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Klonopin (Clonazepam)

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Klonopin is one of the products that belong to the bensodiazepine group and have a strong sedative effect. Klonopin helps to stop convulsions and epileptic seizures. It is widely used among people with severe panic attacks and anxiety caused by depression treatment.

Other names for this medication:
Adnil, Alrest, Anxrea, Clonapax, Clonark, Clonasig, Clonatrac, Clonazepam, Clonoasig, Clonotril, Clonzy, Clopam, Clotas, Clozep, Clozipam, Convaclon, Dipwell, Easyfeel, Epicloz, Epitril, Escimax, Escitacalm, Estalonix, Jasoclam, Jbcloz, Lonazep, Lonipax, Lozep, Nazee, Prasilex, Rivotril, Sezolep, Somnolex, Somnotril, Ubitpam, Xitzen, Zeficar, Zepam, Zepamax, Zeptril, Zicam

Similar Products:
Priligy, Xanax, Ceftin, Allegra, Trandate, Asacol, Divisone, Cerinorm, Fegra, Indikof, Desval, Exfen,

Also known as: Clonazepam


Klonopin is a benzodiazepine medication that was initially primarily used for the treatment of seizures occurring in epilepsy and for anxiety, specifically anxiety that occurs in panic disorder. Klonopin is available in tablet form (0.5 mg, 1 mg, 2 mg) and as disintegrating wafers that are taken orally.

While Klonopin is generally prescribed for the treatment of anxiety disorders, such as panic disorder, and seizure control, it is intended as a short-term treatment protocol as opposed to a long-term treatment solution due to issues with tolerance (see below). In addition to treating anxiety and seizures, Klonopin has also been used in the treatment of:

chizophrenia, especially when the individual with schizophrenia has a restless or irritable component and is not responding to antipsychotic medications.

The manic phase of bipolar disorder or for restlessness associated with depression in bipolar disorder.

Tic disorders, such as Tourette's syndrome, by acting as a muscle relaxant and producing sedation.

Restless leg syndrome.

Withdrawal from alcohol or treatment for other substance abuse or addiction issues.

Klonopin has a relatively slow onset of action (it takes a while for the drug to begin working) and a half-life of between 10 and 50 hours. As it has a relatively slow onset of action and is a longer-acting benzodiazepine, Klonopin is more suited for the treatment of anxiety, seizures, and other similar disorders as opposed to being a useful sleep aid, even though it is sometimes prescribed for that purpose. Sleep aids need to work quickly, whereas with Klonopin, a person takes the drug early in the day and doesn't have to worry about monitoring for signs of a seizure or panic attack as it stays in the system a relatively long time. Its effects last longer than those of shorter-acting benzodiazepines, such as Xanax.

As it is a Schedule IV controlled substance, Klonopin can only be legally acquired with a prescription from a physician.


Klonopin is also used to treat symptoms of akathisia (restlessness and a need for constant movement) that may occur as a side effect of treatment with antipsychotic medications (medications for mental illness) and to treat acute catatonic reactions (state in which a person does not move or speak at all or moves or speaks abnormally). Talk to your doctor about the possible risks of using this medication for your condition.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to Klonopin.

Do not let anyone else take your medication. Klonopin is a controlled substance. Prescriptions may be refilled only a limited number of times; ask your pharmacist if you have any questions.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.


Benzodiazepines like Klonopin became popular prescription medications, as alternatives to another class of anti-anxiety medications called barbiturates. Barbiturates were once very popular in the treatment of anxiety; however, they were highly addictive, carried a high risk for overdose, and were frequently abused. Benzodiazepines also carry a significant risk for the development of physical dependence and abuse (see below); however, they do not appear to carry the same risk of overdose that is associated with barbiturates (although overdose on benzodiazepines can occur).

Many of the cases of overdose that include benzodiazepines also include the co-occurring use of other drugs, such as alcohol, narcotic pain medications, or antidepressants. Using these drugs and benzodiazepines like Klonopin together enhances the effects of all drugs as well as increases the risk for overdose and potential fatalities due to drug interactions and drug overdose.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Klonopin Wafer dosage information

Side effects

The most common side effects associated with Klonopin are:

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6-Mercaptopurine treatment of pregnant mice: effects on second and third generations. The human L23 (mitochondrial)-related protein gene, located 40 kb downstream of the imprinted H19 gene, is biallelically expressed. Effectiveness of calcium lactate added to food in reducing intraoral demineralization of enamel. The sacral DAVF was treated surgically, and the symptoms gradually resolved within 6 months after surgery. The internal carotid arteries (ICAs) were occluded by acute thrombus. Radiographic studies revealed coxa valga and acro-osteolysis of the terminal phalanges. We prove that the value of the span is always smaller (and can be much smaller) than the diameter of the smallest sphere containing the support vectors, used in previous bounds (Vapnik, 1998). The present data give further support to the role of the endothelin signaling pathway in the development of neural crest-derived enteric neurons. However, ischemic damage and follicular loss during the in-vitro culture of OCTs are major technical challenges. White Paper: Interventional MRI: Current Status and Potential for Development Considering Economic Perspectives, Part 1: General Application.

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The complexity of the procedure, the several techniques used and the diversity of the patients hinder the reproduction of the results and the indication for the procedure. The NW PCI model supports the goals of the developing CTSA Trial Innovation Network by increasing access to cutting-edge research across the Northwestern U.S., by supporting investigators seeking diverse populations, including those with rare diseases, for their research studies, and by providing settings to test implementation and dissemination of effective interventions. Maternal uniparental disomy 7 and Silver-Russell syndrome - clinical update and comparison with other subgroups. This syndrome is generally assumed to be inherited in an X-linked dominant fashion with lethality in males. Synthesis, spectral studies, in vitro and in vivo antitumour activity. The abnormal development of the inner ear of the homozygotic kreisler mouse was studied. A disease-based registry was created to collect information for CQI incorporating real-time outcome reporting, patient reported outcomes, stakeholder engagement, and collaborative learning methods to form a comprehensive quality improvement effort. A reliable extended-IADL scale was constructed meeting item response theory assumptions relating to unidimensionality, monotonicity, and invariant item ordering. Bovine enzootic haematuria was diagnosed in Queensland in coastal areas in association with bracken fern (Pteridium esculentum) on 3 properties or with mulga fern or rock fern (Cheilanthes sieberi) on 4 properties, and in inland areas in association with C.

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A total of 1200 girls aged 15-18 years who were trained as confectioners and a control matched group of schoolgirls were examined for their health. A 56-year-old patient with syncope due to carotid sinus hypersensitivity is presented. Birds were trained on a delayed matching-to-sample (DMS) task under either common outcome or differential outcome conditions, and then presented with visual interference during the delay period. The purpose of this paper is to describe and evaluate theoretical principles, possibilities and limits of the qualitative research method called phenomenography. Comparative analysis of the antibodies against capsular polysaccharides of Escherichia coli K-92 and K-235: an immunochemical method for the identification of polysialic acids. The major clinical management problem is that the pathologic process in the brain is usually well-advanced before the patient presents, and the symptoms, particularly in newborns or infants, are often initially nonspecific. The onset of X inactivation is preceded by a marked increase in the level of Xist RNA. Deregulation of the arginine deiminase (arc) operon in penicillin-tolerant mutants of Streptococcus gordonii.

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Buprenorphine augmentation improved symptoms of OCD, compared to placebo - Results from a randomized, double-blind and placebo-controlled clinical trial. Other caveolin-interacting enzymes, including endothelial nitric-oxide synthase and the c-Src tyrosine kinase, are also potently inhibited by each of the four caveolin peptides. Potentiometric and optical polyion probes based on photo-cross-linked thin films of decyl methacrylate (DMA) are described, and the effects of film composition on the response toward heparin are examined in detail. The phylogenetic tree analysis revealed that the porcine ASPA, NAGA, and HEXA all have closer genetic relationships with the ASPA, NAGA, and HEXA of cattle. Also, luteolin is an effective inhibitor of CYP2B6, CYP2C9 and CYP2D6. Measuring personality functioning in older adults: construct amaryl 4 mg tablet validity of the Severity Indices of Personality Functioning - Short Form (SIPP-SF). Synthesis of chiral bisphosphines with tunable bite angles and their applications in asymmetric hydrogenation of beta-ketoesters.

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The handful of cases thus far suggest that regression of these seemingly benign lesions may or may not be associated with dose reduction or discontinuation of heparin products and typically occur within a few weeks. To review the studies conducted on the effectiveness of OME-based treatments applied to children with speech disorders and the theoretical arguments that could justify, or vantin dosing not, their usefulness. This chapter will relate the history of CA inhibitor use at high altitude, discuss what tissues and organs containing carbonic anhydrase play a role in adaptation and maladaptation to high altitude, explore the role of the enzyme and its inhibition at those sites for the prevention and/or treatment of the four major forms of illness at high altitude. The quality questionnaire and SII showed few differences between conditions. There is an increasing number of studies showing that patients often do not receive necessary care or receive care that is not needed, inefficient or even damaging. Research on sleep in depression has provided several valuable biomarkers that are related to increased risk for depression, show worsening during depressive episode, and are related to treatment outcome and relapse risk during remission phase.

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Chemoprevention of glandular stomach carcinogenesis through duodenogastric reflux in rats by a COX-2 inhibitor. A genome-wide association analysis for susceptibility of pigs to enterotoxigenic Escherichia coli F41. In a select group of young and tumor-free patients, additional vaginal reconstruction may be indicated. Influence of treadmill training on bone structure under osteometabolic alteration in rats subjected to high-fat diet. The positive associations with atrophy and intestinal metaplasia have implications for models of gastric carcinogenesis. Headache and visual impairment are the most common symptoms for sphenoid sinus mucocele. Furthermore, we show that NeuN is frequently expressed in NSCLC and provide evidence suggesting that Oct4 cells give rise to cancer cells expressing nestin and/or NeuN. There is evidence that simple excision alone will control seizures in some patients, whereas others require, in addition, seizure surgery with resection of epileptogenic cortex. Robot-assisted laparoscopic surgery in gynecology: scientific dream or reality?.

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