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Pranol (Alprazolam)

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Pranol is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
Acalm, Alprastan, Alzin, Alzot, Anlzium, Ansilumirm, Anzilum, Cooltime, Dazolam, Depsolam, Ecsit, Enxolam, Golprax, Kaprolam, Oclam, Ozolam, Pifzot, Pronext, Prozolam, Resolin, Selamb, Zodia, Zolax, Zoloid, Zolorest

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Neurontin, Trandate, Sildigra, Avapro, Yasmin, Pehatrim, Ascapil, Beltrax, Dolfre, Gastidom, Actirax, Nufaprim, Klarithrin, Trandy, Nizagara,

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Pranol. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Pranol for medical reasons, the best way to avoid a Pranol overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Pranol consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Pranol XR dosage information

Side effects

The most common side effects associated with Pranol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Pranol if you are pregnant. It could harm the unborn baby.

Do not use this medication if you are allergic to Pranol or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before you take Pranol, tell your doctor if you have asthma or other breathing problems, glaucoma, kidney or liver disease, a history of alcoholism, or a history of depression, suicidal thoughts, or addiction to drugs or alcohol.

Do not drink alcohol while taking Pranol. This medication can increase the effects of alcohol.

Pranol may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

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The burial records and skeletal collection produced comparable sex ratios. Frequency sweeps of several GHz are realized by automatically re-locking the diode laser to adjacent comb components during frequency sweep. It is taken up rapidly into the nucleolus, nuclear membrane and endoplasmic reticulum within 5 min, and retained in the nucleus for at least 24 h. A system for reversible optical data storage has been studied, using mixtures of polymers with liquid crystal molecules. Shortened OR time and decreased patient risk through use of a modular surgical instrument with artificial intelligence. The results suggest a role of the interaction between OsMPK20-4 and OsMPK3 in basic plant defense. Moreover, in view of the increasingly evident limited specificity of NSE, SYP should be considered the marker of choice for pancreatic NE neoplasms.

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It was demonstrated that alpha-l-fucose sugar residue might be the target of these lectins. In this study, we synthesized a GPI analog that was covalently linking to a PrP S230C mutant, resulting in S230C-GPI. N(G)-nitro-L-arginine (L-NOARG), an inhibitor of nitric oxide synthase (NOS), significantly enhanced NE-induced contraction in aortic rings from both control and T(4)-treated rats, and the enhancement was greater in rats treated with T(4) than control rats. Multipotent stromal cells skew monocytes towards an anti-inflammatory function: a role for HLA-G molecules. Porcine esophageal epithelial cells were seeded on the Fn bonded scaffold to test the cell growth promotion against the control unmodified PLLC nanofiber scaffold using tissue culture polystyrene (TCPS) plate as a reference. These CLEA-laccase aggregates showed more catalytic efficiency and more stabilities compared to free laccase against harsh conditions of thermal and chemical agents as well as high reusability. Bovine aortic endothelial cells were treated with either L-NAME or lipopolysaccharide (LPS) and interferon-gamma for 4 hr and subsequent leukocyte adhesion was measured. Ciprofloxacin and ampicillin had intermediate activity against tolerant cells while rifampicin, tetracycline and erythromycin had poor activity against tolerant cells.

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This is true whether the data analyzed are time courses observed at each voxel or a collection of summary statistics such as statistical parametric maps (SPMs). The physiological properties of neurons in anterior basal forebrain nuclei, including medial septum, the diagonal band of Broca and substantia innominata, have been described previously. From these results we conclude that the color-absorbing moiety of the product is the picrate molecule. Abdominal cytotomography (CT) scan showed hepatic infiltration with a tumor mass presumed to be hepatoblastoma. Two vaccination schedules were compared for immunogenicity and protection rates. However, the ability of SEs to re-create a computer-mediated world by using immersive displays does not annul the responsibility of designers to tailor interfaces to meet the task-dependant needs of users. The Mini-Social Phobia Inventory (Mini-SPIN) is a 3-item, self-rated screening instrument to assess social anxiety disorder, but its psychometric properties have not yet been examined in a sample seeking treatment for psychiatric disorders. Down-regulation of IgE and IgG4 antibodies to tetanus toxoid and diphtheria toxoid by covaccination with cellular Bordetella pertussis vaccine. AFM experimental results are studied and compared to two theoretical approaches: molecular and thermodynamic.

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Presence of Australia antigen, histocompatibility (HL-A) antigens, and autolymphocytotoxins (CoCoCy) during different forms of hepatitis and cirrhosis. ERSET was designed to assess the safety and efficacy of early surgical intervention compared to continued pharmacotherapy. This work presents an overview of the current understanding of anthrax pathogenesis and recent advances made, particularly after 2001, for the successful management of anthrax and outlines future perspectives. A significant apoptosis-related increase in the sub G1 peak of the cell cycle in both breast cancer cell lines was also observed. Congenital hemihypertrophy with adrenal adenoma and medullary sponge kidney.

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Chronic inflammation is considered as an important factor in the pathogenesis of lung cancer. Certain types of glomerulonephritis develop typically as the result of focal infection, and may recover following effective treatment of the infective focus at cause. We analyzed the effect of CD as well as normalized distance (ND) using expression data in six eukaryotic species: yeast, fruit fly, worm, rat, mouse and human. Recruitment and retention of Latino children in a lifestyle intervention. Measurements and calculations of the energy fluence rate in a scattering and absorbing phantom at 633 nm. The significance of circulating tumor cells (CTCs) in blood and of disseminated tumor cells (DTCs) in bone marrow (BM) in patients with early stage breast cancer is unclear. Thus, the present findings, taken together with reports that the overall activity of central opioid neurons is enhanced during stress, support the view that the decline in GH is due to the overriding inhibitory influence of an independent nonopioid mechanism. Two hundred and three newly diagnosed patients with gastric or oesophageal cancer had serum CRP and cytokine concentrations determined by ELISA.

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In the present study, novel allelic variants at Glu-B3 locus were cloned to provide gene resources for wheat quality improvement. The larger O2 deficit during supine exercise resulted from a significantly greater VO2 halftime compared to that of the upright response. The aim was to develop and validate a new biomarker of non alcoholic steato hepatitis (NASH) the NashTest (NT) in patients with NAFLD. 1980 presidential address to the american academy for cerebral palsy and developmental medicine. At the age of 52 weeks, patients with HLHS had significantly lower scores in all 4 AIMS subscales, whereas patients with UVH had lower scores only in the prone and standing subscales. In each functional region of interest (fROI), measures of neural similarity were compared to behavioral ratings. The periphery of the lobules tends to be more cellular than the center.

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The characterization of these compounds was mainly based on one functional read-out system, although S1P(3) receptors are known to activate different signal transduction pathways. In addition we use a comprehensive plasmid library of MHC class IIB alleles to determine the nucleotide sequence of alleles represented by RSCA allele peaks. Our findings suggest that different patterns of TLRs and chemokines were induced in the initiation and modulation of immune response to rotavirus and coxsackievirus B3 infection. In a severe case of TTTS in monoamniotic twins we observed donor anuria to appear after hydrops in the recipient. Risk assessment of DM-related morbidity, hospitalizations and disabilities using data from the medical literature and health statistics on the population. SL offers significant benefit to patients with resectable pancreatico-biliary cancers in avoiding non-therapeutic laparotomy and should be adopted in routine clinical practice in a judicious algorithm. Rather neurontin capsule 300 mg than focusing the content of educational conferences on current knowledge of labor and delivery, an important next step is modeling woman- and family-centered care. The paper deals with the effect of assortative matings on some parameters of population structure.

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In addition, this model requires PND and other laboratory and clinical facilities as backups. It is concluded that complete lysis of the blood in irrigation fluid is necessary for reliable calculation of blood loss. The course was complicated by recurrence in the latter two and refractoriness to chemotherapy and death in one. Toward critical evaluation of the role(s) of molecular biomarkers in the management of bladder cancer. Expansile hydrogel devices have led to increased progressive occlusion, while degradable polymer devices led to an increased rate of thrombus organization compared with platinum coils. Enhanced computed tomography was performed on postoperative day 9 showed occlusion of the right pulmonary artery by a thrombus. P3MC: a double blind parallel group randomised placebo controlled trial of Propranolol and Pizotifen in preventing migraine in children. Capacitive micromachined ultrasonic transducers (cMUT) have become an alternative to piezoelectric transducers in the past few years. Epidemiological, clinical, and experimental observations have led to the hypothesis that the risk of developing chronic diseases in adulthood is influenced not only by genetic and adult lifestyle factors, but also by environmental factors during daily max dose of xanax early life. Our data indicate that light-induced activation of IR/PI3K/Akt results in the translocation of HK-II to mitochondria.

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Two related gadolinium aquo carbonate 2-D and 3-D structures and their thermal, spectroscopic, and paramagnetic properties. Intersubject PK variability is substantial and is not correlated with body size or age but more likely due to differences in metabolite formation that may be genetic in origin. The Tampon Test reflects a real life experience that is reliable, with good construct validity as shown by the breadth of correlated outcome measures. Genomic DNA from 49 MDS, 38 AML and 37 AA patients and 276 controls was analysed using the polymerase chain reaction (PCR). Electroencephalographically, the FeCl3 epileptogenic focus remained active for a duration longer than that of the cobalt focus. To investigate the effects of angiotensin II (Ang II) on corticotropin- taking diflucan while on antibiotics releasing hormone (CRH) and argipressin (AVP) release from median eminence (ME) of hypothalamus during acute hypoxia in rats.

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To evaluate efficacy and outcome of tamsulosin therapy for 4 mm-10 mm uncomplicated distal ureteral stones. It was suggested that compounds showing an IC(50) value ratio of 1 scavenged the common species for nitration and oxidation, while the indole derivatives and ADPP preferably scavenged the nitrating and oxidizing species, respectively. Task-irrelevant alpha components were sorted out and their projections were reduced by proper bipolar electrode placement for improving the BCI performance. Many studies had methodologic weaknesses in their design and adjustment for confounding factors. Visual improvement in an zocor statin drug adult amblyopic eye following radiation-induced visual loss in the contralateral eye. The study demonstrated TCDD exposure in this community, occurring most likely through the aerial route, and most probably from fugitive emissions during manufacture. A simplified approach to teaching medical students ocular movements and the rationale in testing the oculomotor, trochlear, and abducent nerves.

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The sclerosing mechanisms of the two medicines and their clinical applications were discussed. A subgroup analysis was conducted for graduates with more than 10 years after residency. Studying the mechanism of RNA separations using RNA chromatography and its application in the analysis of ribosomal RNA and RNA:RNA interactions. Effect of sucrose, stevia and xylitol on rheological properties of gels from blends of chestnut and rice flours. In vitro studies with purified wild type and mutant (E240K) proteins. The high mannose glycans from bovine ribonuclease B isomer characterization by ion trap MS. Cryptococcus gattii is responsible for an expanding epidemic of serious infections in Western Canada levaquin dosing adult and the Northwestern United States (Pacific Northwest). Results from the PCoA/MST analysis and the Neighbor-joining consensus tree showed that 7 pairs presented high similarity and the other 3 showed moderate levels of similarity. Review of occupational epidemiology of chromium chemicals and respiratory cancer. The purification involves extraction of membranes with dodecyl maltoside and two successive DEAE column chromatography steps.

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The p110RB1 protein state was detected by immunohistochemical staining using the polyclonal antibody to the RB1 products. The value of the lamina dura in the diagnosis of generalised skeletal abnormalities has been defined. The same measurements were performed for the normal ankle, the fused ankle, and after total ankle replacement by the AGILITY, HINTEGRA, and S.T.A.R. Functional differences between speech and non-speech within the irrelevant sound effect were investigated using repeated and changing formats of irrelevant sounds in the form of intelligible words and unintelligible signal correlated noise (SCN) versions of the words. This review discusses the existing evidence in support of the latter hypothesis. Lateral specialization and verbal/spatial ability in preschool children: age, sex and familial handedness differences. This review summarizes the current information on the molecular mechanisms by which NSAIDs and mesalazine could interfere with CRC cell growth and survival. Common garden experiment reveals pathogen isolate but no host genetic diversity effect on the dynamics of an emerging wildlife disease. For high diffusion, the activated kinase molecules quickly leave the vicinity of the cell membrane and cannot efficiently activate the receptors. The pneumococcal (Pn) ECL assay is based on the Meso Scale Discovery (MSD) technology which utilizes a Sulfo-Tag-labeled anti-human IgG antibody that emits light upon electrochemical stimulation.

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