aryl halides at temperature lower than that employed in the normal Ullmann reaction. Comparison of tonsillar biofilms between patients with recurrent tonsillitis and a control group. First, what was the magnitude of increased incidence of thyroid cancer in Canada from 1991-2006?. A new membrane model derived from a study of filaments, microtubules and membranes. A second addition of gamma-BHC to one of the nonsterilized soils. BALB/c (H-2(d)) recipients were transfused with blood from either C57BL/6 (H-2(b)) or MHC II null donors on a C57BL/6 background. Current concepts regarding the pathogenesis of necrotizing enterocolitis.

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The Min system regulates the positioning of the cell division site in many bacteria. The direction and magnitude of nondifferential exposure misclassification (the type most likely to occur in cohort studies) on estimates of relative risks can be largely predicted given knowledge on the degree of misclassification, that is, relatively small amounts of misclassification can bias relative risks substantially towards the null. We evaluated the blood and effect-site concentrations of propofol and fentanyl calculated by a pharmacokinetic simulation model in which the administration of one drug was managed with target-controlled infusion pump set for another drug. The contralateral lateral reticular (LR) nucleus and nucleus cuneatus (CU) were activated. We included prospective studies of diagnostic accuracy that compared at least 1 physical examination maneuver with radiographic confirmation of pleural effusion.

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Lymphocytes from uremic patients showed statistically significantly lower (P less than 0.01) MLC reactivity against pooled stimulator cells as compared with lymphocytes from age matched controls. After bud break, the number of eggs per female increased and all nematode stages were found in host roots. Increased understanding of nutrient immobilization in soil organic matter is critical for predicting the carbon sink strength of forest ecosystems over the next 100 years. However, the original MDR method classifies the combination of multilocus genotypes into high-risk and low-risk groups in an ad hoc manner based on a simple comparison of the ratios of the number of cases and controls. Evaluation of specific biological heat potential of oily wastewater in an autothermal thermophilic aerobic treatment system. Although such a problem does not undermine the importance of cyclooxygenase 2 as a cancer chemopreventive target, investigation into other AA-metabolizing pathways that are also important in inflammation and inflammation-associated carcinogenesis is necessary. Thiazole orange-positive platelets in healthy and thrombocytopenic dogs. Among them, compounds 14f and 14i display the most promising potency with EC(50) values of 0.21 and 0.17 microM respectively. Increasing the number of synapses modifies olfactory perception in Drosophila.

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Chemical effects provide 1-2 orders of magnitude enhancement, whereas electromagnetic effects yield up to 6 orders of magnitude enhancement for CN(-) or 5 for HCN. Intra-operative evaluation of cementless hip implant stability: a prototype device based on vibration analysis. Beta-hCG has been purified and also produced by monoclonal antibodies, and shown to produce antibodies and infertility in baboons. The future may find certification examinations necessary for all research staff, including investigators. These changes in breathing pattern was not associated with a significant decrease in alveolar CO2 pressure and did not seem to be responsible for important variations in respiratory gas exchanges. Programs for estimation and for simulating from these models on a whole-genome basis are described and provided. Room-temperature electroluminescence in the mid-infrared (2-3 microm) from bulk chromium-doped ZnSe. Acute reduction in aortic compliance results in a significant increase in characteristic and input impedance, a significant decrease in systemic arterial compliance and a subsequent increase in systolic and pulse pressures leading to left ventricular hypertrophy. The patients were enrolled in a maintenance program including professional tooth cleaning every 2 to 4 weeks. An interesting effect of this is the change of the nature of the carbon-carbon double bond of the lactam ring from vinylic to aromatic.

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mRNA levels for cyclin A2 and cyclin B1 were elevated by approximately 2-fold at 72 h. Can we, however, consider the advent of bioethics as a form of progress marking the advances made in biomedical science with an adequate ethical stamp?. A method to rescue dystrophin production by antisense oligonucleotides, termed exon-skipping, has been reported for the mdx mouse and in four DMD patients by local intramuscular injection. We still recommend asthmatics as a priority group for influenza vaccination and treatment. Antimicrobial activity of Argentine plants used in the treatment of infectious diseases. During contrast injection into a peripheral vein, microcavitations that passed from right to left at the atrial level were seen filling the vein of Galen aneurysm. Treatment consists in laparotomy which enables better vascular control. The bacterial actin homolog ParM catalyzes segregation of plasmid DNA in E. Incidence of unwanted effects of dihydrocodeine bitartrate in healthy volunteers.

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A meta-analysis of TP53 codon 72 polymorphism and lung cancer risk: evidence from 15,857 subjects. Infective- and vertebrate-stage trypomastigotes of Trypanosoma cruzi resist serum killing by the alternative complement pathway, whereas noninfective vector-stage epimastigotes, from which trypomastigotes derive, are serum-sensitive. Suspected of being the infective stage, cysts were studied in more detail as regards their morphology using both light and electron microscopy. The effects of two cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitors on proliferation of cell lines representing different stages of mouse skin tumorigenesis were studied. Firstly, gamma ERS caused by the imagination of body parts movement appears at near somatosensory area and motor area. A 69-yr-old retired fisherman with rapidly progressive necrotizing fasciitis from Photobacterium (Vibrio) damsela infection and ensuing multiple-system organ failure. Selective intra-arterial perfusion of the cancerous breast: quantitative study. The thromboxane A2 analog U46619 (3 x 10(-7) m) induced more marked increases of platelet P-selectin expression and platelet-leukocyte aggregation in DM patients than in healthy subjects. Identification of a splice variant of mouse TRPA1 that regulates TRPA1 activity. heteroclitus gonadotropic hormones (GtHs) I and II have been sequenced, and antibodies have been raised against unique peptides found in each of the two beta subunits.

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The origin of the oil contained in the emulsions played an important role on the efficacy. However, since it limits motion and forces the remaining joints to absorb more load, long-term studies report diminishing results over time from symptomatic breakdown of adjacent joints. It further highlights a few of the many recent applications of electrospun nanofiber scaffolds in repairing and regenerating various orthopedic tissues. The study included record-linkage to national mortality datasets to identify fatal events. In the terminal bronchioles, a trachea-like pseudostratified epithelium develops with p63-positive cells underlying columnar cells.

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Southern blot analysis of alphoid repeat DNA on the chimpanzee X chromosome suggests this subfamily has been strongly conserved during and since the separation of chimpanzee and man although the two subfamilies can be distinguished on the basis of Taq I restriction fragments. Mechanistic aspects of DnaA-RepA interaction as revealed by yeast forward and reverse two-hybrid analysis. Taken together, these results demonstrate that proangiogenic signals converge to enhance expression and association of RACK1 and vimentin, which regulated FAK, resulting in successful endothelial sprout formation in three-dimensional collagen matrices. This article has been withdrawn at the request of the author(s) and/or editor. Treatments with low floral temperature did not reduce stigma receptivity or pollen viability in undehisced anthers.

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The results are discussed in terms of cultural, religious, ethnic, and socioeconomic influences. Last, an increased rate of energy expenditure protects PML KO mice from the effects of obesity induced by a Western diet. The viability of the coupling is demonstrated with a three-dye mixture composed of fat red 7B, solvent green 3, and solvent blue 35 separated and eluted from a silica gel-coated rotor using toluene. The present study was designed to examine whether neuroprotective agents, FK506 or cyclosporin A (CsA), applied to rats undergoing pilocarpine-induced seizures can minimize further development of the status epilepticus. Methotrexate binding to dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli. Conjunctival neuromas and prominent corneal nerve fibers as diagnostic indication of multiple endocrine disease. To elucidate the significance of this pathway, we recorded spikes of IO neurons in four awake Japanese quail using an implanted electrode assembly while recording unrestrained head movements. The five strains, including one spirochete and four Betaproteobacteria strains, were isolated by the filtration-acclimatization method.

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Novel initiatives of the National Institutes of Health to support congenital heart disease research. This study supports the action of ROCK on learning and memory, suggests tetracycline allergy and penicillin the potential value of ROCK inhibition for the promotion of cognition in humans, and highlights the powerful potential of unbiased genome-wide association studies to inform potential novel uses for existing pharmaceuticals. High SES patients reported better outcomes at the premorbid assessment with fewer depressive feelings and better physical functioning. Novel H1N1 influenza and Panton-Valentine leukocidin Staphylococcus aureus necrotizing pneumonia. These lytic antibodies are immunoglobulin G (IgG) and in high titres cause haemolysis during blood transfusion. Because the source code is openly available, these functionalities can now be used to build derivative applications in relatively fast manner. Physiological outcomes include neurogenesis, neuronal differentiation, glial proliferation, migration, growth arrest and apoptosis. Published studies presenting similar analyses suggest that our results could have generality across different biogeographical settings and types of organisms.

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Opposite to these findings, GSHPx was significantly increased in mitochondrial membranes of EFA-deficient animals. The nasal mucosa provocative tests and nasal airway resistance and subjective nasal patency feeling were studied before and after plasma radiofrequency ablation treatment. To evaluate the impact of rotational setup errors on dose distribution in spinal stereotactic body radiotherapy (SBRT). Cells morphologically intermediate between mucosal mast cells and bulin. The synthesis and fluorescence properties of a naphthalenediimide ditosylate are presented. Cellular localization of the protein, ChSir2, was analyzed by the use of the social amoeba Dictyostelium discoideum as a model system. Practice Nurses largely welcomed the potential development of their role in this area, but identified barriers and training needs which must be addressed to enable them to feel confident managing of patients with this condition. Since image acquisition, reconstruction and evaluation parameters influence the results of calcium quantification with CT techniques, standardization of the investigation is mandatory to make results comparable. Three patients with neonatal herpes simplex virus (HSV) infection with upper or lower respiratory tract involvement are described.

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Disturbances of platelets function in patients with multiple myeloma. The formulation and implementation of effective health service provision policies must be underpinned by overarching health goals, agreed health service requirements, recognition of how rural and remote health contexts impact upon health service provision and the constraints limiting health service responses. Infrapopliteal balloon angioplasty for chronic critical limb ischemia in diabetic patients with uremia: when is it worth the effort?. MEDIS has explored a federated, component-based EHCR architecture and related security aspects. The mean pain scores at 0, 6, 24, and 48 hours postoperatively, the demographic characteristics, and the stones characteristics were evaluated to determine the feasibility. Signal peptidase complex subunit 1 participates in the assembly of hepatitis C virus through an interaction with E2 and NS2. In this paper the result of application of SIMLII guide lines on upper extremity work related ultram 50 mg tablet musuloskeletal disorders in different work conditions are presented and discussed. Effects of the association of aging and obesity on lipids, lipoproteins and oxidative stress biomarkers: a comparison of older with young men. Every paragraph is accompanied by a certain level of a recommendation strength (RS, A-C). We conclude that chromatin remodeling, which provides accurate models of gene expression and morphological variations, may help to find the biological marks that cannot be detected by genome-wide association study or genetic study.

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The structures of lignins were studied by three non-destructive (FT-IR, solid state (13)C NMR and UV/visible spectroscopy) and two destructive (nitrobenzene oxidation and thermogravimetric analysis) methods. Susceptibility of chicken blood lymphoblasts and monocytes to infectious bursal disease virus (IBDV). HMG-CoA reductase is regulated by environmental salinity and its activity is essential for halotolerance in halophilic fungi. Hippocampal seizure discharge produced by systemic digitoxigenin is antagonized by reserpine or p-chlorophenylalanine. Acquired immunodeficiency syndrome research in critical care: a review and future directions.

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Vaccination was an important component of this immunotherapy, as it resulted in enhanced and prolonged tumor-specific CD8 T-cell activity and improved antitumor efficacy. All four genes are expressed with a striking asymmetry about the left-right axis in the pharyngeal region of neurula embryos, mirroring the pronounced asymmetry of amphioxus embryogenesis. Furthermore, CYP1A1 down-regulation was accompanied by a reduced ability feldene medicine drug interactions of oocytes to complete in vitro maturation until metaphase II stage. Sensitive enzymatic analysis of histidine decarboxylase using HPLC. Hyperacute rejection can be prevented by using donors in which GalT, the gene responsible for the predominant target of anti-pig natural antibodies, has been deleted. Here, we measured genome-wide DNA accessibility in Drosophila melanogaster by combining M.SssI methylation footprinting with methylated DNA immunoprecipitation. This is the first report on the isolation and characterisation of EHV-1 in Colombia.

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Other intrathyroidal neuropeptides, such as substance P and CCK-4, have been found to be without effects on iodothyronine secretion, but, like VIP, to stimulate calcitonin secretion. For this reason, the therapeutical solutions must have in view rapid restoring of the passive and active movements of the elbow. We found a low prevalence of positive skin tests with mouse antigen. The pleopods became functional beginning with the first post-larval stage. ACA threatens to increase government involvement in the practice of medicine. We investigated whether the left adrenal vein could be consistently localized on three-dimensional (3D) real-time volume nizoral generic shampoo -rendering computed tomographic angiographic (CTA) mapping in a group of living renal donors before laparoscopic nephrectomy. Invasive micropapillary carcinoma of the breast: high incidence of lymph node metastasis with extranodal extension and its immunohistochemical profile compared with invasive ductal carcinoma. Abnormality of the radial migration was caused by the reduction of radial fibers in the radial glias. Search for x-ray induced acceleration of the decay of the 31-yr isomer of (178)Hf using synchrotron radiation.

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Efficacy of peritoneal dialysis with icodextrin in the long-term treatment of refractory congestive heart failure. Further attempts to characterize the normal incomplete cold antibody. The conditions which might favour development of the fibrotic or the lipid component of the pulmonary reaction to inhaled quartz were examined in rats. Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting. The ventilators are cheap and reliable, with a stable performance but more sophisticated patterns of ventilation necessitate the use of volume and pressure monitoring. Nevertheless, this is acceptable because the operation in active phase is enforced by life-threatening complications and it also reduces assumed mortality at conservative therapy. A daily supplement of 1.17 mmol potassium-chloride (KCl) per kg body weight was given to the subjects in the SCS and SES groups.

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