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Zanaflex (Tizanidine)

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Zanaflex is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect muscles. It works by blocking chemical sensitive messengers in the brain.

Other names for this medication:

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Also known as: Tizanidine


Tizanidine is used to help relax certain muscles in your body. It relieves spasms, cramping, and tightness of the muscles caused by medical problems, such as multiple sclerosis or certain injuries to the spine. Tizanidine does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Tizanidine acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is available only with your doctor's prescription.


You should take it by mouth. It usually is taken two or three times a day. If you want to achieve most effective results do not stop taking Generic Zanaflex suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include weakness, drowsiness, confusion, slow heart rate, shallow breathing, feeling light-headed, or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Zanaflex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Zanaflex if you are allergic to tizanidine, or if:

you also take the antidepressant fluvoxamine (Luvox); or you also take the antibiotic ciprofloxacin (Cipro).

To make sure Zanaflex is safe for you, tell your doctor if you have ever had:

liver disease; kidney disease; or low blood pressure; or high blood pressure.

It is not known whether Zanaflex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It may not be safe to breastfeed while using tizanidine. Ask your doctor about any risk.

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