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Valium (Diazepam)

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Diazepam, first marketed as Valium, is a medication of the benzodiazepine family that typically produces a calming effect. It is commonly used to treat a range of conditions including anxiety, alcohol withdrawal syndrome, benzodiazepine withdrawal syndrome, muscle spasms, seizures, trouble sleeping, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, or injected into a vein. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects may take 40 minutes to begin.

Other names for this medication:
Almpose, Alpazepam, Alzepam, Anxol, Calmpose, Calmtack, Campin, Daize, Depresom, Diaze, Diazecalm, Diazeco, Dipax, Direc, Dizapam, Dizep, Elcion, Elpose, Imilor, Imipam, Imlor, Nupose, Osopose, Paciquil, Paxum, Sleecalm, Vipinta, Zeopse

Similar Products:
Minocin, Plavix, Famvir, Cleocin, Prilosec, Symmetrel, Colospa, Cetra, Petrox, Walaphage, Rogaine, Zycin, Borophen, Befine, Nofloxan,

Also known as: Diazepam


Valium is used to treat anxiety, alcohol withdrawal, and seizures. It is also used to relieve muscle spasms and to provide sedation before medical procedures. This medication works by calming the brain and nerves. Diazepam belongs to a class of drugs known as benzodiazepines.

Take this medication by mouth with or without food as directed by your doctor. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition, age, and response to treatment. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Properly stop the medication when so directed.


Take Valium exactly as prescribed by your doctor. Follow the directions on your prescription label and read all medication guides. Your doctor may occasionally change your dose. Never use diazepam in larger amounts, or for longer than prescribed. Tell your doctor if you feel an increased urge to use more of this medicine.

Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it. Selling or giving away this medicine is against the law.

Valium should be used for only a short time. Do not take this medicine for longer than 4 months without your doctor's advice.

Do not stop using this medicine suddenly, even if you feel fine. Stopping suddenly may cause increased seizures or unpleasant withdrawal symptoms. Follow your doctor's instructions about tapering your dose.

You will need frequent medical tests.

Store at room temperature away from moisture, heat, and light. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Detailed Valium dosage information


Seek emergency medical attention. An overdose of diazepam can be fatal. Overdose symptoms may include extreme drowsiness, loss of balance or coordination, limp or weak muscles, or fainting.


Store at room temperature away from moisture, heat, and light. After you have stopped using this medicine, flush any unused pills down the toilet.

Keep track of the amount of medicine used from each new bottle. Valium is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Valium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid drinking alcohol. Dangerous side effects or death could occur.

Grapefruit may interact with diazepam and lead to unwanted side effects. Avoid the use of grapefruit products.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

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To investigate their involvement in Alzheimer disease, we identified three isoforms of muCANP (calpain I) in human postmortem brain corresponding to an 80-kDa precursor and two autolytically activated isoforms (78 and 76 kDa). The program has expanded to develop a partnership with the European Pediatric Orthopaedic Society. Despite these drawbacks, GEMS can play a significant part in the analysis of finger dose patterns and assist in dose reduction. Regulation of Gs alpha protein was more complex in that Gs alpha was unaffected in the other tissues tested. The follow-up cystoscopy revealed adequate healing of the bladder. The symmetrical nature of midprediction causes the spikes to appear in the error signal with their original basewidths. Different RNA and protein expression of surface markers in rabbit amniotic fluid-derived mesenchymal stem cells. Although the evolution of lecithotrophy involved substantial changes to larval development and morphology, it is not known to what extent changes in gene expression underlie the developmental differences between species, nor do we understand how these changes evolved within the context of the well-defined gene regulatory network (GRN) underlying sea urchin development.

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The ovarian response to standard gonadotropin stimulation is influenced by AMHRII genotypes. The identification of cultivars that have consistently lower radiocaesium and/or radiostrontium concentration ratios suggests that cultivar selection or substitution may be an effective remediation strategy in radiologically contaminated areas. These include ongoing cellular and genomic comparisons that, we will argue, have generally undermined all attempts to identify a synapomorphic trait that defines the Fungi. Results suggest that traumatized adolescents, indeed, have more difficulty with semantic personal memory than non-traumatized adolescents. In cells expressing short hairpin RNAs directed against CoREST, Hsp70 cannot repress HSF1-dependent transcription.

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Hypertensive effects of mianserin have not been described so far. Chloramphenicol eye drops in the treatment of conditions indicative of maxillary sinusitis. The natural resources are finite and highly prone to degradation by the misuse of land and mismanagement of soil. DSM 30002, Arthrobacter nicotianae DSM 20123 as well as Issatchenkia orientalis DSM 70077 and Rhodococcus erythropolis DSM 311 were characterized by the sensor technique by injection of 30 different substrates and substrate mixtures. Scarf pin-related hijab syndrome: A new name for an unusual type of foreign body aspiration. The indirect effect as related to loss body weight was shown to lead to a significant decrement in heart weight. SCH 54388 was markedly free of toxic side effects up to doses of 300 mg/kg, sc. ALP carried by Si NPs convert nonelectroactive substrate into the reducing agent and the latter, in turn, reduce metal ions to form electroactive metallic product on the electrode. In a separate session intravenous phenylephrine (200 microg) and l-methamphetamine (5 mg) were given to define alpha agonist pharmacology and bioavailability.

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Furthermore, activation of STAT1 binding to this site was important for the synergistic response seen following the stimulation with both IFN-gamma and LPS. In addition, immunocytochemical examination of tissues from shrimp experimentally infected with YHV gave a positive reaction, while tissues from uninfected control shrimp or shrimp experimentally infected with WSSV did not. The rhesus macaque is an important biomedical model organism, and the Tulane National Primate Research Center (TNPRC) has one of the largest rhesus macaque breeding colonies in the United States. We investigate the effects of sodium valproate, a gamma-aminobutyric acid transaminase inhibitor, on the clinico-physiologic state after ileoanal anastomosis. Evaluation of magnetic resonance colonography at 3.0 Tesla regarding diagnostic accuracy and image quality. Net transport of FFA was suppressed to equally low levels in obese and lean subjects, though at the expense of higher insulin concentrations in the obese.

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The result demonstrate that atorvastatin and amlodipine fixed dose combination is favourable to reach double goals on blood pressure and LDL-cholesterol. During hibernation of the animals, 11-oxycorticosteroid secretion exhibits intrinsic endogenous rhythm. These findings also show the importance of facility based training programs for nurse aides on a global level. Although the rehabilitation of patients with chronic obstructive pulmonary disease (COPD) improves both exercise capacity and quality of life, a standard protocol for COPD patients has not been established. Staphylococcus aureus, an increasingly important pathogen, acquires iron from host haem via elaboration of the iron-regulated surface determinant system (Isd). Lack of access to appropriate training programs and interdisciplinary politics is limiting the use of this potentially valuable clinical information. A mixing timescale can be obtained by analysis of cell trajectories from live imaging.

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Available evidence indicates the effectiveness of many ceramic systems for numerous clinical applications. Our results suggest that collagen is an important protein that interacts with HOCl to form AOPPs, and consequently, collagen-AOPP formation is related to human neutrophil activation and cell death. Cellular calcium signals: nature, registration, and quantitative estimation. However, when performed late, it results in similar rates of limb salvage as compared with early fasciotomy but at the increased risk of infection. Fecal samples were collected and microbiota composition was studied before and six months post treatment using 16S rRNA gene sequencing and qPCR. The objective is to decrease the use of tobacco by young people and consequently reduce the future morbidity and mortality from tobacco. The second harmonic generation (SHG) response at the air-water interface from the tyrosine-containing natural iturinic cyclo-lipopeptides mycosubtilin, iturin A and bacillomycin D is reported.

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Maternal obesity is a global epidemic affecting both developed and developing countries. Therefore, permissiveness for secreting only a subset of SPI-2 effectors may be instrumental for dormancy. dentata brain to further examine its relationship to polyethism. Demyelination is the pathologic hallmark of the human immune-mediated neurologic disease multiple sclerosis, which may be triggered or exacerbated by viral infections. One of the important indicators to compare the prevalence and incidence of the disease is a change in the trend. In contrast, few intracellular parasites were observed in wild-type littermates and these animals survived for at least 60 d after infection. Gender-stratified, age-standardized cancer incidence rates were calculated following the direct method. Blood pigment: physiological functions and certain pathological syndromes. However, sufficient postoperative pain therapy is necessary to free the patients of pain to the same degree as with neuroleptanaesthesia.

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Is retrograde ureterography indicated in pelviureteric junction obstruction?. Studies of monogenic gastrointestinal diseases have revealed molecular pathways critical to gut homeostasis and enabled the development of targeted therapies. Effects of exercise training on skeletal muscle glucose uptake and transport. Acute obstructive hydrocephalus caused by a migrating intraventricular calculus. A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa.

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Increased levels of serum Hb and CRP and decreased levels of haptoglobin were seen in Danish malaria patients. We then calculated separate transition probabilities for each of these phases for each participant. ORTH1- ORTH5 are predicted to encode proteins that contain one plant homeodomain (PHD), two really interesting new gene (RING) domains, and one set ring associated (SRA) domain, whereas ORTHlike-1 encodes a protein with only one RING and SRA domain. Often, use of the six steps described in this article brings fairly rapid functional improvement and prevents recurrences, with a minimum of medical intervention. We selected six co-expression-based methods with good performance in evaluation studies from the literature: Partial correlation, PCIT, ARACNE, MRNET, MRNETB and CLR. Part B: Parameter estimation and simulation of variable decelerations. To improve symmetry and therefore the sitting posture, surgery is also indicated for profoundly disabled patients, sometimes making foot operations necessary. GSTM1 and GSTT1 gene polymorphisms were studied in Shorians, Teleuts, and Caucasians of the Kemerovo region. Human follicle stimulating hormone receptor trafficking and hormone binding sites in the amino terminus.

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Furthermore, biopsy should be considered in chronic and relapsing bone pain and swelling unresponsive to treatment. The effect of mental comorbidity on service delivery planning in primary care: an analysis with particular reference to patients who request referral without prior assessment. Discovery of risk alleles may be important for prediction and management of RDS risk. There are different models to explain the high rates of comorbidity between psychosis and SUD. Epidemiological approaches, particularly case-control studies, seem to provide the best method for quantifying the relative importance of the various sources of M. The key of the method is using the recurrence plots hierarchically, which allows us to preserve the underlying regularities behind the original time series.

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Since functions respect the cyclic events in proliferation and are not influenced by polyploidization. Percutaneous interventions are still limited by our need to treat thrombus, alter or passivate the arterial wall, and deliver new treatments into or through the arterial wall. Prolonged enhancement of tumours might be a common sign (6/6) in Xp11.2 translocations. The substantially elevated serum enzymatic activities of alanine/aspartate aminotransferase, sorbitol dehydrogenase and gamma-glutamyltransferase due to CCl(4) treatment were dose dependently restored towards normalization. Moreover, MPA did not affect the antitumor activity of 5-FU against MPA-insensitive mouse breast carcinoma FM3A, or rather augmented its antitumor activity against MPA-sensitive human breast carcinoma MCF-7. albicans to plastic materials, can be partially inhibited with an mAb directed against cell wall polysaccharides of C. Bisphosphonates are the most logical choice when specific medical treatment of PBC-associated osteoporosis is indicated, as well as for preventing bone loss during glucocorticoid treatment and after liver transplantation. This allowed us to analyse call properties of males as a function of their infection status. The results of our previous study demonstrate the anti-angiogenic potential of an extract of Gleditsia sinensis thorns, which has been traditionally used in Korean medicine to remedy diverse diseases, including tumors. In this scenario we developed a fast DNA extraction method without any purification step from fresh and processed seafood, suitable for any PCR analysis.

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A correlated study of the cytogenetic effect of Isoniazid (INH) on cell systems of mammals and man conducted by thirteen laboratories. All patients had positive cultures for microorganisms from their corneas or contact lens cases or had pathognomonic findings of pseudodendritic subepithelial infiltrates and radial keratone-uritis. Nephrotoxicity in goats caused by dosing with a water extract from the stems of Narthecium ossifragum plants. No significant difference in duration of lymph node dissection, chest drainage volume, drainage duration, or number of dissected lymph nodes was observed between the study group and the controls. Repeated stress led to antipodal directions in immune system and cytochrome P450 activities of normotensive and hypertensive rats. Dietary habits and psychosocial stress are potentially modifiable factors, which should be taken into account in intervention programs among women with low SES. Lumenal proteins involved in respiratory electron transport in the cyanobacterium Synechocystis sp. Thus, in the present study, with only minor modifications, the same equipment was used for both direct and indirect determinations of systolic blood pressure. Thus, a supramolecular chiroptical switch is obtained based on supramolecular chirality transfer and dynamic covalent chemistry. Treatment of deltoid contracture in adults by distal release of the deltoid.

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We report a case of a young patient with ulcerative colitis, who developed multiple site arterial and venous thrombosis, all occurring within short intervals of each other. Solar keratoses belong to the list of clinically invisible dermatoses, as the loss of their horny layer may create the illusion that they have disappeared, and numerous subclinical lesions can be highlighted by 5-fluorouracil therapy. Asp fl inhibited protein synthesis in RAW cells with an IC50 of 4.5 nM and also degraded ribosomal RNA of RAW cells at a similar concentration. The aim was to determine which of 2 commonly used nonfold donor insertion techniques was advantageous for initial Descemet stripping automated endothelial keratoplasty (DSAEK) cases. We also observed that VRP treatment of HEL-JW cells resulted in the phosphorylation of the cytoskeletal protein paxillin. N-Ethylmaleimide-sensitive fusion protein contains high and low affinity ATP-binding sites that are functionally distinct. Quantifying the Impact of Nanoparticle Coatings and Nonuniformities on XPS Analysis: Gold/Silver Core-Shell Nanoparticles. Musculoskeletal ultrasonography in routine rheumatology practice: data from Central and Eastern European countries. Leprosy nerve abscess in Indian male, misdiagnosed as tuberculous lymphadenitis and neuroma. Pre-clinical evaluation of a microwave planar array applicator for superficial hyperthermia.

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Therefore, further investigations are required, particularly on proteinuria management and the occurrence of spontaneous labor. Further, the MUC4-overexpressing SKOV3 cells exhibited an increase in the phosphorylation of focal adhesion kinase (FAK), Akt and ERK, downstream effectors of HER2. Inhibition of AKT would change the status of downstream effectors in the PI3K/AKT pathway: (1) inhibition of AKT up-regulated expression of cell cycle regulatory factors of downstream - P21 and P27 which repressed cell cycle and inhibited proliferation of tumor cells. To determine the importance of bacteriobilia and fungibilia in patients with endoscopic treatment of biliary complications after orthotopic liver transplantation (OLT). The poorly know mechanism is immunological, with formation of immune complex deposits on the endothelial cells and at the dermo-epidermal junction, fibrinoid necrosis of small vessels and cellular reaction which is lymphocytic. Moreover, involvement of the sphenoid sinus in multiple myeloma resulting in extrinsic optic nerve compression is extremely rare. Clinically significant changes in SBP, HR, and SpO(2) , however, were similar in the midazolam and control groups. Management should be targeted to patient comfort, prevention of infection, and maintenance of function.

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Screening blood donors for specific HTLV-I/II antibody has been implemented in Japan, United States, and recently in France. Comparisons of single albenza cost and combined stress effects on growth and biomass traits exhibit patterns of allele effects that suggest attenuating interactions among physiological signaling steps in drought and ultraviolet radiation stress responses. Vorinostat is a potential precipitant for severe gastrointestinal toxicity. Our experiences show that careful histological evaluation of lymphoid orbital masses is necessary for correct diagnosis, especially since this has great impact on treatment and prognosis. Shear-stress causes polarized change in cytoplasmic calcium concentration in human umbilical vein endothelial cells (HUVECs).

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Association of genetic polymorphisms with embryonic mortality in the chicken. Apoptosis induced by hyperthermia and verapamil in vitro in a human colon cancer cell line. The above, together with other findings, have important implications for our understanding of the aetiology of widely differing conditions such as protrusive and retrusive malocclusions, dysphagia and sleep apnoea, as well as the development of novel food products. Clinical prediction rules are evidence-based tools that combine multiple predictors to estimate the probability that a particular outcome in an individual patient will occur. Lung edema may worsen hours after the immediate postreperfusion period, even though lung apoptosis and inflammation are reduced or show no change, respectively. This concept of the oral health-general health connection is now supported by sound and rational evidence-based observations. Tongue cleaning should be incorporated into current nursing procedures. Rat liver peroxisomal and mitochondrial fatty acid oxidation in sepsis. Role of adrenal in regulation of corticotropic anterior pituitary secretion. Testosterone administration to men with testosterone deficiency syndrome after external beam radiotherapy for localized prostate cancer: preliminary observations.

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Building a large-scale perioperative anaesthesia outcome-tracking database: methodology, implementation, and experiences from one provider within the German quality project. Industrial psychology at the Tenth Congress of Industrial Medicine. To our knowledge, this is the first case report of rosuvastatin-induced AIN. GHIs could assist in these strategies, provided that they are flexible enough to incorporate country-specific needs in terms of funding, that they coordinate at global-level and minimise conditionality for countries. Among this group there were 2 fertilizations and 1 pregnancy with 9 in-house cases, and 3 fertilizations and 2 pregnancies with 6 transported specimens. IL-6 as a regulatory factor of the humoral response during pregnancy. Estrogen administration will preserve bone mass in postmenopausal women, and the optimal intake of calcium and vitamin D is being evaluated. Conversion factors for vegetable and animal foods for human consumption. Instead the ego-development with all its aspects and the improvement of the capacity for emotional relationship is most important. The association between low-density lipoprotein (LDL) and a series of well characterized dermatan and chondroitin sulfates has been investigated by means of the fluorescence anisotropy technique with competition experiments using a fluorescein-labeled high LDL-affinity heparin fraction as a reference.

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Quantitation of cell surface microvilli was determined by using a computer with input from a digitising tablet from what is generic of lexapro scanning electron micrographs. They were further tested for their antioxidant potentials using DPPH assay, hydrogen peroxide scavenging assay, nitric oxide scavenging assay and ferrous antioxidant reducing potential assay. One-half inch thick polyurethane foam is recommended for use in postoperative casts to avoid complications seen with postoperative swelling. The stability of small unilamellar vesicles (SUV) made from negatively-charged phosphatidate by ultrasonication or pH-jump has been investigated. It showed greater activity against Haemophilus strains than did cephalexin and inhibited beta-lactamase-producing Haemophilus isolates. Noctiluca and copepods grazing on the phytoplankton community in a nutrient-enriched coastal environment along the southwest coast of India.

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Alterations in the synthesis and degradation of extracellular matrix occur during atherogenesis. In particular, the study of Ricin/lactose and Hevein/chitobiose complexes is detailed. DOSI predicted pCR in patients with breast cancer with moderate accuracy. It is based on the establishment, by means of electronic appliances, of a zone without heatflow from the deep tissues. Sensitivity to 27 microg/g (approximately 2 nM) MNPs within tissue phantoms is achieved by filtering paramagnetic from diamagnetic vibrations. Left-sided pain which had been minimal before microvascular decompression (MVD) became intolerable immediately after right-sided surgery, yet responded to mild doses of carbamazepine for almost a year. Advances in gerontology research and education: perspectives from the Australian Association of maximum dosage of coreg per day Gerontology.

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Both tracers labeled axons and terminal arbors more prominently than comparable material studied by the widely used methods of anterograde fiber-filling with horseradish peroxidase or cobalt cozaar side effects reviews . On the other hand, osteogenic differentiation in the adipose tissue MSCs may involve the p44/42 MAPK pathway. DWL is in direct relation to daytime energy output, when metabolic expenditure exceeds the low rate of acquisition of exogenous calories. Prophylactic recombinant hepatitis B vaccine in patients undergoing orthotopic liver transplantation. This case emphasizes the importance of ruling out intra-abdominal trauma in any drug addict presenting with acute abdomen. A Wiskott-Aldrich syndrome protein is involved in endocytosis in Aspergillus nidulans. Analysis included: rate of episio- and perineotomy, perineal trauma, postpartum haemorrhage and fetal injury.

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We here show that bloodstream forms can be obtained by transient transfection of procyclic forms with a circular plasmid designed for expression neurontin maximum dosage daily of RBP10 from an rRNA promoter. Testing the nonrandomness of breakage at a chromosome band is an essential step fo identifying a fragile site. A transpulmonary thermal-dye dilution (TDD) technique using cold indocyanine green dye was utilized to monitor cardiac index (CI) and preload in patients after heart transplantation. Targeting CK2 for glioblastoma treatment may benefit patients with glioblastoma. Caregiver burden was assessed using the Zarit Burden Interview (ZBI). In conclusion, late complications of the Takeuchi procedure are common, underscoring the importance of lifelong follow-up at a center with experience in treating coronary anomalies.

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To explain the pathogenesis of this abnormality, we evaluated selected parameters of primary hemostasis in patients with aortic valve stenosis before and after corrective surgery. While there is limited office-based anesthesia satisfaction data, limiting postoperative nausea and vomiting remains a major patient satisfier of which an occurrence rate of zero may be possible. Hemodynamic responses to sublingual nitroglycerin administration were evaluated before and after sustained therapy with transdermal nitroglycerin. Overall, athletes were relatively satisfied with their outcome, one year post hip arthroscopy, despite some having to adapt their sporting activities. To explore the adverse effects of primary closure compared with delayed closure for non bite traumatic wounds presenting within 24 hours post injury. The effects of equivalent doses of atropine and hyoscine following oral and i.m.

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