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Sustiva

Sustiva works by preventing the HIV virus from multiplying in your body. It helps control the infection and makes your immune system work better. This lowers your chances of getting complications such as new infections and improves your quality of life.

Other names for this medication:
Cytocom, Duovir, Efavir, Efavirenz, Efcure, Efferven, Emduo, Estiva, Evirenz, Lamivir, Lazid, Odivir, Retrodel, Revenz, Tenola, Trioday, Trustiva, Viraday, Viranz, Virocmb, Virolis, Vonavir, Zidolam

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Also known as: Efavirenz

Description

Sustiva (efavirenz) is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Sustiva is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).

Sustiva is for adults and children who are at least 3 months old and weigh at least 8 pounds. This medicine is not a cure for HIV or AIDS.

Dosage

Usual Adult Dose for HIV Infection:

600 mg orally once a day Comments: -This drug should be used with a protease inhibitor and/or NRTIs. Use: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Usual Adult Dose for Nonoccupational Exposure:

US CDC recommendations: 600 mg orally once a day Duration of therapy: 28 days Comments: -This drug should be used with (lamivudine or emtricitabine) plus (zidovudine or tenofovir); recommended as the preferred NNRTI-based regimen for nonoccupational postexposure prophylaxis of HIV infection. -Prophylaxis should be started as soon as possible, within 72 hours of exposure. -Not approved by US FDA.

Usual Adult Dose for Occupational Exposure:

US Public Health Service working group recommendations: 600 mg orally once a day Duration of therapy: 28 days, if tolerated Comments: -An alternative antiretroviral agent for use as HIV postexposure prophylaxis only with expert consultation -Prophylaxis should be started as soon as possible, preferably within hours after exposure. -The optimal duration of prophylaxis is unknown and may differ based on institution protocol. -The most current therapeutic guidelines should be consulted for more information. -Not approved by US FDA.

Usual Pediatric Dose for HIV Infection:

3 months or older: 3.5 to less than 5 kg: 100 mg orally once a day 5 to less than 7.5 kg: 150 mg orally once a day 7.5 to less than 15 kg: 200 mg orally once a day 15 to less than 20 kg: 250 mg orally once a day 20 to less than 25 kg: 300 mg orally once a day 25 to less than 32.5 kg: 350 mg orally once a day 32.5 to less than 40 kg: 400 mg orally once a day 40 kg or more: 600 mg orally once a day Use: In combination with other antiretroviral agents, for the treatment of HIV-1 infection

Detailed Sustiva dosage information

Overdose

If you overdose Sustiva and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sustiva are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol can increase certain side effects of efavirenz.

Using this medicine will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

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Lower-Risk Cannabis Use Guidelines: A Comprehensive Update of Evidence and Recommendations. Given the decision uncertainty and the variation in care provided by health-care professionals, we then determined the EVPI and EVPIM. Recovery of laccase from processed Hericium erinaceus (Bull.:Fr) Pers. Several clinical studies have shown that hydroxyethyl starch (HES) may be as effective and safe as, but less expensive than, albumin when used for perioperative plasma volume replacement (PVR) in children. Comprehensive evaluation of intracranial tumours adjacent to large blood vessels could be achieved with the WBCTP technique. Pressure mat variables of stance time and stride velocity varied greatly among calves, whereas impulse and maximum forces varied little. In the cardiac valves affected by chronic rheumatic valvulitis, the endothelial layer denuded extensively, even in the regions where only slight thickening was noticed in the intravalvular tissues. High-level protein secretion into blood circulation after electric pulse-mediated gene transfer into skeletal muscle. Antistreptolysin and antistaphylolysin reaction in chronic polyarthritis and spondylitis ankylopoetica.

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Adenosine A1 receptors mediate the intracisternal injection of orexin-induced antinociceptive action against colonic distension in conscious rats. The correlation coefficients and analysis of covariance showed good reliability and validity of all outcome measures. In order to combine the flexibility and expressive power of natural language with the computational tractability of structured data, the electronic health record based on structured narrative offers new perspectives. vulgaris bacterial rhizosphere revealed a different composition according to soil type and plant genotype. Efforts have been made to characterize executive functions (EF) in anorexia nervosa (AN) both in the acute stage of the illness and after weight gain, yet many questions remain. A series of studies has also shown that a reduction in short intervals of phonation, those from 30 to 200 ms, is associated with decreased stuttering. Acupuncture offers the possibility to improve the healthcare assistance by transcending the reification of human beings resulting from the pre-eminence of the biomedical paradigm and facilitating cooperation between disciplines. Short-term lisinopril treatment in old rats worsens impairment of angiotensin-induced reflex bradycardia.

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International workshops such as IPHIE provide a unique opportunity for graduate student learning and knowledge sharing. The proteome of the swimming cyprid was distinctly different from that of other life stages and had about 400 spots. Meal-induced thermogenesis in lean and obese prepubertal children. Characterization of a DAPI-RIT-DAPI system for gas-phase ion/molecule and ion/ion reactions. In this review, we discuss both the involvement of chromatin in stress responses and the current evidence on somatic, intergenerational, and transgenerational stress memory. Pulmonary lasmacytoma as the first manifestation of IgM multiple myeloma: a case report and literature review. Identifying accelerometer nonwear and wear time in older adults. The safety and efficacy of osimertinib for the treatment of EGFR T790M mutation positive non-small-cell lung cancer. Equine recurrent uveitis (ERU) is a valuable spontaneous model for autoimmune uveitis and analyses of differentially expressed proteins in ERU unraveled changed protein clusters in target tissues and immune system.

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