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Amebidal (Metronidazole)
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Amebidal

Amebidal is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Amebidal, Anerobia, Asuzol, Clont, Colpofilin, Corsagyl, Elyzol, Entizol, Farnat, Filmet, Flagemed, Flagenase, Fortagyl, Gynomix, Mecozol, Menizol, Metrazol, Metrogel, Metronidazole, Metronidazolum, Metrosil, Metrozol, Metsina, Nidazol, Nipazol, Norzol, Novazole, Perilox, Promuba, Robaz, Rovamet, Suanatem, Trichazole, Vagimid, Vandazole, Varizil, Vertisal, Zidoval

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Also known as: Metronidazole

Description

Amebidal (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

Amebidal is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use Amebidal to treat any condition that has not been checked by your doctor.

Dosage

This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amebidal. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Amebidal overdose, Amebidal infusion should be discontinued. Patients should be treated symptomatically.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metronidazole topical dosage information

Side effects

The most common side effects associated with Amebidal are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of metronidazole capsules and tablets in the pediatric population, except for the treatment of amebiasis. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of metronidazole extended-release tablets to treat bacterial vaginosis in teenage females, but should not be used before the start of menstruation.

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NGS meta data analysis for identification of SNP and INDEL patterns in human airway transcriptome: A preliminary indicator for lung cancer. The study aimed at developing a scoring system for scintigraphic grading of gastro-esophageal reflux (GER), on gastro-esophageal reflux scintigraphy (GERS) and comparison of clinical and scintigraphic scores, pre- and post-treatment. Fifteen single-nucleotide polymorphisms (SNPs) in 12 candidate genes previously reported as OA susceptibility loci were selected for investigation. Carbon Dots as Fillers Inducing Healing/Self-Healing and Anticorrosion Properties in Polymers. These could be purified by liquid chromatography and were shown to have identical amino acid compositions. Effects of hemodilution on splanchnic perfusion and hepatorenal function.

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Hepatitis C virus and chronic hepatopathies in Dakar: case-control study. Preparation of training base in Izhevsk in 1941 for evacuation of Moscow State Dental Institute. Laparoscopic Roux-en-Y gastric bypass is effective in achieving weight loss and in improving comorbidities and quality of life while reducing recovery time and perioperative complications. Unlike the methyl ester of 1, the ethyl ester of 3 is not intermolecularly hydrogen bonded in nonpolar solvents. Sofosbuvir and Simeprevir Treatment of a Stem Cell Transplanted Teenager With Chronic Hepatitis C Infection. The tractograms of patients with paralyses clearly showed the degeneration of nerve fibers and were correlated with clinical symptoms. Clozapine was analyzed, and its major metabolites, clozapine N-oxide (CNO) and N-desmethylclozapine (NDMC), were identified and quantified. Agonists (isoproterenol or nitroprusside) were used to stimulate adenylyl cyclase and guanylyl cyclase, respectively, in the absence and presence of nonselective IBMX or PDE5 specific inhibitors E4021 (1).

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Novel antimicrobial activities of a peptide derived from a Japanese soybean fermented food, Natto, against Streptococcus pneumoniae and Bacillus subtilis group strains. The average age was 60.6 years (range, 41-82) with 41 females and 33 males. The protein and/or mRNA expressions of inflammation factors, monocyte chemoattractant protein (MCP)-1, vascular cell adhesion molecule (VCAM)-1, nuclear factor-kappa B (NF-kappaB) and tumor necrosis factor alpha (TNF-alpha) were investigated by immunohistochemistry and RT-PCR. An evaluation of the effects of ethacrynic acid separately and in combination with atoxyl. There were no differences in procollagen gene expression, total procollagen synthesis, accumulation, or degradation in cardiac fibroblasts treated directly with cyclosporine A, in concentrations up to 1,000 ng/mL, compared with untreated cells. The clinical observation of a patient who presented an association of recurrent meningitis, unilateral deafness, and congenital anomaly of the ear is presented. The S-nitrosation reaction and its reverse reaction represent the most convenient general way to store, to transport and finally to release NO.

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The electrophoretic profiles of the lactate dehydrogenase isoenzymes from the matrix vesicle and matrix vesicle-like vesicles were identical with those of chondrocyte cytosolic lactate dehydrogenase. An experimental platform of two coupled water tanks with a wireless sensor node is established to evaluate and verify the proposed transmission scheme. Using a modified-Delphi procedure, a panel of experts met initially to analyze the content of 95 health-related work outcome measures and organize the identified areas of measurement into a coherent model, complemented by a narrative review of the literature. Positive Youth Development Among Diverse Racial-Ethnic Children: Quality Afterschool Contexts as Developmental Assets. This longitudinal study examined if the evolution of supportive care needs differed over the first year following the diagnosis of advanced breast cancer and examined factors differentiating these trajectories. All Missouri nursing home facilities were included for the analysis of the 14 QMs downloaded in February 2004. Molecular detection of vector-borne pathogens in dogs and cats from Qatar. Controversy continues regarding an association between obstetric complications and risk of schizophrenia in early adult life. Recent genetic studies in Drosophila have begun to clarify the function of HSPGs in vivo and recent findings have implicated HSPGs in Wnt, Hedgehog, fibroblast growth factor and transforming growth factor-beta signaling pathways during development. More definitive clinical trials are currently under way to determine whether this form of therapy, which may diminish the extent of ventricular enlargement over time, will result in an improvement in survival and in the prevention of the development of congestive heart failure.

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On the basis of these findings, we suggest that dopamine beta-hydroxylase- and neuropeptide Y-immunoreactive nerves may be involved in the regulation of airway and vascular diameter in equids. Dopaminergic control of serotonergic neuron development in the grasshopper central nervous system. Each of these themes includes the sub-themes of facilitator and/or barrier. Determination of the open reading frame(s) of novel genes, and extensive analysis of the proteins they encode, can open up new avenues of research and promote intelligent design of downstream projects. In 46 patients, transrectal sonography was performed in addition to transabdominal sonography if pain was localized to the mid lower abdomen and if a disease process could not be visualized or could be only partially visualized on transabdominal examination. Similarly, in the in vivo experiments, 1 h after the acute subcutaneous administration of 0.4 mg/kg of CP55,940, both spontaneous motility and chemotaxis were reduced. These are the difficulties associated with trying to set priorities in ways which are effective and politically acceptable, and the relationship between the public and private sectors. Phase I and preliminary phase II evaluation of adriamycin (NSC 123127). Small clear cell tumors often fail to show the CT characteristics that would permit an accurate classification. DSLNB is a useful and reliable technique to identify the involved node(s) in patients diagnosed as having carcinoma penis with clinical N0 status (with or without palpable nodes).

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Although the mechanisms for these beneficial effects have not been precisely delineated, synthetic PG analogues have increasingly been used in patients with acute liver failure and chronic liver disease. The physiochemical properties and pH-dependent drug release of HA-CHEMS vesicles were evaluated. The rapid evolution of the stent has often made its evaluation problematical, since trials are frequently confined to small groups of patients in single centers. Taken together, plasma-sprayed sphene coating on Ti-6Al-4V possessed excellent bonding strength, chemical stability and cellular bioactivity, indicating its potential application for orthopaedic implants. Transport of glucose across the plasma membrane by GLUT-4 and subsequent phosphorylation of glucose by hexokinase II (HKII) constitute the first two steps of glucose utilization in skeletal muscle. These structures can have potential application as carrier for medicine to involve into metabolism of living cell. To highlight the salient magnetic resonance imaging (MRI) features of the intraneural ganglion cyst (INGC) of various peripheral nerves for their precise diagnosis and to differentiate them from other intra and extra-neural cystic lesions.

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We examined the characteristics of RRT calls to obstetric patients at a tertiary teaching hospital. Differences among the panel of variants were observed in processing of the nonstructural polyprotein and in the ratios of subgenomic to genomic RNAs. The liver is a common site of pathology in HIV-infected patients. Eight weeks of progressive RT did not decrease the group mean values of arterial stiffness in individuals with MetS or healthy controls. However, there seems to be evidence of benefit in women with a history of recurrent miscarriage. Collectively, stress caused significant behavioral and oxidative alterations via suppression of neuronal functions of the central dopaminergic system. An electron microscopic localization of calcium in the small intestine of normal, rachitic, and vitamin-D-treated rats. An extract of Harding-Passey mouse melanoma was found to inhibit the proliferation of the same cell line grown in culture when measured by both thymidine incorporation and by the increase in cell number.

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Quantitation was performed by comparison of the area of the molecular ion of the parent drug (m/z 86) to that of the calibrated deuterated analogue (m/z 92). The model is applied on the Longitudinal Ageing Study Amsterdam (LASA). Patients affected with the distal mutations have a more severe phenotype than do those with the proximal mutation. NIMA expression also induces Ser-10 phosphorylation inappropriately in S phase-arrested cells and in the absence of NIMX(cdc2) activity. We find that nitrogen becomes totally opaque above 150 GPa, accompanied by the disappearance of bactrim and birth control pills interaction Raman and IR vibrational excitations, while new broad IR and Raman bands become visible. Renal artery dissection may be caused by iatrogenic injury, trauma, underlying arterial diseases such as fibromuscular disease, atherosclerotic disease, or connective tissue disease.

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Intracellular membrane-bounded organelles of eukaryotic cells transiently contact the extracellular environment during endocytosis and secretion. Anxiety and new onset of cardiovascular disease: critical review and meta-analysis. These findings strongly suggest that not only retinol but also retinoic acid plays an important biological role in mannosyl transfer reaction in rat liver. A case of brain abscess due to Entamoeba species, Eikenella corrodens and Prevotella species. Confocal laser scanning microscopy demonstrated that phosphorylated AP2 complexes were found more evenly distributed at the plasma membrane compared to non-phosphorylated AP2 complexes which were found in aggregates. We report a typical presentation of eosinophilic fasciitis that developed vasculitic-like leg ulcerations as seen in scleroderma. Starting in 1959, the Unit took the lead in a world campaign to control lung diseases due to asbestos.

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High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid. Detection of Leptospira DNA in urine and presence of specific remeron mirtazapine 15 mg tablet antibodies in outdoor cats in Germany. Nuclear quality control of RNA polymerase II ribonucleoproteins in yeast: tilting the balance to shape the transcriptome. Laboratory and other basic research: delayed examination of gastric washings for tubercle bacilli. These developments, coupled with research into new ways of sampling representatively from both the condensed and gaseous phases, are positioning mass spectrometry as an essential technology for on-line process optimization, understanding and intelligent control. Phylogenetic relationships among species of Pichia, Issatchenkia and Williopsis determined from multigene sequence analysis, and the proposal of Barnettozyma gen. Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps.

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The coronary care unit, general medical wards, and cardiorespiratory department of a major teaching hospital. In a proteomic analysis of lipid rafts from human T cells, we identified stomatin-like protein (SLP)-2 as a candidate molecule involved in T cell activation through the Ag receptor. MSCs derived from muscle and adipose tissue in ttw mice had a high osteogenic potential. The recent advances in anti-HIV therapy have not seen a clear counterpart in improved antilymphoma therapy, but trials are underway that may help move this field forward. Indeed, we observed a transient upregulation of ephrin-B1 immunoreactivity in hippocampal astrocytes following moderate controlled cortical impact model of TBI.

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Zebra body formation was also confirmed using electron microscopy. Characterization and Immunomodulatory Activity of a Novel Peptide, ECFSTA, from Wheat Germ Globulin. Isotropic microparticles prepared from a suspension that undergoes polymerization have long been used for a variety of applications. Recurrent inflammation leads to destruction of cartilaginous tissues, such as ear, nasal septum, larynx, trachea and bronchi, peripheral joints and vertebral structures. It is possible to reduce this variability by pre-mixing the cement, e.g. The side and location of the primary epileptogenic area of these patients (5 left TLE, 8 right TEL) was determined invasively during presurgical evaluation. A remarkable increase in aerobic power was not observed in trained boys before the age of peak height growth velocity (PHV). In this review we summarize the available data on unusual activities of aaRSs.

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Effects of gastrin-releasing peptide and analogues on guinea prograf 20 mg pig nasal mucosal secretion. Revisiting graft-versus-host disease models of autoimmunity: new insights in immune regulatory processes. Evidence-Based Approach to Treating Lateral Epicondylitis Using the Occupational Adaptation Model. Within each impairment category patients were randomly assigned to one data set to create the system (through recursive partitioning) or a second set for validation. There are various applications of cladistic analysis in the study of complex diseases.

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On the ground, the perception of position and motion is determined by central nervous system integration of concordant and redundant information from multiple sensory channels (somatosensory, vestibular and visual) which collectively yield veridical perceptions. Changes in the chemical composition of Hymenolepis diminuta (Cestoda: Cyclophyllidea) during prepatent development within the rat intestine. To evaluate whether evidence based clinical pathways for acute management of hip fracture have an effect on patient care, short term mortality, or residential status. Two patient survived--one three years, and the other one half a year from the operation. We propose a single superfamily or order with members in several viral families. We report a case of human African trypanosomiasis caused by Trypanosoma brucei rhodesiense. Rate-related changes in QRS morphology in patients with fixed bundle branch block: implications for differential diagnosis of wide QRS complex tachycardia. Also, the case suggests that there may be a locus for oligomeganephronia distal to the Wolf-Hirschhorn critical region on 4p.

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The indication of dabigatran and rivaroxaban for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation, and the indication of rivaroxaban for the treatment of deep-vein thrombosis and for the long-term prevention of venous thromboembolism are based from large, randomized trials. The binding differs in that C-5 is not at a position suitable for hydroxylation. The UPR may offer a possible explanation for how immunosuppressive regimens based on CsA promote renal carcinogenesis. Zebra mussels attached to unionoids had significantly larger shells, higher standardized body mass and glycogen content than those attached to inanimate substrates, suggesting that D. Human ESCs (hESCs), however, closely resemble mouse epiblast stem cells and correspond to the primed state.

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Expression of Terpenoids 1, a glandular trichome-specific transcription factor from tomato that activates the terpene synthase 5 promoter. Findings and outcomes: Following device iterations and occupational therapy sessions, the patient achieved higher functionality in performing daily tasks such as cooking and cleaning, and in completing the Box and Blocks test, though some limitations still precluded lasix tabletas 40 mg para que sirve full acceptance of the device. Both map position and physiological criteria suggest the gibberillin biosynthesis gene dwarf3 as a candidate gene for this QTL. and Prochlorothrix hollandica as to how the thylakoid membrane is organized. HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome represents a life-threatening pregnancy disorder with high fetal and maternal mortality, but its underlying molecular mechanisms remain unknown. The effects of variations in inspiratory: expiratory ratio on cardiorespiratory function during controlled ventilation in normo-, and hypo-and hypervolaemic dogs. In the present study sample, the prevalence of hepatic steatosis was high, particularly in the male patients. However, little is known of how retinal neurons form this laminar-specific synaptic structure during development. Scorpion primers can be used to detect PCR products in homogeneous solution.

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