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Lodine (Etodolac)

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Lodine is a prescription medicine used to treat the symptoms of mild-to-moderate pain and inflammation associated with arthritis. Lodine may be used alone or with other medications. Lodine belongs to a class of drugs called nonsteroidal anti-inflammatory drug(NSAID).

Other names for this medication:
Etios, Etobest, Etodolac, Etofree, Etogesic, Etomax, Etoron, Etosafe, Etova, Etura, Freeup, Penalgon, Proxym, Setolac, Toldin

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Artane, Evista, Xanax, Famvir, Lamictal, Zyrtec, Provigil, Xenical, Cialis, Loracyp, Concor, Fenohexal, Alvect, Jydival, Zydena, Momate, Lypin,

Also known as: Etodolac


Lodine (etodolac) is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Lodine is used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis.


This section provides information on the proper use of a number of products that contain etodolac. It may not be specific to Lodine XL. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute pain: For oral dosage form (capsules or tablets): Adults—200 to 400 milligrams (mg) every 6 to 8 hours. However, the dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

For osteoarthritis and rheumatoid arthritis: For oral dosage form (capsules or tablets): Adults—300 milligrams (mg) 2 to 3 times a day, or 400 or 500 mg 2 times a day. Your doctor may lower your dose to 600 mg once a day. The dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—400 to 1000 milligrams (mg) once a day. Children 6 to 16 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, stomach pain, or stomach bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Lodine XL dosage information

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The most common side effects associated with Lodine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Lodine can increase your risk of fatal heart attack or stroke, even if you don't have any risk factors. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Lodine may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using this medicine, especially in older adults.

You should not use Lodine if you are allergic to etodolac, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.

To make sure Lodine is safe for you, tell your doctor if you have ever had:

heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke; a heart attack, stroke, or blood clot; stomach ulcers or bleeding; asthma; fluid retention; liver or kidney disease; or if you take aspirin to prevent heart attack or stroke.

If you are pregnant, you should not take Lodine unless your doctor tells you to. Taking a NSAID during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.

Lodine is not approved for use by anyone younger than 18 years old.

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Decreased CD44H expression in early-stage tongue carcinoma associates with late nodal metastases following interstitial brachytherapy. Acute care hospitals have and continue to be the predominant employer of RNs. The delayed hyperpolarization could not be reversed by passing hyperpolarizing current, but actually increased in size with higher membrane potentials. The instrument developed uses a green-emitting helium-neon laser as the light source, a piezoelectric movable beamsplitter to generate two mutually coherent laser beams of variable relative phase and two single-mode fibres to transmit these beams to the microscope. We found that for general purposes, the susceptibility test selected for AMR surveillance must be carefully chosen considering the purpose of the surveillance since the ability to detect resistance appears to vary between these tests depending upon the population where they are applied.

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Cystinosis distal myopathy, novel clinical, pathological and genetic features. The cost savings that resulted from bid purchasing of drugs by one hospital using an ABC analysis is also described. Genetically determined electrophoretic variants of human red cell NADH diaphorase. After electric stress stimulation, granulopectic activity is reduced in otherwise normal rats, whereas it appears to be increased in thymectomized animals. We implement three complementary techniques to quantify the number, energy, and electronic properties of trap states in nanocrystal (NC)-based devices. Continuous aspiration in prevention of pleural fistulas following pleurotomy in non-tuberculous pleural effusion. Both sensors are characterized in terms of surface mass density of immobilized AFM1 conjugate as well as affinity bound primary and secondary antibodies. This plavix medication wikipedia report demonstrated an acceptable esthetic result with no loss of ridge height or width. Besides providing information on the mechanism of strand cleavage by Flp, these results may contribute to the development of new synthetic DNA cleavage reagents that act by hydrolytic and not radical chemistry. The penton was expressed in Escherichia coli as a soluble C-terminal fusion with glutathione S-transferase (GST-Ad7PB) and was purified by single-step affinity chromatography.

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