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Prilosec (Omeprazole)

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Prilosec is a medicine that reduces the amount of acid produced in your stomach. It helps treat acid-related diseases of the stomach and intestine such as heartburn, acid reflux, and peptic ulcer disease.

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Also known as: Omeprazole


Prilosec (omeprazole) is a proton pump inhibitor that decreases the amount of acid produced in the stomach.

Prilosec is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions caused by excess stomach acid. Omeprazole is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).

Prilosec may also be given together with antibiotics to treat gastric ulcer caused by infection with Helicobacter pylori (H. pylori).

Over-the-counter Prilosec OTC is used in adults to help control heartburn that occurs 2 or more days per week. Prilosec OTC must be taken as a course for 14 days in a row.


Generic Prilosec OTC is available in tablets (10 mg, 20 mg, 40 mg) and capsules. You should take Generic Prilosec OTC every day for 14 days. Do not take Generic Prilosec OTC more than one pill a day. Take Generic Prilosec OTC before eating. Do not break, crush or open a delayed-release capsule. Your symptoms may get better before the condition is completely treated. Take Generic Prilosec OTC with water. If you want to achieve most effective results do not stop taking Generic Prilosec OTC suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Prilosec are:

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Do not take Generic Prilosec OTC if you are allergic to Generic Prilosec OTC components. Do not take Generic Prilosec OTC if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Prilosec OTC is not used for immediate relief of heartburn symptoms. Do not take more than one tablet of Generic Prilosec OTC a day (24 hours). Be careful with Generic Prilosec OTC if you suffer from or have a history of liver disease, bloody or black stools, heartburn which lasts for over 3 months, vomit that looks like blood or coffee grounds, frequent chest pain, heartburn with wheezing, stomach pain, nausea or vomiting, trouble or pain with swallowing, unexplained weight loss. Take Generic Prilosec OTC with care if you are taking such medicines as disulfiram (Antabuse),a blood thinner (warfarin (Coumadin)),tacrolimus (Prograf),cyclosporine (Gengraf, Neoral, Sandimmune), phenytoin (Dilantin),ampicillin (Omnipen, Principen),itraconazole (Sporanox) or ketoconazole (Nizoral),insomnia or anxiety medicines (diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), temazepam (Restoril), clorazepate (Tranxene), chlordiazepoxide),iron (Feosol, Mol-Iron, Fergon, Femiron and the others), atazanavir (Reyataz), theophylline (TheoBid, Theo-Dur, Theochron, Theolair, Elixophyllin, Slo-Phyllin). Avoid alcohol. Do not stop taking Generic Prilosec OTC suddenly.

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