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Cotrip (Amitriptyline)

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Cotrip works by affecting the balance of certain chemicals in the brain. It helps improve mood, relieve anxiety and tension, helps you sleep better, and increase your energy level. Cotrip is readily absorbed and starts action within approximately 6 hours of taking it orally.

Other names for this medication:
Amicure, Amiline, Amitar, Amitin, Amitop, Amitrac, Amitrim, Amitrip, Amitryn, Amitryptyline, Amity, Amiwel, Amize, Amizep, Amsha, Amtipax, Amypres, Axtrip, Cotrip, Crypton, Kamitrin, Latiln, Libotryp, Libral, Mitrip, Mitryp, Normaline, Raitrip, Ristryl, Sereval, Tadamit, Tridep, Tryptomec, Typlin

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Also known as: Amitriptyline


Cotrip target is the treatment of depression. Cotrip is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Cotrip is Amitriptyline. Cotrip is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Cotrip are Cotrip, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Cotrip dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include irregular heart rhythm, feeling like you might pass out, seizures, or coma.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Cotrip are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with amitriptyline.

Avoid driving or hazardous activity until you know how Cotrip will affect you. Your reactions could be impaired.

Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

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Production of matrix metalloproteinase 9 (92-kDa gelatinase) by human oesophageal squamous cell carcinoma in response to epidermal growth factor. An early category-specific neural response for the perception of both places and faces. Erysipelas are common soft tissue infections responding to first-line antibiosis. Use of work-life balance benefits guaranteed by law in Poland - Do size of the enterprise and gender matter?. High mobility group non-histone chromosomal proteins from chicken erythrocytes. To date, however, there have been few studies of the impact of nocturnal awakening from asthma on children with the disease, including problems with daytime functioning. With insulin-like growth factor, however, TGF-beta potentiated the ex vivo recovery of IL-1 induced suppression of proteoglycan synthesis. Permeability to macromolecules is diminished in a hamster cheek-pouch model. Monoclonal antibody (MAb) 3C9, an antibody generated to the lamellar body of rat lung type II pneumocytes, specifically labels the luminal face of the lamellar body membrane. The binding was probably non-covalent and reached saturation within 5 min.

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Here we used the pro- and anti-saccade task to examine the relative contribution of reflexive and voluntary eye-movement control in profoundly deaf and hearing individuals. Postoperatively, hypoperfused areas in SPECT were improved (Fig. Bilateral Large Pneumothoraxes Following Implantable Cardioverter-Defibrillator Generator Change: A Case Report of an Uncommon Event Complicating a Common Procedure. MTT is trazodone a strong sleeping pill colorimetry, colony-forming unit counting method, and scanning electron microscopy were used to measure bacterial adhesion. Protein-tyrosine phosphatases (PTPs) are key regulators of the insulin receptor signal transduction pathway.

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Comparative characteristics of status asthmaticus and severe attacks of bronchial asthma. However, there is no effect of the alkaloids on cellular oxygen consumption. Distinct Blood and Visceral Adipose Tissue Regulatory T Cell and Innate Lymphocyte Profiles Characterize Obesity and Colorectal Cancer. The two major subtypes of glycine transporters, GlyT1 and GlyT2, have been linked to the pathogenesis and/or treatment of central and peripheral nervous system disorders, including schizophrenia and related affective and cognitive disturbances, alcohol dependence, pain, epilepsy, breathing disorders and startle disease (also known as hyperekplexia). Based on denaturation efficiency, minimum renaturation tendency, and fragmentation, the sonication method was found to be the best among the six methods.

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Right atrial thrombus from inferior vena cava after acute cardiotoxicity of 5-fluorouracil. A computer controlled water phantom dosimetric system is used to generate profile data for physical wedges, whereas a 0.6 cm3 ion chamber is used for generation of profiles for dynamic wedge and wedge factors for both types of wedges. Imprinting is a classic mammalian epigenetic phenomenon that results in expression from a single parental allele. Infrared thermography is a non-invasive technique that measures mid to long-wave infrared radiation emanating from all objects and converts this to temperature. A method for simply and accurately locating the umbilicus in abdominoplasty is described. Increased ascorbic acid level in the aqueous humour after administration of ACTH. Diagnostic modalities, especially different sites of biopsy or needle aspiration are discussed.

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In order to physically cover the Tm-2a region, R12 and the flanking DNA marker TG207 were used to select homologous YAC clones. The data further suggest that the underlying mode of gene action is complex and cannot be can i give my toddler cough medicine and motrin explained by simple additive or additive-dominance models. The apoptotic index reached the control value within 1 month after eradication in CNAHG patients but remained relatively high in CAHG patients. The larval electric organ of Pollimyrus isidori consists of four longitudinal tubes, a dorsal and a ventral pair, which begin behind the skull, end at the beginning of the caudal peduncle and show myotomic segmentation. A novel test of planning ability: great apes can plan step-by-step but not in advance of action. Furthermore, HSV-2 infection of DCs required endocytosis of viral particles and their delivery into an acid endosomal compartment. Three 1-2-cm intercostal ports in the right chest were used for access in the endoscopic group. The present review examined the published data available for AKI in patients undergoing peripheral procedures using MEDLINE searches.

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The place of chemotherapy with 5 per cent 5-fluorouracil ointment in the treatment of malignant disease of the skin. To examine the personal characteristics of six consecutive rural longitudinal integrated clerkship student cohorts to understand whom the programs attract and select and thus inform the development of such programs. 45 cases of a dermatosis believed to be the same as those originally described by Schrank in 1963 among Nigerian children of Yoruba ethnic origin and named keratosis circumscripta by him are reviewed. This is a common behaviour from which it has been possible to delineate a general method for the easy assignment of the peaks in PSD spectra of underivatized neutral sugars, allowing the sequence of a real unknown to be obtained. Succinic acid infusions for correction of renal ischemia in patients with acute purulent pyelonephritis. The single laboratory tests were of limited value in predicting appendicitis. New efforts and resources should be transferred to clinical research for the complete evaluation of the therapeutic potential of FA in chronic diseases. However, information on optimal treatment regimens for these patients is limited. It has been possible to probe the role of GLP-1 for the diabetes resolution after gastric bypass using a GLP-1 receptor antagonist, and it is clear that the enhanced beta cell sensitivity to glucose which underlies the enhanced insulin secretion in the patients after the operation depends critically on the increased GLP-1 secretion.

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Phenotypic extremes of BICD2-opathies: from lethal, congenital muscular atrophy with arthrogryposis to asymptomatic with subclinical features. Social skills group training (SSGT) for children and adolescents with autism spectrum disorder (ASD) is widely applied, but effectiveness in real-world practice has not yet been properly evaluated. The focus groups conducted with fibromyalgia patients identified symptom domains that had the greatest impact on their quality of life including pain, sleep disturbance, fatigue, depression, anxiety, and cognitive impairment. General practitioners will have local contracts reflecting their desire to provide an expanded range of services and the needs of the community. The author has given bromperidol to a first group of fifteen patients with a clear psychotic condition, mostly of the schizophrenic type. Possible clinical correlation with amelioration of paraphilia is discussed. A negative correlation between miR-20a and its target genes is observed in breast cancer tissues. A larger study involving both spot and broadcast application and including direct observation of pesticide application is needed to ascertain whether pesticide application on athletic fields results in measurable and potentially hazardous exposure of children. Thyroglobulin polymorphisms in Tunisian patients with autoimmune thyroid diseases (AITD). New Soviet miotic preparation benzamon and its therapeutic significance in glaucoma.

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