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Manzolam (Alprazolam)

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Manzolam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Manzolam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Manzolam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Alprine, Altalin, Altok, Alzac, Anxiflu, Anzocalm, Cozac, Exiten, Himzolam, Kaprolam, Mebasap, Optizole, Prolam, Prozam, Tenan, Tenil, Tenolam, Tenschem, Tenzorid, Viprax, Visram, Wycalm, Zoltweet, Zopam

Similar Products:
Bystolic, Pepcid, Diovan, Duricef, Flagyl, Cialis, Chloromycetin, Mircette, Proplus, Mycoseal, Apentral, Cecold, Quinoten, Mendazole, Nifedipress, Glycirest, Premarin,

Also known as: Alprazolam


Manzolam XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Manzolam XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Manzolam XR may also be used for other purposes not listed in this medication guide.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Manzolam XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Manzolam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Manzolam dosage information

Side effects

The most common side effects associated with Manzolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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A spontaneous insertion in the agrocin sensitivity region of the Ti-plasmid of Agrobacterium tumefaciens C58. This review provides a brief presentation of the fabrication techniques and the main sample preparation procedures. Transgenic plants are attractive systems for production of therapeutic proteins because of the ability to do large scale-up at low cost, and the low maintenance requirements. Malignant tumours of the central nervous system in Kazakhstan--incidence trends from 2004-2011. These ternary codispersions were readily hydrolyzed by phospholipase A2, and they underwent a rapid change in turbidity. Vasodilative acting drugs, diuretics and surface active compounds were found to augment peritoneal solute clearances and water efflux by acting on peritoneal vessels or the serosal surface of the peritoneal membrane. However, dendritic cells (DC) have the capacity to resist these effects and remain functional during VSV infection. Neo-adjuvant treatment of rectal cancer with capecitabine and oxaliplatin in combination with radiotherapy: a phase II study. Comparison of the DG and UG demonstrated no difference for intra- or inter-rater reliability, with the DG yielding higher inter-rater ICC values for each of the 5 motions measured. We showed that this approach allows the identification of proteins that are expressed at nanogram per liter levels in the serum.

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The introduction of capsule endoscopy, balloon-assisted enteroscopy, spiral enteroscopy, and computed tomography (CT) enterography have served to overcome the limitations of older diagnostic tests. Smoking cessation behavior in older adults by race and gender: the role of health problems and psychological distress. Most recently this situation has changed greatly, however, and this seems to be due to a large extent to new test procedures. p35 and p25 expressions and Cdk5 kinase activity in primary cultured rat hippocampal neurons with X-ray exposure. Nanoparticle-induced apoptosis propagates through hydrogen-peroxide-mediated bystander killing: insights from a human intestinal epithelium in vitro model. Inguinal hernia: repair by extraperitoneal approach with an ivalon prosthesis. Relationship of heat shock protein 25 with reactive macrophages in thioacetamide-induced rat liver injury.

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Stratification of fractures sustained in child abuse according to specificity and an understanding of the several diseases that mimic abuse are helpful in the accurate diagnosis of child abuse. A new method is presented for mesoscopic simulations of particle dispersions in nematic liquid-crystal solvents. The evolution of brachytherapy prevacid solutabs 30 mg will be also impacted by technological considerations (end of the production of low dose rate 192 iridium wires). Remyelination of cytokine- or antibody-demyelinated CNS aggregate cultures is inhibited by macrophage supplementation. Service design projects sponsored by the Kansas State University Student Chapter of the IEEE EMBS. If surgery is required, various techniques via dorsal and ventral approaches, depending on the clinic and morphologic changes, can be applied. The effects of low dose DBcAMP on hemodynamics and metabolism in patients following open heart surgery. After system emptying, detection of tracer extravasation further strengthened the diagnosis of band leakage in all patients. There were no pathological findings in the right femoral heads of the MPSS-treated and saline-treated rats, as control for the contralateral injury. Integrated optical source of polarization entangled photons at 1310 nm.

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Developing exceptional scientific expertise apparently requires special educational experiences, but these necessary experiences are similar for the two sexes. Expression and role of TTF-1 in the rat suprachiasmatic nucleus. This review focuses on the different classes of sedative agents used in head injury, with a discussion of their role in the context of clinical pathophysiology. The effect of rostral deafferentation of the medial basal hypothalamus (MBH) on delta-9-tetrahydrocannabinol (THC)-induced changes in serum prolactin (PRL) concentrations was investigated in female rats having retrochiasmatic frontal cuts that transected the rostral hypothalamus. CD147 is involved in many physiological functions, such as lymphocyte responsiveness, spermatogenesis, implantation, fertilization and neurological functions at early stages of development. Twenty-six patients had signs of AVN and 49 patients had either other hip findings or normal hips. Cross-immunity and immune mimicry as mechanisms of resistance to the lantibiotic lacticin 3147. Molecular genetic studies have revealed that the development of NETs may involve different genes, each of which may be associated with several different abnormalities that include point mutations, gene deletions, DNA methylation, chromosomal losses and chromosomal gains. Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase side effects of adalat xl 20 mg TCPTP. Novel method to pseudoheterodyne a polarimetric fiber optic sensor.

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Non-chondritic sulphur isotope composition of the terrestrial mantle. From Paris to Stockholm: where does the European Alcohol Action Plan lead to?. Intensity and time course of inducible nitric oxide expression was found to not only depend on wavelength, but also on the mode of delivery, continuous, or pulsed irradiation. Neuron-specific enolase (NSE) as a tumour marker and comparative evaluation with carcinoembryonic antigen (CEA) in small-cell lung cancer. Hydroxylapatite in the surgical therapy of advanced periodontal disease. Strategies for prilosec otc generic farmers and policy makers to control nitrogen losses whilst maintaining crop production.

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Limited remyelination of CNS axons by Schwann cells transplanted into the sub-arachnoid space. Between regions, statistically significant differences in SCD incidence exist in young individuals. Clinical and pre-clinical protonix liquid form dosage data suggest the possibility of a facilitory role for norepinephrine (NE) in impulsive-aggressive behavior. The effect of cadmium (Cd) on both the absorption of important nutrients and the synthesis of low molecular weight thiols (LMWTs) was investigated in corn plants. The thymidine analogue BrdU is a powerful tool for analysing nucleotide incorporation in studies of DNA replication or repair. Although experimental evidence suggests the existence of genetic factors that cause intrinsic postzygotic isolation acting in embryos, the analysis presented here provided few candidate genes in embryos, which also corroborate previous studies showing a lack of ecological divergence between sympatric dwarf and normal whitefish at the larval stage.

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The constructs did not differ statistically in mean pullout forces (385.2 and 358.8 N for the 6.5-mm and 4-mm screw constructs, respectively). Medication adherence and health care utilization in pediatric chronic illness: a systematic review. Mechanisms of drug combinations: interaction and network perspectives. The potential for strained patient-physician relationship can be mitigated by patient-centred, goal-specific care with its emphasis on effective communication, a sense of timing and attention to the various dimensions of the illness experience. Either local or distal bystander effects may mediate antitumor effects. When detergent-solubilized proteins interact with hydrophobic or amphiphilic molecules in the presence of detergent micelles, the solubility of the latter species in the micelles must be included in both thermodynamic and kinetic treatments. Pregnancy related problems in mixed connective tissue disease, polydermatomyositis and scleroderma are analysed. The role of human hepatic cytochrome P450 isozymes in the metabolism of racemic 3,4-methylenedioxyethylamphetamine and its single enantiomers. Autonomic innervation of human airways: its clinical significance. There may have been a direct relationship between CNS involvement and PSS in only one patient presenting with an overlap-syndrome.

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PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens. The resurgence of off-pump CAB (OPCAB) prompted a reexamination of this practice. Branchial innervation and ciliary control in the ascidian Corella. We studied how health is ranitidine generic zantac information exchange systems are established by examining the decisions (and thus, indirectly, the values) of key stakeholders (health care providers) participating in a health information exchange pilot project in 3 Massachusetts communities. Results of chimney modification technique in ureterointestinal anastomosis of Hautmann ileal neobladder in bladder cancer. Incubation at 4 degrees C or with lidocaine (4 mM) partially prevented this effect of TPA, and the presence of sodium azide (150 mM) did so totally.

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Three-dimensional field distribution in the focal region of low-Fresnel-number axicons. The normal thymus was easily differentiated from the liver, spleen, and thyroid glands. As a second generation of chondrocyte transplantation, since 1996 we have been performing transplantation of tissue-engineered cartilage made ex vivo for the treatment of osteochondral defects of the joints. Effect of RMI-12,936 on fertilization and egg transport in the rabbit. To study the sensitivity, specification, detection limit and the practical use of MUCAP method for the detection of Salmonella in water. Laparoscopic-assisted radical gastrectomy for distal gastric cancer. However, individual ion diffusion (as a weighted average of charged and neutral ions) can be measured using pulsed-gradient spin-echo (PGSE) NMR. Measurement of ankle brachial index for assessment of atherosclerosis in patients with stroke. No correlation was observed between geographic origin and nucleotide distance, and thus from a genetic view, the Spanish and Californian isolates analyzed here could be considered members of the same population.

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