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Epivir (Lamivudine)
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Epivir

Epivir is used to treat hepatitis B infection. Epivir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.

Other names for this medication:
Abamune, Combivir, Duovir, Emduo, Emtri, Haptavir, Hepavud, Hepitec, Hepravir, Hivir, Ladiwin, Lamidac, Lamistar, Lamivir, Lamivox, Lamivudine, Lamostad, Lamuvid, Lavir, Lazid, Lmivir, Nevilast, Odivir, Retrolam, Shanvudin, Stadin, Stavex, Tenola, Tenolam, Tenvir, Trimune, Trioday, Viramid, Virolam, Virolis, Zidolam

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Also known as: Lamivudine

Description

Epivir (lamivudine) is an antiviral medicine that prevents human immunodeficiency virus (HIV) or hepatitis B virus from multiplying in your body.

Epivir is for treating HIV in adults and children at least 3 months old. HIV is the virus that can cause acquired immunodeficiency syndrome (AIDS). Lamivudine is not a cure for HIV or AIDS.

Epivir-HBV is for treating hepatitis B in adults and children at least 2 years old. It should not be used in people who are infected with both hepatitis B and HIV.

Dosage

Take Epivir exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. You should not take Epivir (for treating HIV) together with Epivir-HBV (for treating hepatitis B).

You may take this medicine with or without food.

Lamivudine doses are based on weight in children. Your child's dose needs may change if the child gains or loses weight. Children who weigh more than 30 pounds (14 kilograms) should use the tablet form if possible. The liquid form may not be as effective.

You may need to break a tablet in half when giving this medicine to a child for HIV. Call your doctor if the child has any trouble swallowing the tablet.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

The Epivir brand contains a higher dose of lamivudine than Epivir-HBV brand. Epivir is for treating HIV and Epivir-HBV is for treating hepatitis B. Each time you get a refill of this medication, be sure you have received the correct brand to treat your condition.

You will need frequent medical tests, including frequent HIV testing. If you become infected with HIV while you are taking lamivudine to treat hepatitis B, the HIV could become resistant to antiviral medicines if not treated right away.

The hepatitis B virus can mutate while you are taking Epivir-HBV and may become resistant to treatment. Resistant hepatitis B can lead to worsening liver disease or death. Tell your doctor if you have new or worsening hepatitis symptoms.

Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor's advice. Every person with HIV should remain under the care of a doctor.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

If you've ever had hepatitis B, this virus may become active or get worse in the months after you stop using Epivir. You may need frequent liver function tests while using this medicine and for several months after your last dose.

Detailed Epivir dosage information

Overdose

If you overdose Epivir and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Epivir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Epivir HBV if you are allergic to it.

You should not take Epivir-HBV (for treating hepatitis B) if you also take other medicine that contains Epivir HBV or emtricitabine, which includes Atripla, Biktarvy, Cimduo, Combivir, Complera, Descovy, Emtriva, Epzicom, Genvoya, Odefsey, Stribild, Symfi, Triumeq, Trizivir, and Truvada.

Tell your doctor if you have ever had:

liver disease (especially hepatitis B or C, or a liver transplant); pancreatitis; kidney disease; or diabetes (liquid Epivir HBV contains 3 to 4 grams of sucrose per dose).

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, if you've taken HIV medication for a long time, or if you are a woman. Ask your doctor about your risk.

Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.

You should not breastfeed while you are using Epivir HBV to treat hepatitis B. Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

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