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Amitone (Amitriptyline)

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Amitone is used to treat depression. It is more popular than comparable drugs. Amitone is only available as a generic drug; all brands have been discontinued. Amitone is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower.

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Also known as: Amitriptyline


Amitone (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitone is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitone dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitone are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline.

Avoid driving or hazardous activity until you know how Amitone will affect you. Your reactions could be impaired.

Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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The NRS has strong psychometric properties in adults, and a pediatric version is under development. The main clinical symptoms including abdominal pain and lower back pain were alleviated, and the mean visual analog scale (VAS) pain score declined from 5.1 points to just 3.3 points immediately after the HIFU treatment. Differences in survival rates were compared using the log-rank test. Hemolytic-uremic syndrome in pneumococcal meningitis and infection. Chronically mentally ill patients with and without substance use disorders: a pilot study. Initial evaluation of the MDHI provides evidence that it is valid and reliable as an outcome measure for assessing patient-reported health. To determine the effects of fat emboli on cardiopulmonary function in critically ill patients.

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When compared to clinicopathologic variables, GC better predicted metastatic progression among this cohort of men with BCR following RP. The ability to study health-related behaviors in combination rather than singly will lead to a more comprehensive approach to health promotion. Severity and chronicity of depression are associated with a higher mortality risk. Sequence analysis and homology searches identified three known genes related to growth control, lipid and connective tissue metabolism. Moreover, patients admitted with non-respiratory symptoms had significantly lower levels of serum cotinine (mean of 3.9 ng/ ml) than both phases of patients with RSV bronchiolitis. Imatinib mesylate treatment decreases fibrosis and results in the relatively rapid and steady improvement of skin changes and knee joint contractures in patients with stage 5 chronic kidney disease and NSF, despite the persistence of gadolinium in the tissues. However, for the mass balances between both models, some hypotheses were considered and might be evaluated.

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Optimized lens-sparing treatment of retinoblastoma with electron beams. Sevoflurane preconditioning increased levels of TREK-1 mRNA and protein. Chronic hypotension, although unfrequent in uremic patients on hemodialysis, accentuates the deterioration of patients physical state and thus, their general well-being. A comparison of ventilatory prostate movement in four treatment positions. AlloP administration did not affect passive avoidance retention, and also showed a non anxiolytic-like profile, possibly related to fluctuations of endogenous AlloP concentrations induced by the stress generated by the high foot-shock punishment received before the anxiety tests. NPS misusers require specific assessment and risk management to reduce the risk of violence towards others. We discuss here the pathogenic potential of TcpC and its interaction with TLRs and TLR-adapter proteins on the molecular level and compare its activity with the activity of other bacterial TIR-containing proteins. The predictive performance of the constructed model indicates potential clinical utility for the identification of patients at risk of hypoglycaemia during their inpatient stay.

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The goal of the present work was to study the protective activity of strains of T. Preventive and therapeutic vaccines against Helicobacter pylori: current status and future challenges. Quick diagnosis units (QDUs) are a promising alternative to conventional hospitalization for the diagnosis of suspected serious diseases, most commonly cancer and severe anemia. Small clinical trials, in particular, provide a major problem not only by themselves, but also if they become incorporated in systematic reviews without appropriate consideration of the phenomenon of publication bias. The cDNA alfuzosin uroxatral drug class library was screened with a radioactively labeled CAR1 cDNA probe, and clones that hybridized with the probe were isolated. We investigated the clinical and virological characteristics of three patients who developed a mesangial proliferative and sclerosing glomerulopathy alone or in association with membranoproliferative glomerulonephritis after liver transplantation for end-stage liver disease secondary to HCV infection. In this study we try to test the hypothesis that the intensity of depression in an early stage (4th week) of cerebral vascular accidents (CVA) in related to lesion location and type of lesion.

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Effective saline douching may improve long-term outcomes of chronic rhinosinusitis but is often impaired by postoperative ostial stenosis. Clinical evaluation of formalinized horse red cell agglutination test. This finding might result from primitive stream segregation or schema-driven selection, but not from peripheral channeling. Prospective comparative trial of endovaginal sonographic bimanual examination versus traditional digital bimanual examination in nonpregnant women with lower abdominal pain with regard to body mass index classification. Others may be managed successfully with posterior cranial vault distraction, middle vault expansion, or fronto-orbital advancement. Serum ferritin levels were lower in 10 of 13 patients studied after 24 h of vitamin B12 therapy and in all 13 studied at 48 h after therapy.

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