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Xenical is in a class of medications called lipase inhibitors. It works by preventing some of the fat in foods eaten from being absorbed in the intestines. This unabsorbed fat is then removed from the body in the stool.

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Also known as: Orlistat


Xenical (orlistat) blocks some of the fat that you eat, keeping it from being absorbed by your body.

Xenical is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet and is to used only by adults.

Xenical is the prescription-strength form of orlistat. The alli brand of orlistat is available without a prescription.


Xenical is taken orally 3 times a day during the main meal or up to 1 hour after the meal. The diet of the patient should include three main meals, containing the daily dose of fat, carbohydrate, and protein. The daily intake of fat should be no more than 30% of your total daily caloric intake (e.g., eating 1200 calories per day, no more than 360 of those calories should be in the form of fat). The dose of Xenical should be omitted if a meal is missed or does not contain fat. Treatment with Xenical should not continue for more than 6 months and should be stopped after 12 weeks if patient has been unable to lose at least 5 % of the body weight. If you lose enough weight for your BMI to fall below 28 kg/m², Xenical can no longer be supplied.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Xenical if you are allergic to its components. Do not take Xenical if you're pregnant, plan to have a baby or breastfeeding. Do not take Xenical usage in case of having anorexia or bulimia, diabetes, chronic malabsorption syndrome, gallbladder disease, kidney disease (kidney stones). Avoid taking medications for weight loss, anti-diabetes remedies; medications for lower cholesterol (pravastatin (Pravachol)), vitamins A, E, and K, cyclosporine (Sandimmune, Neoral), beta-carotene while taking Xenical. Avoid high-fat meals while taking Xenical. Xenical is approved to be taken along with nutritionally balanced, low-calorie diet and physical activity. Xenical is intended for use only in adults and can be dangerous for children. Do not stop taking Xenical suddenly. Xenical can be used by people with diabetes, high blood pressure, heart disease or high cholesterol.

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