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Amitar (Amitriptyline)

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Amitar is used to treat depression. Compared to other antidepressants, it has a higher risk of side effects, such as weight gain and drowsiness. Amitar is a tricyclic antidepressant (TCA). It works on parts of the brain responsible for raising levels of certain chemicals, like serotonin and norepinephrine, to help improve your mood.

Other names for this medication:
Amicure, Amidez, Amiline, Amimax, Amitar, Amitop, Amitrac, Amitrim, Amitriptyline, Amitrix, Amitrol, Amitwix, Amiwel, Amize, Amizep, Amoten, Amsha, Amtran, Amypres, Arpidox, Axtrip, Bluneel, Chlotrip, Eliwel, Endep, Estiline, Kamitrin, Latilin, Librodep, Lodep, Maxitrip, Nextrip, Normaline, Psycomer, Raitrip, Ristryl, Sarotena, Tablin, Tadamit, Tryptomec, Zodep

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Also known as: Amitriptyline


Amitar (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitar is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitar dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitar are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitar if you are allergic to Amitar components. Do not take Amitar if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitar if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitar if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitar you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitar if you are going to have a surgery. It can be dangerous to stop Amitar taking suddenly.

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Spleno-enteritis caused by adenovirus in psittacine birds: a pathological study. An information-processing model provided a good description of the quantitative results. The aim of this study was to evaluate whether BNP and RVEDVI are clinically valuable parameters that can distinguish among hypovolemia, euvolemia, and hypervolemia, as measured by blood volume (BV) analysis in critically ill surgical subjects. The objective of this study was to determine what injury control interventions are currently carried out by physicians and to examine how these interventions could be more effective. To study umbilical cord interleukin-6 levels and the occurrence of neonatal sepsis, congenital pneumonia, necrotizing enterocolitis, and grade II-IV intraventricular hemorrhage. Perceived acceptability affects the interpretation of a given risk more than the numerical relevance of the risk. A computer representation of the model permits a simulation of the labeling curves obtained in what kind of drug is plavix pulse and intermittent labeling regimes. Evidence for a pathogenic role of BRCA1 L1705P and W1837X germ-line mutations.

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Clinically relevant doses of R-MO, vehicle dimethyl sulfoxide (DMSO) or saline were administered for three days during the hole-board test and in in vivo DG-LTP. Relationship between the degree of poverty and the IgE response to Ascaris infection in slum children. Role of subtotal thyroidectomy in the management of the follicular neoplasm of the thyroid. Although in vitro and in vivo studies suggest a role for IL-6 in peripheral nerve physiology, this cytokine does not appear to have a substantial effect on functional recovery in a mouse sciatic nerve injury and repair model. Routine HO prophylaxis with NSAIDs should be considered for patients undergoing hip arthroscopy with osteoplasty. In the current study, viable hepatocytes were first identified by flow cytometric assessment of fluorescein diacetate staining. Nonmediated, Label-Free Based Detection of Cardiovascular Biomarker in a Biological Sample. Physiological roles of glucocorticoids during early embryonic development of the zebrafish (Danio rerio). Unlabeled LPS decreased FITC-LPS binding in both fasciculata-reticularis and glomerulosa cells, suggesting competition of both ligands for a limited number of binding sites.

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