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Amotrex (Metronidazole)

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Amotrex belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
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Also known as: Metronidazole


Amotrex (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

Amotrex is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use Amotrex to treat any condition that has not been checked by your doctor.


Amotrex 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Amotrex and 250 on the other side; bottles of 50, 100, and 2,500. Amotrex 500-mg tablets are oblong, blue, film coated, with Amotrex debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


Single oral doses of Amotrex, up to 15 g, have been reported in suicide attempts and accidental overdoses. Symptoms reported include nausea, vomiting, and ataxia. Oral Amotrex has been studied as a radiation sensitizer in the treatment of malignant tumors. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 to 10.4 g every other day.

There is no specific antidote for Amotrex overdose; therefore, management of the patient should consist of symptomatic and supportive therapy.


Store Amotrex at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Amotrex out of the reach of children and away from pets.

Side effects

The most common side effects associated with Amotrex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of metronidazole capsules and tablets in the pediatric population, except for the treatment of amebiasis. Safety and efficacy have not been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of metronidazole extended-release tablets to treat bacterial vaginosis in teenage females, but should not be used before the start of menstruation.

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Effects of benzoquinone and naphthoquinone derivatives on the incorporation of acetate-1-14C into cholesterol in rat liver homogenates. Simultaneously the data of wind direction, wind speed, atmospheric rel. Structural equations to model relationships between pulmonary function, fatty acids and oxidation in cystic fibrosis. The probes are based on a self-immolative linker, which allows positioning both dyes in close spatial proximity to ensure efficient quenching of probes with absorption and fluorescence emission in the near-infrared (NIR) range. Sertoli-Leydig cell tumors are rare sex-cord stromal tumors of the ovary that can present with a variety of histological elements, which may complicate diagnosis and treatment. The present investigation was performed to assess the significance of prenatal Doppler findings relative to postnatal anthropometrics and body composition in IUGR newborns over the first 12 months of life.

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Most of our knowledge of hematopoietic stem cells is from animal models in which purified stem cell canididates are assayed based on their functional ability to rescue lethally conditioned recipients. Mutation in the caveolin-3 gene causes asymmetrical distal myopathy. The study of hepatic fibrosis, or scarring in response to chronic liver injury, has witnessed tremendous progress in the past two decades. Our findings indicate that the two SmgGDS isoforms differ in GTPase binding and GEF activity, depending on the lipidation state, thus providing useful information about the cellular functions of SmgGDS in cells. Stimulus intensity control and the cortical evoked response in smokers and non-smokers. In general, many of these studies have been underpowered or have not been extensive enough in investigating the full extent of genetic variation in these genes. Association between cotinine-verified smoking status and hypertension in 167,868 Korean adults. Although a simultaneous increase of diffusion-weighted MR signals was observed together with the prolonged depolarization of neurons induced by pharmacological manipulations (in which cell swelling was demonstrated to play an important role), no evidence was found that diffusion MR signals directly correlate with normal spontaneous neuronal activity.

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Changes in thoracopulmonary compliance and hemodynamic effects of positive end-expiratory pressure in patients with or without heart failure. The use of icodextrin, Interceed (Ethicon Inc, Somerville, New Jersey, USA) and Oxiplex seem to be justified by the currently available data. Clinical consequences of SCI are due to a series of secondary injury cascades. Although viscoelastic Voigt modeling of the QCM-D data suggests a comparable layer thickness for the copolymers on the silica surface, the AFM imaging and colloidal probe measurements reveal significant differences in surface coverage and thickness of the layers, which are discussed and compared with respect to the stabilization effect by the hydrophilic poly(ethylene glycol) block. The authors review the case-history of a 67-year old female patient suffering from papillomatosis cutis carcinoids.

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Nursing case management for children undergoing craniofacial reconstruction. Long-lived photoinduced charge separation for solar cell applications in supramolecular complexes of multi-metalloporphyrins and fullerenes. Using locoregional anesthesia and sedation for dacryocystorhinostomy is safe and effective and provides a valid alternative to general anesthesia. Given the wide scope of these concerns, it is not possible to discuss any issue in detail, and the paper does not claim to give the subject matter a comprehensive or global treatment. Confocal fluorescence analysis of the depth and focus of cytogenetic preparations. Hirschsprung disease (HD), or congenital aganglionosis coli, is a birth defect with heterogeneous causes. Thyroid scintiscans in children and adolescents with chronic lymphocytic thyroiditis. The transitions of the viscosity profiles correlated well with the major structure transitions at a protein concentration of 150 mg/mL. A decrease in a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs-13 (ADAMTS-13) that cleave UL-vWFMs might cause excessive UL-vWFMs activity and result in platelet thrombus formation.

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Baculovirus-mediated expression and characterization of the full-length murine DNA methyltransferase. Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Post-eruptive maturation seems to be present not only in permanent teeth but also in primary molars. Pubmed, Embase and Cochrane databases were searched through June 2016 for cohort studies reporting outcomes of SRS or WBRT after metastasis resection. The rate of perioperative mortality was significantly increased in cases of embolic and hemorrhagic complications, as well as in cases of failure and underlying intracranial stenoses. Protein microarrays provide a high-throughput platform that enables the profiling of serum antibodies to a large number of protein antigens. Significantly larger amounts of posterior corneal aberrations and stronger compensation effects were observed in KC eyes can u drink alcohol on levaquin than in normal eyes.

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Laparoscopic cholecystectomy under spinal anaesthesia: a prospective study. Side effects of the surgery mainly included foreign body response, transient elevated intraocular pressure, cataract formation/deterioration and posterior capsule opacity. The described technique is effective for detailed morphological analysis of stem cell spheroids, organoids, as well as organotypic cell cultures. Intracellular and extracellular edema of moderate severity was slightly worse in the subendocardium, and reversible mitochondrial injury of a mild to moderate degreee was symmetrically present. Mechanism of blood pressure reduction by teprotide (SQ 20881) in rats. The nonculturable state in pathogenic bacteria modelled on Salmonella typhimurium: the phenomenon and its genetic control. Negative urgency and ventromedial prefrontal cortex responses to alcohol cues: FMRI evidence of emotion-based impulsivity. There was a marked increase in the concentration of fatty acids in the blood with monounsaturation in both carbon-16 and carbon-18 chains and diunsaturation in the later carbon chains. The model is tested independently and its skill assessed using two skill measures. This replication activity is consistent with a reverse transcription model for CaMV replication based on results which demonstrate that incorporation of deoxyribonucleotides into minus-strand DNA is refractory to actinomycin D while incorporation into plus-strand DNA is inhibited by the drug.

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Investigations using a non-human primate model of increasing durations of cocaine exposure revealed that initially the effects of cocaine were restricted to ventromedial and orbital prefrontal cortices, but as exposure was extended the intensity and spatial extent of the effects on functional activity also expanded rostrally and laterally. The objective of the present study is to evaluate the cytotoxicity, in vivo degradation and drug release of PEG-g-CS hydrogel. Golgi dying, double immunofluorescence method and RT-PCR were used to detect dendritic spine density, expression patterns of ephrin-A5 and the effect of EA on them at the end of the first, second and fourth week after ischemia. Therefore, we propose that Eagle syndrome results from a protective response to increased tensile stress in the ligament attached to the styloid process, which could also signal osteogenetic protein expression in the periosteal fibrous tissue. Six horses that developed acute airway obstruction (heaves) when what is the prescription dosage of pepcid housed in a barn and fed poor-quality hay were studied. Intravenous melphalan and dexamethasone followed by lymphoblastoid alpha interferon in higher risk multiple myeloma patients. This suggests that the characteristic smooth muscle cell loss observed in BAV aortopathy may be a consequence of superoxide-mediated cell damage. As telehealth plays an even greater role in global health care delivery, it will be increasingly important to develop a strong evidence base of successful, innovative telehealth solutions that can lead to scalable and sustainable telehealth programs. Impacted calculi were located in bilateral ureters in 22 patients and unilateral ureters in 5 patients with a solitary or single functioning kidney. One limitation of traditional PCR-based methods is that they are normally limited to the analysis of a single pathogen, a small group of related pathogens, or a small number of relevant genes.

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Multiple chronic stressful factors, both previous SSD and those over time, have commonly an impact on the mental health of patients with SSD. A sensitive and specific determination of gamma aminobutric acid in brain. Contraceptive steroids (particularly ethinyl estradiol) are therefore rarely used. Structures of the lectin IV of Griffonia simplicifolia and its complex with the Lewis b human blood group determinant at 2.0 A resolution. However, there has been an increasing evidence that suggest NAFLD to be an independent risk factor of CVD. Accordingly, just as was found for the hind limb nerves, the position of the somata of the sensory neurons of forelimb nerves can be restricted to the rostral or caudal half of a DRG. It is hoped that future research will further clarify which treatments are useful in which children. Validation of Stroke Meaningful Use Measures in a National Electronic Health Record System. Initially, a 14- item summated rating scale was developed with inputs from five dermatologists and a clinical pharmacologist. The decrease in CD59 expression induced by high glucose concentrations was reversed by coincubation of cells with a calcium channel blocking agent (Verapamil).

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Sick-leave decisions for patients with severe subjective health complaints presenting in primary care: a cross-sectional study in Norway, Sweden, and Denmark. The IBDV antigens in bursa tissue samples from six poultry farms were detected by both probes. These were: immunity/infection/asthma, cardio-metabolic, neurodevelopmental/attention, thyroid, renal, and puberty onset. Medical treatment with antiestrogen noroxin 400 mg plm therapy has shown promising results, but further research is needed to determine the long-term side effects and the limitations of lifelong therapy. More efficient stimulation for patients with borderline cardiac resynchronisation therapy indication?. The gene encoding ropp120 (HGMW-approved gene symbol C2orf2) was assigned to chromosome 2p21-p22 by means of radiation hybrid and fluorescence in situ hybridization mapping.

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Development of bacteria and their activity in an aqueous surface film under experimental conditions. Patients seeking treatment at the Addiction Research Foundation for a substance problem but who also reported psychiatric symptomatology were referred to the Mental Health Unit. These results show that RAGE and PI3K modulate adhesion and migration rate of neutrophils on AGE-collagen. This muscular unbalance can explain the abnormal motion of the patella. A threshold method to improve standardized uptake value reproducibility. Examination revealed a fistulous tract between vestibule of the vagina and an otherwise normally formed anal canal. support of the clinical diagnosis of dementia of the Alzheimer type, presurgical ictal detection of seizure focus, detection of acute ischemia and differential diagnosis between radiation necrosis and brain tumor recurrence.

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